Also known as: EINECS 223-242-0, (2,4,6-Trioxotriazine-1,3,5(2H,4H,6H)-triyl)tris(hexamethylene) isocyanate, (2,4,6-trioxotriazine-1,3,5(2H,4H,6H)-triyl)tris(hexamethyleneisocyanate), 1,3,5-tris(6-isocyanatohexyl)-1,3,5-triazine-2,4,6 (1H,3H,5H)-trione, 1,3,5-tris(isocyanatohexamethylene)isocyanurate (+5 more)
CAS 3779-63-3
1,3,5-Triazine-2,4,6(1H,3H,5H)-trione, 1,3,5-tris(6-isocyanatohexyl)- (CAS 3779-63-3) is a chemical substance. Key regulatory status: REACH registered, cosmetic ingredient cross-reference; source data from EPA ToxValDB, EPA CPDat, AICIS, ECHA REACH.
1,3,5-Triazine-2,4,6(1H,3H,5H)-trione, 1,3,5-tris(6-isocyanatohexyl)- is prohibited in EU cosmetics but has active industrial GHS classifications (H317, H332, H335).
CAS, identifiers, formula, and alternate names for the matched substance record.
Industrial and product-use categories associated with this substance.
Toxicology endpoints rendered from public NOAEL study rows.
| Value | Unit | Endpoint | Route | Species | Source |
|---|---|---|---|---|---|
| =0.5 | mg/m3 | DNEL local | inhalation | Human | ToxValDB_GESTIS_DNEL |
| DE5PQE5835 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| DE5PQE5835 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| DE5PQE5835 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| DE5PQE5835 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| =0.0004 | mg/m3 | RfC | inhalation | Human | ToxValDB_RSL |
Showing 6 of 6 studies
Registration status from the ECHA REACH registered substances database.
| Status | Name | EC Number | Link |
|---|---|---|---|
| Registered | (2,4,6-trioxotriazine-1,3,5(2H,4H,6H)-triyl)tris(hexamethylene) isocyanate | 223-242-0 | ECHA overview → |
Australian industrial chemicals inventory status and applicable conditions.
Same-CAS cosmetic ingredient record for cross-vertical context.
1,3,5-Triazine-2,4,6(1H,3H,5H)-trione, 1,3,5-tris(6-isocyanatohexyl)- has 6 NOAEL studies in the database. The lowest reported value is 0.5 mg/m3 via inhalation in Human. Source: ToxValDB_GESTIS_DNEL.
Yes, 1,3,5-Triazine-2,4,6(1H,3H,5H)-trione, 1,3,5-tris(6-isocyanatohexyl)- is also indexed as a cosmetic ingredient under the name HDI Isocyanurate Trimer. View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.
Safety data is sourced from EPA ToxValDB, EPA CPDat, AICIS (Australian Industrial Chemicals Introduction Scheme), EPA DSSTox, ECHA REACH, CosIng / Ingredients DB. All data traces to primary regulatory sources and is updated from official government databases.
1,3,5-Triazine-2,4,6(1H,3H,5H)-trione, 1,3,5-tris(6-isocyanatohexyl)- is prohibited in EU cosmetics but has active industrial GHS classifications (H317, H332, H335).
1,3,5-Triazine-2,4,6(1H,3H,5H)-trione, 1,3,5-tris(6-isocyanatohexyl)- also appears in cosmetics databases.