What is the NOAEL for Silicon carbide?
Silicon carbide has 7 NOAEL studies in the database. The lowest reported value is WXQ6E537EW UNII. Source: openFDA substances.
NOAEL Data
IARC Group 2A
REACH Registered
Cosmetic Ingredient
Silicon carbide
Also known as: SiC, Silicon carbide (SiC), Carbolon, Carborundeum, Crystar (+7 more)
CAS 409-21-2
Silicon carbide (CAS 409-21-2) is a chemical substance; key hazard signal: IARC Group 2A. Key regulatory status: REACH registered, 3 regulatory/inventory lists, cosmetic ingredient cross-reference; source data from EPA ToxValDB, EPA CPDat, AICIS, IARC, ECHA REACH, ILO ICSC, OSHA.
Cross-Vertical Regulatory Divergence
Silicon carbide is classified GHS Danger (H350i, H372, H350, H370, H225, H315, H319, H335) in the chemicals database but is allowed in EU cosmetics.
SOURCE
Cross-vertical comparison
Cosmetics: ingredients.eu_status; Chemicals: ghs_classifications.signal_word/hazard_statement_code
SOURCE
noael studies public
NOAEL studies
7
SOURCE
chemical inventory jurisdictions
Regulatory lists
3
SOURCE
eu clp annex vi
GHS signal
Not classified
Chemical Identity
CAS, identifiers, formula, and alternate names for the matched substance record.
SOURCE
DSSTox identifiers
18 fields
Name
Silicon carbide
CAS Number
409-21-2
DTXSID
DTXSID5052751
Molecular Formula
CSi
InChI Key
HBMJWWWQQXIZIP-UHFFFAOYSA-N
Monoisotopic Mass
39.976927
Synonyms
SiCSilicon carbide (SiC)CarbolonCarborundeumCrystarEINECS 206-991-8NicalonSC 9UNII-WXQ6E537EWSiliziumkarbid[SiC]silicon(IV) carbide
IARC Carcinogen Classification
Carcinogenic hazard classification from IARC monograph evaluations.
SOURCE
IARC Monographs on the Identification of Carcinogenic Hazards to Humans
1 records
| Group | Meaning | Evaluated | Volume |
|---|---|---|---|
| Group 2A | Probably carcinogenic | 2014 | 111 |
ICSC Chemical Safety
International Chemical Safety Card hazard and exposure summary.
SOURCE
ILO/WHO International Chemical Safety Cards
1 records
| Field | Value |
|---|---|
| Short-term Effects | May cause mechanical irritation. |
OSHA Exposure Limits
Occupational exposure limits from OSHA, NIOSH, and ACGIH rows.
SOURCE
OSHA / NIOSH / ACGIH occupational exposure limits
4 records
| Agency | Metric | Value | ppm | mg/m3 | Skin |
|---|---|---|---|---|---|
| OSHA | TWA | 15 mg/m³ (total dust), 5 mg/m³ (respirable fraction) | - | 15 | N |
| NIOSH | TWA | 10 mg/m³ (total dust), 5 mg/m³ (resp) | - | 10 | N |
| ACGIH | TWA | Nonfibrous: 10 mg/m³ (inhalable particulate matter), 3 mg/m³ (respirable particulate matter) *The values are for particulate matter containing no asbestos and <1% crystalline silica. Fibrous (including whiskers): 0.1 f/cc (respirable fibers), see footnote [F] in the TLV booklet. [2002] | - | 10 | N |
| CAL/OSHA | TWA | 10 mg/m³ (total dust), 5 mg/m³ (respirable fraction) | - | 10 | N |
Functional Uses
Industrial and product-use categories associated with this substance.
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EPA CPDat
7 records
AbrasiveProcessing aids not otherwise specifiedFiller
Regulatory Lists
Inventory, screening, and regulatory list matches from public chemical databases.
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EPA CPDat
3 records
| List | Keyword | Source |
|---|---|---|
| drinking_water; Europe; manufacturing; plastic_additive | Belgaqua | CPCat |
| active_ingredient; Australia | Australian Pesticides and Veterinary Medicines Authority | CPCat |
| SCIL (9/2019) | USEPA | Safer Chemical Ingredients List |
NOAEL Studies
Toxicology endpoints rendered from public NOAEL study rows.
SOURCE
NOAEL studies
Showing 7 of 7 studies
| Value | Unit | Endpoint | Route | Species | Source |
|---|---|---|---|---|---|
| WXQ6E537EW | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| WXQ6E537EW | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| WXQ6E537EW | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| WXQ6E537EW | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 2A | IARC group | IARC carcinogenicity classification | - | - | IARC Monographs |
| 2 | unitless | IARC group | - | - | NTP_ICE_cancer |
| =2000 | mg/kg bw | LD50 | oral | Rat | NTP_ICE_acute_oral |
Showing 7 of 7 studies
REACH Registration
Registration status from the ECHA REACH registered substances database.
SOURCE
ECHA (EU)
1 records
| Status | Name | EC Number | Link |
|---|---|---|---|
| Registered | Silicon carbide | 206-991-8 | ECHA overview → |
Australian Status (AICIS)
Australian industrial chemicals inventory status and applicable conditions.
SOURCE
AICIS inventory
1 records
Inventory Status
listed
Cosmetic Safety Profile
Same-CAS cosmetic ingredient record for cross-vertical context.
SOURCE
CosIng / Ingredients DB
EU Status
permitted
Max
-
Category
Skin Conditioning
Frequently Asked Questions
What regulatory lists include Silicon carbide?
Silicon carbide appears on 3 regulatory/inventory lists including drinking_water; Europe; manufacturing; plastic_additive, active_ingredient; Australia, SCIL (9/2019). Source: EPA CPDat.
Is Silicon carbide a carcinogen according to IARC?
Silicon carbide is classified by IARC as Group 2A — probably carcinogenic to humans (evaluated 2014). Source: IARC Monographs on the Identification of Carcinogenic Hazards to Humans.
What are the occupational exposure limits for Silicon carbide?
Occupational exposure limits for Silicon carbide are set by OSHA, NIOSH, ACGIH. 4 limit values from official agencies are documented in the database. Source: OSHA, NIOSH, ACGIH.
Is Silicon carbide used in cosmetics?
Yes, Silicon carbide is also indexed as a cosmetic ingredient under the name Silicon Carbide. View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.
Where does the safety data for Silicon carbide come from?
Safety data is sourced from EPA ToxValDB, EPA CPDat, AICIS (Australian Industrial Chemicals Introduction Scheme), EPA DSSTox, IARC Monographs, ECHA REACH, ILO/WHO ICSC, OSHA/NIOSH/ACGIH, CosIng / Ingredients DB. All data traces to primary regulatory sources and is updated from official government databases.
Does Silicon carbide have different safety status in cosmetics vs industrial chemicals?
Silicon carbide is classified GHS Danger (H350i, H372, H350, H370, H225, H315, H319, H335) in the chemicals database but is allowed in EU cosmetics.
Is Silicon carbide used outside industrial chemicals?
Silicon carbide also appears in cosmetics databases.