What is the NOAEL for Potassium D-gluconate?
Potassium D-gluconate has 6 NOAEL studies in the database. The lowest reported value is 59 mg/m3 via inhalation in Human. Source: ToxValDB_GESTIS_DNEL.
NOAEL Data
REACH Registered
Cosmetic Ingredient
Potassium D-gluconate
Also known as: Gluconic acid, monopotassium salt, D-, D-Gluconic acid, potassium salt (1:1), EINECS 206-074-2, Gluconic acid, monopotassium salt, Gluconic acid potassium salt (+10 more)
CAS 299-27-4
Potassium D-gluconate (CAS 299-27-4) is a chemical substance. Key regulatory status: REACH registered, 6 regulatory/inventory lists, cosmetic ingredient cross-reference; source data from EPA ToxValDB, EPA CPDat, AICIS, ECHA REACH.
SOURCE
noael studies public
NOAEL studies
6
SOURCE
chemical inventory jurisdictions
Regulatory lists
6
SOURCE
eu clp annex vi
GHS signal
Not classified
Chemical Identity
CAS, identifiers, formula, and alternate names for the matched substance record.
SOURCE
DSSTox identifiers
21 fields
Name
Potassium D-gluconate
CAS Number
299-27-4
DTXSID
DTXSID7029617
Molecular Formula
C6H12O7.K
InChI Key
HLCFGWHYROZGBI-JJKGCWMISA-M
Monoisotopic Mass
235.022009
Synonyms
Gluconic acid, monopotassium salt, D-D-Gluconic acid, potassium salt (1:1)EINECS 206-074-2Gluconic acid, monopotassium saltGluconic acid potassium saltGluconsan KKalium-betaKalium GluconateKaon elixirKatorinPotaliumPotasoral
Functional Uses
Industrial and product-use categories associated with this substance.
SOURCE
EPA CPDat
9 records
HumectantChelating agentSoftener and conditionerFlavouring and nutrient
Regulatory Lists
Inventory, screening, and regulatory list matches from public chemical databases.
SOURCE
EPA CPDat
6 records
| List | Keyword | Source |
|---|---|---|
| inert_ingredient; non_food_use; Pesticides | EPA | CPCat |
| Europe; supplements | EU | CPCat |
| Europe; food_additive; supplements | EU | CPCat |
| food_additive; Substances Added to Food (formerly EAFUS) (2/2019) | FDA | United States Food and Drug Administration (FDA) |
| SCIL (9/2019) | USEPA | Safer Chemical Ingredients List |
| Canada; pharmaceutical | DrugBank | DrugBank |
NOAEL Studies
Toxicology endpoints rendered from public NOAEL study rows.
SOURCE
NOAEL studies
Showing 6 of 6 studies
| Value | Unit | Endpoint | Route | Species | Source |
|---|---|---|---|---|---|
| =59 | mg/m3 | DNEL systemic | inhalation | Human | ToxValDB_GESTIS_DNEL |
| 12H3K5QKN9 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 12H3K5QKN9 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 12H3K5QKN9 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 12H3K5QKN9 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| =10380 | mg/kg bw | LD50 | oral | Rat | NTP_ICE_acute_oral |
Showing 6 of 6 studies
REACH Registration
Registration status from the ECHA REACH registered substances database.
SOURCE
ECHA (EU)
1 records
| Status | Name | EC Number | Link |
|---|---|---|---|
| Registered | Potassium gluconate | 206-074-2 | ECHA overview → |
Australian Status (AICIS)
Australian industrial chemicals inventory status and applicable conditions.
SOURCE
AICIS inventory
1 records
Inventory Status
listed
Cosmetic Safety Profile
Same-CAS cosmetic ingredient record for cross-vertical context.
SOURCE
CosIng / Ingredients DB
EU Status
permitted
Max
-
Category
Cosmetic Ingredient
Pharmaceutical Data
Same-CAS pharmaceutical records from drug and bioactivity sources.
SOURCE
EMBL-EBI ChEMBL
POTASSIUM GLUCONATE
ChEMBL Phase
1
Adverse Events
301
Bioactivity
0
Food Safety Data
Same-CAS food additive, ADI, and GRAS records where available.
SOURCE
EFSA / FDA GRAS
1 records
E577 — ADI: NOT SPECIFIED mg/kg bw
View full food safety profile →Frequently Asked Questions
What regulatory lists include Potassium D-gluconate?
Potassium D-gluconate appears on 6 regulatory/inventory lists including inert_ingredient; non_food_use; Pesticides, Europe; supplements, Europe; food_additive; supplements, and 3 more. Source: EPA CPDat.
Is Potassium D-gluconate used in cosmetics?
Yes, Potassium D-gluconate is also indexed as a cosmetic ingredient under the name Potassium Gluconate. View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.
Where does the safety data for Potassium D-gluconate come from?
Safety data is sourced from EPA ToxValDB, EPA CPDat, AICIS (Australian Industrial Chemicals Introduction Scheme), EPA DSSTox, ECHA REACH, CosIng / Ingredients DB, ChEMBL / DailyMed, EFSA / FDA GRAS. All data traces to primary regulatory sources and is updated from official government databases.
Is Potassium D-gluconate used outside industrial chemicals?
Potassium D-gluconate also appears in cosmetics, pharmaceutical, food safety databases.