What is the NOAEL for Basic Blue 26?
Basic Blue 26 has 4 NOAEL studies in the database. The lowest reported value is Z1V8UTB56C UNII. Source: openFDA substances.
NOAEL Data
SVHC
REACH Registered
Cosmetic Ingredient
Basic Blue 26
Also known as: Methanaminium, N-[4-[[4-(dimethylamino)phenyl][4-(phenylamino)-1-naphthalenyl]methylene]-2,5-cyclohexadien-1-ylidene]-N-methyl-, chloride, Methanaminium, N-[4-[[4-(dimethylamino)phenyl][4-(phenylamino)-1-naphthalenyl]methylene]-2,5-cyclohexadien-1-ylidene]-N-methyl-, chloride (1:1), (4-((4-Anilino-1-naphthyl)(4-(dimethylamino)phenyl)methylene)cyclohexa-2,5-dien-1-ylidene)dimethylammonium chloride, N-(4-((4-(Dimethylamino)phenyl)(4-(phenylamino)-1-naphthalenyl)methylene)-2,5- cyclohexadien-1-ylidene)-N-methylmethanaminium, chloride, ADC Victoria Blue B (+15 more)
CAS 2580-56-5
Basic Blue 26 (CAS 2580-56-5) is a chemical substance; key hazard signal: Carcinogenic (Article 57a). Key regulatory status: SVHC Candidate List, REACH registered, 3 regulatory/inventory lists, cosmetic ingredient cross-reference; source data from EPA ToxValDB, EPA CPDat, AICIS, ECHA REACH, ECHA SVHC.
Cross-Vertical Regulatory Divergence
Basic Blue 26 is classified GHS Danger (H302, H317, H318, H319, H400, H410, H301, H351) in the chemicals database but is allowed in EU cosmetics.
SOURCE
Cross-vertical comparison
Cosmetics: ingredients.eu_status; Chemicals: ghs_classifications.signal_word/hazard_statement_code
SOURCE
noael studies public
NOAEL studies
4
SOURCE
chemical inventory jurisdictions
Regulatory lists
3
SOURCE
eu clp annex vi
GHS signal
Not classified
Chemical Identity
CAS, identifiers, formula, and alternate names for the matched substance record.
SOURCE
DSSTox identifiers
26 fields
Name
Basic Blue 26
CAS Number
2580-56-5
DTXSID
DTXSID0038889
Molecular Formula
C33H31N3.ClH
InChI Key
LLWJPGAKXJBKKA-UHFFFAOYSA-N
Monoisotopic Mass
505.228476
Synonyms
Methanaminium, N-[4-[[4-(dimethylamino)phenyl][4-(phenylamino)-1-naphthalenyl]methylene]-2,5-cyclohexadien-1-ylidene]-N-methyl-, chlorideMethanaminium, N-[4-[[4-(dimethylamino)phenyl][4-(phenylamino)-1-naphthalenyl]methylene]-2,5-cyclohexadien-1-ylidene]-N-methyl-, chloride (1:1)(4-((4-Anilino-1-naphthyl)(4-(dimethylamino)phenyl)methylene)cyclohexa-2,5-dien-1-ylidene)dimethylammonium chlorideN-(4-((4-(Dimethylamino)phenyl)(4-(phenylamino)-1-naphthalenyl)methylene)-2,5- cyclohexadien-1-ylidene)-N-methylmethanaminium, chlorideADC Victoria Blue BAizen Victoria Blue B BaseAizen Victoria Blue BHCalcozine Blue BEINECS 219-943-6Hecto Blue BHekto Blue BHidaco Victoria Blue B
Substance of Very High Concern (SVHC)
Candidate List status and reason under the ECHA REACH SVHC program.
SOURCE
ECHA (EU)
1 records
| Substance | Reason | Included |
|---|---|---|
| [4-[[4-anilino-1-naphthyl][4-(dimethylamino)phenyl]methylene]cyclohexa-2,5-dien-1-ylidene] dimethylammonium chloride (C.I. Basic Blue 26) | Carcinogenic (Article 57a) | 18-Jun-2012 |
Functional Uses
Industrial and product-use categories associated with this substance.
SOURCE
EPA CPDat
4 records
Dye
Regulatory Lists
Inventory, screening, and regulatory list matches from public chemical databases.
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EPA CPDat
3 records
| List | Keyword | Source |
|---|---|---|
| Europe; Personal care | European Commission | CosIng |
| banned; Europe; Personal care | European Commission | CosIng |
| Europe; Personal care; restricted | European Commission | CosIng |
NOAEL Studies
Toxicology endpoints rendered from public NOAEL study rows.
SOURCE
NOAEL studies
Showing 4 of 4 studies
| Value | Unit | Endpoint | Route | Species | Source |
|---|---|---|---|---|---|
| Z1V8UTB56C | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| Z1V8UTB56C | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| Z1V8UTB56C | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| Z1V8UTB56C | UNII | FDA UNII substance identifier | - | - | openFDA substances |
Showing 4 of 4 studies
REACH Registration
Registration status from the ECHA REACH registered substances database.
SOURCE
ECHA (EU)
1 records
| Status | Name | EC Number | Link |
|---|---|---|---|
| Registered | [4-[[4-anilino-1-naphthyl][4-(dimethylamino)phenyl]methylene]cyclohexa-2,5-dien-1-ylidene]dimethylammonium chloride | 219-943-6 | ECHA overview → |
Australian Status (AICIS)
Australian industrial chemicals inventory status and applicable conditions.
SOURCE
AICIS inventory
1 records
Inventory Status
listed
Cosmetic Safety Profile
Same-CAS cosmetic ingredient record for cross-vertical context.
SOURCE
CosIng / Ingredients DB
EU Status
permitted
Max
-
Category
Colorants
Frequently Asked Questions
What regulatory lists include Basic Blue 26?
Basic Blue 26 appears on 3 regulatory/inventory lists including Europe; Personal care, banned; Europe; Personal care, Europe; Personal care; restricted. Source: EPA CPDat.
Is Basic Blue 26 a Substance of Very High Concern (SVHC)?
Yes, Basic Blue 26 is listed on the ECHA REACH Candidate List as a Substance of Very High Concern. Reason: Carcinogenic (Article 57a). Source: ECHA SVHC Candidate List.
Is Basic Blue 26 used in cosmetics?
Yes, Basic Blue 26 is also indexed as a cosmetic ingredient under the name CI 44045. View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.
Where does the safety data for Basic Blue 26 come from?
Safety data is sourced from EPA ToxValDB, EPA CPDat, AICIS (Australian Industrial Chemicals Introduction Scheme), EPA DSSTox, ECHA REACH, ECHA SVHC Candidate List, CosIng / Ingredients DB. All data traces to primary regulatory sources and is updated from official government databases.
Does Basic Blue 26 have different safety status in cosmetics vs industrial chemicals?
Basic Blue 26 is classified GHS Danger (H302, H317, H318, H319, H400, H410, H301, H351) in the chemicals database but is allowed in EU cosmetics.
Is Basic Blue 26 used outside industrial chemicals?
Basic Blue 26 also appears in cosmetics databases.