What is the NOAEL for 2-Ethyl-3,(5 or 6)-dimethylpyrazine?
2-Ethyl-3,(5 or 6)-dimethylpyrazine has 1 NOAEL study in the database. The lowest reported value is 15 mg/kg bw/day via oral in rat. Source: COSMOS_DB.
NOAEL Data
Cosmetic Ingredient
2-Ethyl-3,(5 or 6)-dimethylpyrazine
Also known as: Pyrazine, 2-ethyl-3,?-dimethyl-, Pyrazine, 2-ethyl-3,(5 or 6)-dimethyl-, 2-Ethyl-3,5(6)-dimethylpyrazine, 2-Ethyl-3,?-dimethylpyrazine, EC No.: 248-182-2
CAS 27043-05-6
2-Ethyl-3,(5 or 6)-dimethylpyrazine (CAS 27043-05-6) is a chemical substance. Key regulatory status: 4 regulatory/inventory lists, cosmetic ingredient cross-reference; source data from EPA ToxValDB, EPA CPDat, AICIS.
View cosmetic safety profile for 2-Ethyl-3,(5 Or 6)-Dimethylpyrazine →
SOURCE
noael studies public
NOAEL studies
1
SOURCE
chemical inventory jurisdictions
Regulatory lists
4
SOURCE
eu clp annex vi
GHS signal
Not classified
Chemical Identity
CAS, identifiers, formula, and alternate names for the matched substance record.
SOURCE
DSSTox identifiers
8 fields
Name
2-Ethyl-3,(5 or 6)-dimethylpyrazine
CAS Number
27043-05-6
DTXSID
DTXSID301010976
Synonyms
Pyrazine, 2-ethyl-3,?-dimethyl-Pyrazine, 2-ethyl-3,(5 or 6)-dimethyl-2-Ethyl-3,5(6)-dimethylpyrazine2-Ethyl-3,?-dimethylpyrazineEC No.: 248-182-2
Functional Uses
Industrial and product-use categories associated with this substance.
SOURCE
EPA CPDat
5 records
FragranceFlavouring and nutrient
Regulatory Lists
Inventory, screening, and regulatory list matches from public chemical databases.
SOURCE
EPA CPDat
4 records
| List | Keyword | Source |
|---|---|---|
| Europe | European Commission | Fl@vis |
| food_additive; Substances Added to Food (formerly EAFUS) (2/2019) | FDA | United States Food and Drug Administration (FDA) |
| IFRA Transparency | IFRA | IFRA |
| Europe | European Commission | Fl@vis |
NOAEL Studies
Toxicology endpoints rendered from public NOAEL study rows.
SOURCE
NOAEL studies
Showing 1 of 1 studies
| Value | Unit | Endpoint | Route | Species | Source |
|---|---|---|---|---|---|
| 15 | mg/kg bw/day | NOAEL | oral | rat | COSMOS_DB |
Showing 1 of 1 studies
Australian Status (AICIS)
Australian industrial chemicals inventory status and applicable conditions.
SOURCE
AICIS inventory
1 records
Inventory Status
listed
Cosmetic Safety Profile
Same-CAS cosmetic ingredient record for cross-vertical context.
SOURCE
CosIng / Ingredients DB
EU Status
permitted
Max
-
Category
Fragrance
Frequently Asked Questions
What regulatory lists include 2-Ethyl-3,(5 or 6)-dimethylpyrazine?
2-Ethyl-3,(5 or 6)-dimethylpyrazine appears on 3 regulatory/inventory lists including Europe, food_additive; Substances Added to Food (formerly EAFUS) (2/2019), IFRA Transparency. Source: EPA CPDat.
Is 2-Ethyl-3,(5 or 6)-dimethylpyrazine used in cosmetics?
Yes, 2-Ethyl-3,(5 or 6)-dimethylpyrazine is also indexed as a cosmetic ingredient under the name 2-Ethyl-3,(5 Or 6)-Dimethylpyrazine. View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.
Where does the safety data for 2-Ethyl-3,(5 or 6)-dimethylpyrazine come from?
Safety data is sourced from EPA ToxValDB, EPA CPDat, AICIS (Australian Industrial Chemicals Introduction Scheme), EPA DSSTox, CosIng / Ingredients DB. All data traces to primary regulatory sources and is updated from official government databases.
Is 2-Ethyl-3,(5 or 6)-dimethylpyrazine used outside industrial chemicals?
2-Ethyl-3,(5 or 6)-dimethylpyrazine also appears in cosmetics databases.