NOAEL Data REACH Registered Cosmetic Ingredient

1,3,3,5-Tetramethyl-1,1,5,5-tetraphenyltrisiloxane

Also known as: 1,1,5,5-Tetraphenyl-1,3,3,5-tetramethyltrisiloxane, Trisiloxane, 1,3,3,5-tetramethyl-1,1,5,5-tetraphenyl-, EINECS 223-620-5, UNII-6IOT4Y7V2B

CAS 3982-82-9

1,3,3,5-Tetramethyl-1,1,5,5-tetraphenyltrisiloxane (CAS 3982-82-9) is a chemical substance. Key regulatory status: REACH registered, 1 regulatory/inventory list, cosmetic ingredient cross-reference; source data from EPA ToxValDB, EPA CPDat, AICIS, ECHA REACH.

View cosmetic safety profile for Tetramethyl Tetraphenyl Trisiloxane →

SOURCE noael studies public

NOAEL studies

SOURCE chemical inventory jurisdictions

Regulatory lists

SOURCE eu clp annex vi

GHS signal

Not classified

Chemical Identity

CAS, identifiers, formula, and alternate names for the matched substance record.

SOURCE DSSTox identifiers 10 fields

Name

1,3,3,5-Tetramethyl-1,1,5,5-tetraphenyltrisiloxane

CAS Number

3982-82-9

DTXSID

DTXSID2052073

Molecular Formula

C28H32O2Si3

InChI Key

YFCVAZGXPLMNDG-UHFFFAOYSA-N

Monoisotopic Mass

484.17101

Synonyms

1,1,5,5-Tetraphenyl-1,3,3,5-tetramethyltrisiloxaneTrisiloxane, 1,3,3,5-tetramethyl-1,1,5,5-tetraphenyl-EINECS 223-620-5UNII-6IOT4Y7V2B

Functional Uses

Industrial and product-use categories associated with this substance.

SOURCE EPA CPDat 2 records

Softener and conditioner

Regulatory Lists

Inventory, screening, and regulatory list matches from public chemical databases.

SOURCE EPA CPDat 1 records

List	Keyword	Source
inert_ingredient; non_food_use; Pesticides	EPA	CPCat

NOAEL Studies

Toxicology endpoints rendered from public NOAEL study rows.

SOURCE NOAEL studies Showing 4 of 4 studies

Value	Unit	Endpoint	Route	Species	Source
6IOT4Y7V2B	UNII	FDA UNII substance identifier	-	-	openFDA substances
6IOT4Y7V2B	UNII	FDA UNII substance identifier	-	-	openFDA substances
6IOT4Y7V2B	UNII	FDA UNII substance identifier	-	-	openFDA substances
6IOT4Y7V2B	UNII	FDA UNII substance identifier	-	-	openFDA substances

Showing 4 of 4 studies

REACH Registration

Registration status from the ECHA REACH registered substances database.

SOURCE ECHA (EU) 1 records

Status	Name	EC Number	Link
Registered	1,3,3,5-tetramethyl-1,1,5,5-tetraphenyltrisiloxane	223-620-5	ECHA overview →

Australian Status (AICIS)

Australian industrial chemicals inventory status and applicable conditions.

SOURCE AICIS inventory 1 records

Inventory Status

listed

Cosmetic Safety Profile

Same-CAS cosmetic ingredient record for cross-vertical context.

SOURCE CosIng / Ingredients DB

EU Status

restricted

Max

Frequently Asked Questions

What is the NOAEL for 1,3,3,5-Tetramethyl-1,1,5,5-tetraphenyltrisiloxane?

1,3,3,5-Tetramethyl-1,1,5,5-tetraphenyltrisiloxane has 4 NOAEL studies in the database. The lowest reported value is 6IOT4Y7V2B UNII. Source: openFDA substances.

What regulatory lists include 1,3,3,5-Tetramethyl-1,1,5,5-tetraphenyltrisiloxane?

1,3,3,5-Tetramethyl-1,1,5,5-tetraphenyltrisiloxane appears on 1 regulatory/inventory list including inert_ingredient; non_food_use; Pesticides. Source: EPA CPDat.

Is 1,3,3,5-Tetramethyl-1,1,5,5-tetraphenyltrisiloxane used in cosmetics?

Yes, 1,3,3,5-Tetramethyl-1,1,5,5-tetraphenyltrisiloxane is also indexed as a cosmetic ingredient under the name Tetramethyl Tetraphenyl Trisiloxane. View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.

Where does the safety data for 1,3,3,5-Tetramethyl-1,1,5,5-tetraphenyltrisiloxane come from?

Safety data is sourced from EPA ToxValDB, EPA CPDat, AICIS (Australian Industrial Chemicals Introduction Scheme), EPA DSSTox, ECHA REACH, CosIng / Ingredients DB. All data traces to primary regulatory sources and is updated from official government databases.

Is 1,3,3,5-Tetramethyl-1,1,5,5-tetraphenyltrisiloxane used outside industrial chemicals?

1,3,3,5-Tetramethyl-1,1,5,5-tetraphenyltrisiloxane also appears in cosmetics databases.