NOAEL Data Prop 65 REACH Registered Cosmetic Ingredient

C.I. Pigment Orange 5

Also known as: 2-Naphthalenol, 1-[(2,4-dinitrophenyl)azo]-, D&C Orange No. 17, 2-Naphthalenol, 1-[2-(2,4-dinitrophenyl)diazenyl]-, D & C Orange No. 17, D and C Orange No. 17 (+15 more)

CAS 3468-63-1

C.I. Pigment Orange 5 (CAS 3468-63-1) is a chemical substance; key hazard signal: cancer. Key regulatory status: California Proposition 65, REACH registered, 9 regulatory/inventory lists, cosmetic ingredient cross-reference; source data from EPA ToxValDB, EPA CPDat, AICIS, ECHA REACH, CA Prop 65.

View cosmetic safety profile for CI 12480 →

SOURCE noael studies public
NOAEL studies
7
SOURCE chemical inventory jurisdictions
Regulatory lists
9
SOURCE eu clp annex vi
GHS signal
Not classified

Chemical Identity

CAS, identifiers, formula, and alternate names for the matched substance record.

SOURCE DSSTox identifiers 26 fields
Name
C.I. Pigment Orange 5
CAS Number
3468-63-1
DTXSID
DTXSID6029258
Molecular Formula
C16H10N4O5
InChI Key
HBHZKFOUIUMKHV-UHFFFAOYSA-N
Monoisotopic Mass
338.065119
Synonyms
2-Naphthalenol, 1-[(2,4-dinitrophenyl)azo]-D&C Orange No. 172-Naphthalenol, 1-[2-(2,4-dinitrophenyl)diazenyl]-D & C Orange No. 17D and C Orange No. 17D&C Orange 1711048 OrangeBrilliant tangerine 13030BRN 0964718Calcotone Orange 2RCarnelio Red 2GChromatex Orange R

California Proposition 65

California OEHHA listing status and toxicity category.

SOURCE California OEHHA Proposition 65 List 1 records
ChemicalToxicity TypeCancerDevelopmentalListed
-cancerYesNo-

Functional Uses

Industrial and product-use categories associated with this substance.

SOURCE EPA CPDat 5 records
DyePigment

Regulatory Lists

Inventory, screening, and regulatory list matches from public chemical databases.

SOURCE EPA CPDat 9 records
ListKeywordSource
Arts and crafts/Office supplies - body paint - tattoo ink; EuropeDanish Environmental Protection AgencyDanish EPA
Arts and crafts/Office supplies - body paint - tattoo ink; EuropeDanish Environmental Protection AgencyDanish EPA
Arts and crafts/Office supplies - body paint - tattoo ink; EuropeDanish Environmental Protection AgencyDanish EPA
inert_ingredient; non_food_use; PesticidesEPACPCat
banned; Europe; Personal careEuropean CommissionCosIng
OEHHA Proposition 65 (3/2019)STATE OF CALIFORNIA ENVIRONMENTAL PROTECTION AGENCYOEHHA Proposition 65 List
OEHHA Proposition 65 (1/2023)California Office of Environmental Health Hazard AssessmentOEHHA Proposition 65 List
Arts and crafts/Office supplies - body paint - tattoo ink; EuropeDanish Environmental Protection AgencyDanish EPA
Personal care; prohibited; Southeast AsiaAseanASEAN Cosmetics

NOAEL Studies

Toxicology endpoints rendered from public NOAEL study rows.

SOURCE NOAEL studies Showing 7 of 7 studies
ValueUnitEndpointRouteSpeciesSource
ABcancerlisting typeCalifornia Proposition 65 listing--California Proposition 65
ABcancerlisting typeCalifornia Proposition 65 listing--California Proposition 65
ABcancerlisting typeCalifornia Proposition 65 listing--California Proposition 65
E27LT0986OUNIIFDA UNII substance identifier--openFDA substances
E27LT0986OUNIIFDA UNII substance identifier--openFDA substances
E27LT0986OUNIIFDA UNII substance identifier--openFDA substances
E27LT0986OUNIIFDA UNII substance identifier--openFDA substances

Showing 7 of 7 studies

REACH Registration

Registration status from the ECHA REACH registered substances database.

SOURCE ECHA (EU) 1 records
StatusNameEC NumberLink
Registered1-[(2,4-dinitrophenyl)azo]-2-naphthol222-429-4ECHA overview →

Australian Status (AICIS)

Australian industrial chemicals inventory status and applicable conditions.

SOURCE AICIS inventory 1 records
Inventory Status
listed

Cosmetic Safety Profile

Same-CAS cosmetic ingredient record for cross-vertical context.

SOURCE CosIng / Ingredients DB
EU Status
permitted
Max
-
Category
Colorant
View full cosmetic safety profile →

Frequently Asked Questions

What is the NOAEL for C.I. Pigment Orange 5?

C.I. Pigment Orange 5 has 7 NOAEL studies in the database. The lowest reported value is cancer listing type. Source: California Proposition 65.

What regulatory lists include C.I. Pigment Orange 5?

C.I. Pigment Orange 5 appears on 6 regulatory/inventory lists including Arts and crafts/Office supplies - body paint - tattoo ink; Europe, inert_ingredient; non_food_use; Pesticides, banned; Europe; Personal care, and 3 more. Source: EPA CPDat.

Is C.I. Pigment Orange 5 on the California Proposition 65 list?

Yes, C.I. Pigment Orange 5 is listed under California Proposition 65 for cancer. Source: California OEHHA Proposition 65.

Is C.I. Pigment Orange 5 used in cosmetics?

Yes, C.I. Pigment Orange 5 is also indexed as a cosmetic ingredient under the name CI 12480. View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.

Where does the safety data for C.I. Pigment Orange 5 come from?

Safety data is sourced from EPA ToxValDB, EPA CPDat, AICIS (Australian Industrial Chemicals Introduction Scheme), EPA DSSTox, ECHA REACH, California Proposition 65, CosIng / Ingredients DB. All data traces to primary regulatory sources and is updated from official government databases.

Is C.I. Pigment Orange 5 used outside industrial chemicals?

C.I. Pigment Orange 5 also appears in cosmetics databases.