NOAEL Data REACH Registered Cosmetic Ingredient

2-Aminoethanesulfinic acid

Also known as: Hypotaurine, Ethanesulfinic acid, 2-amino-, UNII-5L08GE4332, 2-ammonioethanesulfinate, 2-azaniumylethane-1-sulfinate (+2 more)

CAS 300-84-5

2-Aminoethanesulfinic acid (CAS 300-84-5) is a chemical substance. Key regulatory status: REACH registered, cosmetic ingredient cross-reference; source data from EPA ToxValDB, EPA CPDat, ECHA REACH.

View cosmetic safety profile for Aminoethanesulfinic Acid (Hypotaurine) →

SOURCE noael studies public
NOAEL studies
4
SOURCE chemical inventory jurisdictions
Regulatory lists
0
SOURCE eu clp annex vi
GHS signal
Not classified

Chemical Identity

CAS, identifiers, formula, and alternate names for the matched substance record.

SOURCE DSSTox identifiers 13 fields
Name
2-Aminoethanesulfinic acid
CAS Number
300-84-5
DTXSID
DTXSID8075380
Molecular Formula
C2H7NO2S
InChI Key
VVIUBCNYACGLLV-UHFFFAOYSA-N
Monoisotopic Mass
109.01975
Synonyms
HypotaurineEthanesulfinic acid, 2-amino-UNII-5L08GE43322-ammonioethanesulfinate2-azaniumylethane-1-sulfinate2-mmonioethane-1-sulfinatehypotaurine zwitterion

Functional Uses

Industrial and product-use categories associated with this substance.

SOURCE EPA CPDat 2 records
AntioxidantReducing agent

NOAEL Studies

Toxicology endpoints rendered from public NOAEL study rows.

SOURCE NOAEL studies Showing 4 of 4 studies
ValueUnitEndpointRouteSpeciesSource
5L08GE4332UNIIFDA UNII substance identifier--openFDA substances
5L08GE4332UNIIFDA UNII substance identifier--openFDA substances
5L08GE4332UNIIFDA UNII substance identifier--openFDA substances
5L08GE4332UNIIFDA UNII substance identifier--openFDA substances

Showing 4 of 4 studies

REACH Registration

Registration status from the ECHA REACH registered substances database.

SOURCE ECHA (EU) 1 records
StatusNameEC NumberLink
Registered2-aminoethanesulfinic acid428-720-4ECHA overview →

Cosmetic Safety Profile

Same-CAS cosmetic ingredient record for cross-vertical context.

SOURCE CosIng / Ingredients DB
EU Status
permitted
Max
-
Category
Antioxidant
View full cosmetic safety profile →

Pharmaceutical Data

Same-CAS pharmaceutical records from drug and bioactivity sources.

SOURCE EMBL-EBI ChEMBL HYPOTAURINE
ChEMBL Phase
Not listed
Adverse Events
0
Bioactivity
1
View full pharmaceutical profile →

Frequently Asked Questions

What is the NOAEL for 2-Aminoethanesulfinic acid?

2-Aminoethanesulfinic acid has 4 NOAEL studies in the database. The lowest reported value is 5L08GE4332 UNII. Source: openFDA substances.

Is 2-Aminoethanesulfinic acid used in cosmetics?

Yes, 2-Aminoethanesulfinic acid is also indexed as a cosmetic ingredient under the name Aminoethanesulfinic Acid (Hypotaurine). View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.

Where does the safety data for 2-Aminoethanesulfinic acid come from?

Safety data is sourced from EPA ToxValDB, EPA CPDat, EPA DSSTox, ECHA REACH, CosIng / Ingredients DB, ChEMBL / DailyMed. All data traces to primary regulatory sources and is updated from official government databases.

Is 2-Aminoethanesulfinic acid used outside industrial chemicals?

2-Aminoethanesulfinic acid also appears in cosmetics, pharmaceutical databases.