What is the NOAEL for Sorbitan monohexadecanoate?
Sorbitan monohexadecanoate has 9 NOAEL studies in the database. The lowest reported value is 10 mg/kg bw/day in Consumers. Source: EFSA_OpenFoodTox_EFSA_ReferenceValues.xlsx.
NOAEL Data
REACH Registered
Cosmetic Ingredient
Sorbitan monohexadecanoate
Also known as: Sorbitan, monohexadecanoate, EINECS 247-568-8, Emsorb 2510, Liposorb P, Nikkol SP10 (+6 more)
CAS 26266-57-9
Sorbitan monohexadecanoate (CAS 26266-57-9) is a chemical substance. Key regulatory status: REACH registered, 7 regulatory/inventory lists, cosmetic ingredient cross-reference; source data from EPA ToxValDB, EPA CPDat, AICIS, ECHA REACH.
SOURCE
noael studies public
NOAEL studies
9
SOURCE
chemical inventory jurisdictions
Regulatory lists
7
SOURCE
eu clp annex vi
GHS signal
Not classified
Chemical Identity
CAS, identifiers, formula, and alternate names for the matched substance record.
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DSSTox identifiers
14 fields
Name
Sorbitan monohexadecanoate
CAS Number
26266-57-9
DTXSID
DTXSID6029335
Synonyms
Sorbitan, monohexadecanoateEINECS 247-568-8Emsorb 2510Liposorb PNikkol SP10Nissan nonion PP40Nonion PP40Protachem SMPSorbitan palmitasSorbitani palmitasUNII-77K6Z421KU
Functional Uses
Industrial and product-use categories associated with this substance.
SOURCE
EPA CPDat
16 records
EmulsifierSurfactant (surface active agent)Dispersing agentWetting agent (non-aqueous)
Regulatory Lists
Inventory, screening, and regulatory list matches from public chemical databases.
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EPA CPDat
7 records
| List | Keyword | Source |
|---|---|---|
| inert_ingredient; non_food_use; Pesticides | EPA | CPCat |
| inert_ingredient; Pesticides | EPA | CPCat |
| drinking_water; Europe; manufacturing; plastic_additive | Belgaqua | CPCat |
| Indirect additives food contact (10/2018) | FDA | United States Food and Drug Administration (FDA) |
| SCIL (9/2019) | USEPA | Safer Chemical Ingredients List |
| pharmaceutical | US International Trade Commission | CPCat |
| Europe; plastic_additive | European Chemicals Agency | European Chemicals Agency (ECHA) |
NOAEL Studies
Toxicology endpoints rendered from public NOAEL study rows.
SOURCE
NOAEL studies
Showing 9 of 9 studies
| Value | Unit | Endpoint | Route | Species | Source |
|---|---|---|---|---|---|
| =10 | mg/kg bw/day | ADI (group) | - | Consumers | EFSA_OpenFoodTox_EFSA_ReferenceValues.xlsx |
| =10 | mg/kg bw/day | ADI (group) | - | Consumers | EFSA_OpenFoodTox_EFSA_ReferenceValues.xlsx |
| 77K6Z421KU | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 77K6Z421KU | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 77K6Z421KU | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 77K6Z421KU | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| >15900 | mg/kg bw | LD50 | oral | Rat | NTP_ICE_acute_oral |
| =2600 | mg/kg bw/day | NOAEL | oral | Mouse | ToxValDB_EFSA |
| =2600 | mg/kg bw/day | NOAEL | oral: feed | Mouse | EFSA_OpenFoodTox_EFSA_ReferencePoints.xlsx |
Showing 9 of 9 studies
REACH Registration
Registration status from the ECHA REACH registered substances database.
SOURCE
ECHA (EU)
1 records
| Status | Name | EC Number | Link |
|---|---|---|---|
| Registered | Sorbitan palmitate | 247-568-8 | ECHA overview → |
Australian Status (AICIS)
Australian industrial chemicals inventory status and applicable conditions.
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AICIS inventory
1 records
Inventory Status
listed
Cosmetic Safety Profile
Same-CAS cosmetic ingredient record for cross-vertical context.
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CosIng / Ingredients DB
EU Status
permitted
Max
-
Category
Surfactant
Pharmaceutical Data
Same-CAS pharmaceutical records from drug and bioactivity sources.
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EMBL-EBI ChEMBL
SORBITAN MONOPALMITATE
ChEMBL Phase
2
Adverse Events
0
Bioactivity
0
Food Safety Data
Same-CAS food additive, ADI, and GRAS records where available.
SOURCE
EFSA / FDA GRAS
1 records
E495 — ADI: 25 mg/kg bw
View full food safety profile →Cannabis Data
Same-CAS cannabis compliance and lab records where available.
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Cannabis regulatory / lab data
efsa substances
1 cannabis record found in efsa substances.
View full cannabis profile →Frequently Asked Questions
What regulatory lists include Sorbitan monohexadecanoate?
Sorbitan monohexadecanoate appears on 7 regulatory/inventory lists including inert_ingredient; non_food_use; Pesticides, inert_ingredient; Pesticides, drinking_water; Europe; manufacturing; plastic_additive, and 4 more. Source: EPA CPDat.
Is Sorbitan monohexadecanoate used in cosmetics?
Yes, Sorbitan monohexadecanoate is also indexed as a cosmetic ingredient under the name SORBITAN PALMITATE. View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.
Where does the safety data for Sorbitan monohexadecanoate come from?
Safety data is sourced from EPA ToxValDB, EPA CPDat, AICIS (Australian Industrial Chemicals Introduction Scheme), EPA DSSTox, ECHA REACH, CosIng / Ingredients DB, ChEMBL / DailyMed, EFSA / FDA GRAS, cannabis regulatory/lab databases. All data traces to primary regulatory sources and is updated from official government databases.
Is Sorbitan monohexadecanoate used outside industrial chemicals?
Sorbitan monohexadecanoate also appears in cosmetics, pharmaceutical, food safety, cannabis databases.