NOAEL Data REACH Registered Cosmetic Ingredient

L-Ornithine monohydrochloride

Also known as: L-Ornithine hydrochloride (1:1), 2,5-Diaminopentanoic acid hydrochloride, EINECS 221-678-6, NSC 118360, Ornithine L monochlorohydrate (+5 more)

CAS 3184-13-2

L-Ornithine monohydrochloride (CAS 3184-13-2) is a chemical substance. Key regulatory status: REACH registered, 1 regulatory/inventory list, cosmetic ingredient cross-reference; source data from EPA ToxValDB, EPA CPDat, AICIS, ECHA REACH.

View cosmetic safety profile for ORNITHINE HCL →

SOURCE noael studies public
NOAEL studies
5
SOURCE chemical inventory jurisdictions
Regulatory lists
1
SOURCE eu clp annex vi
GHS signal
Not classified

Chemical Identity

CAS, identifiers, formula, and alternate names for the matched substance record.

SOURCE DSSTox identifiers 16 fields
Name
L-Ornithine monohydrochloride
CAS Number
3184-13-2
DTXSID
DTXSID50858851
Molecular Formula
C5H12N2O2.ClH
InChI Key
GGTYBZJRPHEQDG-WCCKRBBISA-N
Monoisotopic Mass
168.066555
Synonyms
L-Ornithine hydrochloride (1:1)2,5-Diaminopentanoic acid hydrochlorideEINECS 221-678-6NSC 118360Ornithine L monochlorohydrateL-Ornithine hydrochlorideOrnithine hydrochlorideOrnithine monohydrochlorideOrnithine L- HClUNII-HBK84K66XH

Functional Uses

Industrial and product-use categories associated with this substance.

SOURCE EPA CPDat 5 records
Softener and conditionerFlavouring and nutrient

Regulatory Lists

Inventory, screening, and regulatory list matches from public chemical databases.

SOURCE EPA CPDat 1 records
ListKeywordSource
food_additive; Substances Added to Food (formerly EAFUS) (2/2019)FDAUnited States Food and Drug Administration (FDA)

NOAEL Studies

Toxicology endpoints rendered from public NOAEL study rows.

SOURCE NOAEL studies Showing 5 of 5 studies
ValueUnitEndpointRouteSpeciesSource
HBK84K66XHUNIIFDA UNII substance identifier--openFDA substances
HBK84K66XHUNIIFDA UNII substance identifier--openFDA substances
HBK84K66XHUNIIFDA UNII substance identifier--openFDA substances
HBK84K66XHUNIIFDA UNII substance identifier--openFDA substances
=10000mg/kg bwLD50oralRatNTP_ICE_acute_oral

Showing 5 of 5 studies

REACH Registration

Registration status from the ECHA REACH registered substances database.

SOURCE ECHA (EU) 1 records
StatusNameEC NumberLink
RegisteredL-(+)-2,5-diaminopentanoic acid221-678-6ECHA overview →

Australian Status (AICIS)

Australian industrial chemicals inventory status and applicable conditions.

SOURCE AICIS inventory 1 records
Inventory Status
listed

Cosmetic Safety Profile

Same-CAS cosmetic ingredient record for cross-vertical context.

SOURCE CosIng / Ingredients DB
EU Status
permitted
Max
-
Category
Skin Conditioning
View full cosmetic safety profile →

Pharmaceutical Data

Same-CAS pharmaceutical records from drug and bioactivity sources.

SOURCE EMBL-EBI ChEMBL CHEMBL3184113
ChEMBL Phase
Not listed
Adverse Events
0
Bioactivity
0
View full pharmaceutical profile →

Food Safety Data

Same-CAS food additive, ADI, and GRAS records where available.

SOURCE EFSA / FDA GRAS 1 records

1 food-safety record found.

View full food safety profile →

Frequently Asked Questions

What is the NOAEL for L-Ornithine monohydrochloride?

L-Ornithine monohydrochloride has 5 NOAEL studies in the database. The lowest reported value is HBK84K66XH UNII. Source: openFDA substances.

What regulatory lists include L-Ornithine monohydrochloride?

L-Ornithine monohydrochloride appears on 1 regulatory/inventory list including food_additive; Substances Added to Food (formerly EAFUS) (2/2019). Source: EPA CPDat.

Is L-Ornithine monohydrochloride used in cosmetics?

Yes, L-Ornithine monohydrochloride is also indexed as a cosmetic ingredient under the name ORNITHINE HCL. View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.

Where does the safety data for L-Ornithine monohydrochloride come from?

Safety data is sourced from EPA ToxValDB, EPA CPDat, AICIS (Australian Industrial Chemicals Introduction Scheme), EPA DSSTox, ECHA REACH, CosIng / Ingredients DB, ChEMBL / DailyMed, EFSA / FDA GRAS. All data traces to primary regulatory sources and is updated from official government databases.

Is L-Ornithine monohydrochloride used outside industrial chemicals?

L-Ornithine monohydrochloride also appears in cosmetics, pharmaceutical, food safety databases.