What is the NOAEL for 2-Isocyanatoethyl methacrylate?
2-Isocyanatoethyl methacrylate has 10 NOAEL studies in the database. The lowest reported value is 828DBI7X91 UNII. Source: openFDA substances.
NOAEL Data
REACH Registered
Cosmetic Ingredient
2-Isocyanatoethyl methacrylate
Also known as: BRN 1768533, EINECS 250-284-7, beta-Isocyanatoethyl methacrylate, Isocyanoethyl methacrylate, Metharcyclic acid, 2-isocyanatoethyl ester (+1 more)
CAS 30674-80-7
2-Isocyanatoethyl methacrylate (CAS 30674-80-7) is a chemical substance. Key regulatory status: REACH registered, cosmetic ingredient cross-reference; source data from EPA ToxValDB, EPA CPDat, AICIS, ECHA REACH.
View cosmetic safety profile for Methacryloyloxyethyl Isocyanate →
Cross-Vertical Regulatory Divergence
2-Isocyanatoethyl methacrylate is prohibited in EU cosmetics but has active industrial GHS classifications (H302, H315, H317, H318, H319, H330, H334, H335).
SOURCE
Cross-vertical comparison
Cosmetics: ingredients.eu_status; Chemicals: ghs_classifications.signal_word/hazard_statement_code
SOURCE
noael studies public
NOAEL studies
10
SOURCE
chemical inventory jurisdictions
Regulatory lists
0
SOURCE
eu clp annex vi
GHS signal
Not classified
Chemical Identity
CAS, identifiers, formula, and alternate names for the matched substance record.
SOURCE
DSSTox identifiers
12 fields
Name
2-Isocyanatoethyl methacrylate
CAS Number
30674-80-7
DTXSID
DTXSID6051986
Molecular Formula
C7H9NO3
InChI Key
RBQRWNWVPQDTJJ-UHFFFAOYSA-N
Monoisotopic Mass
155.058243
Synonyms
BRN 1768533EINECS 250-284-7beta-Isocyanatoethyl methacrylateIsocyanoethyl methacrylateMetharcyclic acid, 2-isocyanatoethyl esterUNII-828DBI7X91
Functional Uses
Industrial and product-use categories associated with this substance.
SOURCE
EPA CPDat
2 records
Chemical reaction regulatorNo specific technical function
NOAEL Studies
Toxicology endpoints rendered from public NOAEL study rows.
SOURCE
NOAEL studies
Showing 10 of 10 studies
| Value | Unit | Endpoint | Route | Species | Source |
|---|---|---|---|---|---|
| 828DBI7X91 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 828DBI7X91 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 828DBI7X91 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 828DBI7X91 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 0.0254 | mg/L | LC50 | Inhalation | - | NTP_ICE_acute_inhalation |
| =670 | mg/kg bw | LD50 | oral | Rat | NTP_ICE_acute_oral |
| =1257 | mg/kg bw | LD50 | oral | Rat | NTP_ICE_acute_oral |
| =1541 | mg/kg bw | LD50 | oral | Rat | NTP_ICE_acute_oral |
| =1814 | mg/kg bw | LD50 | oral | Rat | NTP_ICE_acute_oral |
| >=110 | mg/kg bw/day | NOAEL | oral | Rat | ToxValDB_ECHA_IUCLID |
Showing 10 of 10 studies
REACH Registration
Registration status from the ECHA REACH registered substances database.
SOURCE
ECHA (EU)
1 records
| Status | Name | EC Number | Link |
|---|---|---|---|
| Registered | 2-isocyanatoethyl methacrylate | 250-284-7 | ECHA overview → |
Australian Status (AICIS)
Australian industrial chemicals inventory status and applicable conditions.
SOURCE
AICIS inventory
1 records
Inventory Status
listed
Cosmetic Safety Profile
Same-CAS cosmetic ingredient record for cross-vertical context.
SOURCE
CosIng / Ingredients DB
EU Status
prohibited
Max
-
Category
Cosmetic Ingredient
Frequently Asked Questions
Is 2-Isocyanatoethyl methacrylate used in cosmetics?
Yes, 2-Isocyanatoethyl methacrylate is also indexed as a cosmetic ingredient under the name Methacryloyloxyethyl Isocyanate. View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.
Where does the safety data for 2-Isocyanatoethyl methacrylate come from?
Safety data is sourced from EPA ToxValDB, EPA CPDat, AICIS (Australian Industrial Chemicals Introduction Scheme), EPA DSSTox, ECHA REACH, CosIng / Ingredients DB. All data traces to primary regulatory sources and is updated from official government databases.
Does 2-Isocyanatoethyl methacrylate have different safety status in cosmetics vs industrial chemicals?
2-Isocyanatoethyl methacrylate is prohibited in EU cosmetics but has active industrial GHS classifications (H302, H315, H317, H318, H319, H330, H334, H335).
Is 2-Isocyanatoethyl methacrylate used outside industrial chemicals?
2-Isocyanatoethyl methacrylate also appears in cosmetics databases.