NOAEL Data Cosmetic Ingredient

Palmatine

Also known as: Dibenzo[a,g]quinolizinium, 5,6-dihydro-2,3,9,10-tetramethoxy-, 2,3,9,10-Tetramethoxy-5,6-dihydroisoquinolino[2,1-b]isoquinolin-7-ium, 5,6-Dihydro-2,3,9,10-tetramethoxydibenzo[a,g]quinolizinium, O,O-Dimethyldemethyleneberberine, Berbericinine (+12 more)

CAS 3486-67-7

Palmatine (CAS 3486-67-7) is a chemical substance. Key regulatory status: cosmetic ingredient cross-reference; source data from EPA ToxValDB, EPA CPDat.

View cosmetic safety profile for PALMATINE →

SOURCE noael studies public
NOAEL studies
4
SOURCE chemical inventory jurisdictions
Regulatory lists
0
SOURCE eu clp annex vi
GHS signal
Not classified

Chemical Identity

CAS, identifiers, formula, and alternate names for the matched substance record.

SOURCE DSSTox identifiers 23 fields
Name
Palmatine
CAS Number
3486-67-7
DTXSID
DTXSID9048065
Molecular Formula
C21H22NO4
InChI Key
QUCQEUCGKKTEBI-UHFFFAOYSA-N
Monoisotopic Mass
352.154883
Synonyms
Dibenzo[a,g]quinolizinium, 5,6-dihydro-2,3,9,10-tetramethoxy-2,3,9,10-Tetramethoxy-5,6-dihydroisoquinolino[2,1-b]isoquinolin-7-ium5,6-Dihydro-2,3,9,10-tetramethoxydibenzo[a,g]quinoliziniumO,O-DimethyldemethyleneberberineBerbericinineBerbinium, 7,8,13,13a-tetradehydro-2,3,9,10-tetramethoxy-DepilineFibrauretinFibrauretineHuang Teng Su5-21-06-00202BRN 1555498

Functional Uses

Industrial and product-use categories associated with this substance.

SOURCE EPA CPDat 4 records
Antioxidant

NOAEL Studies

Toxicology endpoints rendered from public NOAEL study rows.

SOURCE NOAEL studies Showing 4 of 4 studies
ValueUnitEndpointRouteSpeciesSource
G50C034217UNIIFDA UNII substance identifier--openFDA substances
G50C034217UNIIFDA UNII substance identifier--openFDA substances
G50C034217UNIIFDA UNII substance identifier--openFDA substances
G50C034217UNIIFDA UNII substance identifier--openFDA substances

Showing 4 of 4 studies

Cosmetic Safety Profile

Same-CAS cosmetic ingredient record for cross-vertical context.

SOURCE CosIng / Ingredients DB
EU Status
permitted
Max
-
Category
Antioxidant
View full cosmetic safety profile →

Pharmaceutical Data

Same-CAS pharmaceutical records from drug and bioactivity sources.

SOURCE EMBL-EBI ChEMBL PALMITINE
ChEMBL Phase
Not listed
Adverse Events
0
Bioactivity
5
View full pharmaceutical profile →

Frequently Asked Questions

What is the NOAEL for Palmatine?

Palmatine has 4 NOAEL studies in the database. The lowest reported value is G50C034217 UNII. Source: openFDA substances.

Is Palmatine used in cosmetics?

Yes, Palmatine is also indexed as a cosmetic ingredient under the name PALMATINE. View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.

Where does the safety data for Palmatine come from?

Safety data is sourced from EPA ToxValDB, EPA CPDat, EPA DSSTox, CosIng / Ingredients DB, ChEMBL / DailyMed. All data traces to primary regulatory sources and is updated from official government databases.

Is Palmatine used outside industrial chemicals?

Palmatine also appears in cosmetics, pharmaceutical databases.