What is the NOAEL for Ipriflavone?
Ipriflavone has 6 NOAEL studies in the database. The lowest reported value is 80BJ7WN25Z UNII. Source: openFDA substances.
NOAEL Data
Cosmetic Ingredient
Ipriflavone
Also known as: BRN 4754346, Ipriflavona, Ipriflavonum, UNII-80BJ7WN25Z, 7-(1-methylethoxy)-3-phenyl-4H-1-benzopyran-4-one (+2 more)
CAS 35212-22-7
Ipriflavone (CAS 35212-22-7) is a chemical substance. Key regulatory status: 2 regulatory/inventory lists, cosmetic ingredient cross-reference; source data from EPA ToxValDB, EPA CPDat.
SOURCE
NOAEL studies
NOAEL studies
6
SOURCE
Chemical inventory jurisdictions
Regulatory lists
2
SOURCE
EU CLP Annex VI
GHS signal
Not classified
Chemical Identity
CAS, identifiers, formula, and alternate names for the matched substance record.
SOURCE
DSSTox identifiers
12 fields
Name
Ipriflavone
CAS Number
35212-22-7
Molecular Formula
C18H16O3
InChI Key
SFBODOKJTYAUCM-UHFFFAOYSA-N
Monoisotopic Mass
280.109944
Synonyms
BRN 4754346IpriflavonaIpriflavonumUNII-80BJ7WN25Z7-(1-methylethoxy)-3-phenyl-4H-1-benzopyran-4-one7-isopropoxyisoflavoneFL-113
Regulatory Lists
Inventory, screening, and regulatory list matches from public chemical databases.
SOURCE
EPA CPDat
2 records
| List | Keyword | Source |
|---|---|---|
| pharmaceutical | US International Trade Commission | CPCat |
| Canada; pharmaceutical | DrugBank | DrugBank |
NOAEL Studies
Toxicology endpoints rendered from public NOAEL study rows.
SOURCE
NOAEL studies
Showing 6 of 6 studies
| Value | Unit | Endpoint | Route | Species | Source |
|---|---|---|---|---|---|
| 80BJ7WN25Z | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| >2500 | mg/kg bw | LD50 | oral | Rat | NTP ICE acute oral |
| =200 | mg/day | LEL | oral | Rat | ToxValDB Uterotrophic Hershberger DB |
| 200 | mg/day | LOEL | Oral | Rat | NTP ICE endocrine |
| >3000 | mg/kg bw/day | NOEL | oral | Rat | ToxValDB HESS |
| 30 | % | Uterine weight increase vs control | Oral | Rat | NTP ICE endocrine |
Showing 6 of 6 studies
Cosmetic Safety Profile
Same-CAS cosmetic ingredient record for cross-vertical context.
SOURCE
CosIng / Ingredients DB
EU Status
permitted
Max
-
Category
Vitamins
Pharmaceutical Data
Same-CAS pharmaceutical records from drug and bioactivity sources.
SOURCE
ChEMBL / DailyMed
IPRIFLAVONE
ChEMBL Phase
2
Adverse Events
2
Bioactivity
7
Frequently Asked Questions
What regulatory lists include Ipriflavone?
Ipriflavone appears on 2 regulatory/inventory lists including pharmaceutical, Canada; pharmaceutical. Source: EPA CPDat.
Is Ipriflavone used in cosmetics?
Yes, Ipriflavone is also indexed as a cosmetic ingredient under the name Ipriflavone. View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.
Where does the safety data for Ipriflavone come from?
Safety data is sourced from EPA ToxValDB, EPA CPDat, EPA DSSTox, CosIng / Ingredients DB, ChEMBL / DailyMed. All data traces to primary regulatory sources and is updated from official government databases.
Is Ipriflavone used outside industrial chemicals?
Ipriflavone also appears in cosmetics, pharmaceutical databases.