NOAEL Data REACH Registered Cosmetic Ingredient

Hexanoic acid, 2-ethyl-, ethyl ester

CAS 2983-37-1

Hexanoic acid, 2-ethyl-, ethyl ester (CAS 2983-37-1) is a chemical substance. Key regulatory status: REACH registered, 3 regulatory/inventory lists, cosmetic ingredient cross-reference; source data from EPA ToxValDB, EPA CPDat, AICIS, ECHA REACH.

View cosmetic safety profile for Ethyl Ethylhexanoate →

SOURCE noael studies public
NOAEL studies
7
SOURCE chemical inventory jurisdictions
Regulatory lists
3
SOURCE eu clp annex vi
GHS signal
Not classified

Chemical Identity

CAS, identifiers, formula, and alternate names for the matched substance record.

SOURCE DSSTox identifiers 6 fields
Name
Hexanoic acid, 2-ethyl-, ethyl ester
CAS Number
2983-37-1
DTXSID
DTXSID40863070
Molecular Formula
C10H20O2
InChI Key
YXAGIRHBJJLWHW-UHFFFAOYSA-N
Monoisotopic Mass
172.14633

Functional Uses

Industrial and product-use categories associated with this substance.

SOURCE EPA CPDat 5 records
FragranceFlavouring and nutrient

Regulatory Lists

Inventory, screening, and regulatory list matches from public chemical databases.

SOURCE EPA CPDat 3 records
ListKeywordSource
IFRA TransparencyIFRAIFRA
food_additive; Substances Added to Food (formerly EAFUS) (2/2019)FDAUnited States Food and Drug Administration (FDA)
consumer_productP&GProctor & Gamble

NOAEL Studies

Toxicology endpoints rendered from public NOAEL study rows.

SOURCE NOAEL studies Showing 7 of 7 studies
ValueUnitEndpointRouteSpeciesSource
G42R59N31IUNIIFDA UNII substance identifier--openFDA substances
G42R59N31IUNIIFDA UNII substance identifier--openFDA substances
G42R59N31IUNIIFDA UNII substance identifier--openFDA substances
G42R59N31IUNIIFDA UNII substance identifier--openFDA substances
-%Incidence of positive responsesDermalHumanNTP_ICE_skin_sensitization
8100ug/cm2Induction dose per skin areaDermalHumanNTP_ICE_skin_sensitization
3unitlessRelative reliability scoreDermalHumanNTP_ICE_skin_sensitization

Showing 7 of 7 studies

REACH Registration

Registration status from the ECHA REACH registered substances database.

SOURCE ECHA (EU) 1 records
StatusNameEC NumberLink
RegisteredEthyl 2-ethylhexanoate221-043-3ECHA overview →

Australian Status (AICIS)

Australian industrial chemicals inventory status and applicable conditions.

SOURCE AICIS inventory 1 records
Inventory Status
listed

Cosmetic Safety Profile

Same-CAS cosmetic ingredient record for cross-vertical context.

SOURCE CosIng / Ingredients DB
EU Status
permitted
Max
-
Category
Emollient
View full cosmetic safety profile →

Food Safety Data

Same-CAS food additive, ADI, and GRAS records where available.

SOURCE EFSA / FDA GRAS 1 records

ADI: No safety concern at current levels of intake when used as a flavouring agentt mg/kg bw

View full food safety profile →

Frequently Asked Questions

What is the NOAEL for Hexanoic acid, 2-ethyl-, ethyl ester?

Hexanoic acid, 2-ethyl-, ethyl ester has 7 NOAEL studies in the database. The lowest reported value is G42R59N31I UNII. Source: openFDA substances.

What regulatory lists include Hexanoic acid, 2-ethyl-, ethyl ester?

Hexanoic acid, 2-ethyl-, ethyl ester appears on 3 regulatory/inventory lists including IFRA Transparency, food_additive; Substances Added to Food (formerly EAFUS) (2/2019), consumer_product. Source: EPA CPDat.

Is Hexanoic acid, 2-ethyl-, ethyl ester used in cosmetics?

Yes, Hexanoic acid, 2-ethyl-, ethyl ester is also indexed as a cosmetic ingredient under the name Ethyl Ethylhexanoate. View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.

Where does the safety data for Hexanoic acid, 2-ethyl-, ethyl ester come from?

Safety data is sourced from EPA ToxValDB, EPA CPDat, AICIS (Australian Industrial Chemicals Introduction Scheme), EPA DSSTox, ECHA REACH, CosIng / Ingredients DB, EFSA / FDA GRAS. All data traces to primary regulatory sources and is updated from official government databases.

Is Hexanoic acid, 2-ethyl-, ethyl ester used outside industrial chemicals?

Hexanoic acid, 2-ethyl-, ethyl ester also appears in cosmetics, food safety databases.