NOAEL Data REACH Registered Cosmetic Ingredient

Diethyl pyridine-2,4-dicarboxylate

Also known as: Diethyl 2,4-pyridinedicarboxylate, Mexoryl SBU

CAS 41438-38-4

Diethyl pyridine-2,4-dicarboxylate (CAS 41438-38-4) is a chemical substance. Key regulatory status: REACH registered, cosmetic ingredient cross-reference; source data from EPA ToxValDB, EPA CPDat, AICIS, ECHA REACH.

View cosmetic safety profile for Stemoxydine →

SOURCE noael studies public
NOAEL studies
6
SOURCE chemical inventory jurisdictions
Regulatory lists
0
SOURCE eu clp annex vi
GHS signal
Not classified

Chemical Identity

CAS, identifiers, formula, and alternate names for the matched substance record.

SOURCE DSSTox identifiers 8 fields
Name
Diethyl pyridine-2,4-dicarboxylate
CAS Number
41438-38-4
DTXSID
DTXSID00961682
Molecular Formula
C11H13NO4
InChI Key
MUUDQLHCIAOWPR-UHFFFAOYSA-N
Monoisotopic Mass
223.084458
Synonyms
Diethyl 2,4-pyridinedicarboxylateMexoryl SBU

Functional Uses

Industrial and product-use categories associated with this substance.

SOURCE EPA CPDat 2 records
Softener and conditioner

NOAEL Studies

Toxicology endpoints rendered from public NOAEL study rows.

SOURCE NOAEL studies Showing 6 of 6 studies
ValueUnitEndpointRouteSpeciesSource
=4.29mg/m3DNEL systemicinhalationHumanToxValDB_GESTIS_DNEL
4SN4572M5SUNIIFDA UNII substance identifier--openFDA substances
4SN4572M5SUNIIFDA UNII substance identifier--openFDA substances
4SN4572M5SUNIIFDA UNII substance identifier--openFDA substances
4SN4572M5SUNIIFDA UNII substance identifier--openFDA substances
>2000mg/kg bwLD50oralRatNTP_ICE_acute_oral

Showing 6 of 6 studies

REACH Registration

Registration status from the ECHA REACH registered substances database.

SOURCE ECHA (EU) 1 records
StatusNameEC NumberLink
Registered2,4-Pyridinedicarboxylic acid, diethyl ester680-341-5ECHA overview →

Australian Status (AICIS)

Australian industrial chemicals inventory status and applicable conditions.

SOURCE AICIS inventory 1 records
Inventory Status
listed_with_terms
Conditions
Specific information requirements: Obligations to provide information apply. These obligations are: 1. A person introducing this chemical must tell us in writing within 28 calendar days if any of the following circumstances have occurred in relation to their introduction (importation or manufacture): a. the introduction volume of the chemical exceeds 1 tonne per annum; b. the concentration of the chemical exceeds or is intended to exceed 10% in hair care cosmetic products. 2. A person who introduces this chemical must tell us in writing within 28 calendar days if they become aware of any of the following circumstances, namely, that since the assessment under the Industrial Chemicals (Notification and Assessment) Act 1989: a. the function or use of the chemical has changed, or is likely to change, significantly; b. the amount of the chemical being introduced has increased, or is likely to increase, significantly; c. in the case of a chemical not manufactured, or proposed to be manufactured, in Australia at the time of the assessment—it has begun to be manufactured in Australia; d. the method of manufacture of the chemical in Australia has changed, or is likely to change, in a way that may result in an increased risk of an adverse effect of the chemical on occupational health and safety, public health or the environment; e. additional information has become available to the person as to an adverse effect of the chemical on occupational health and safety, public health or the environment.

Cosmetic Safety Profile

Same-CAS cosmetic ingredient record for cross-vertical context.

SOURCE CosIng / Ingredients DB
EU Status
permitted
Max
-
Category
active
View full cosmetic safety profile →

Frequently Asked Questions

What is the NOAEL for Diethyl pyridine-2,4-dicarboxylate?

Diethyl pyridine-2,4-dicarboxylate has 6 NOAEL studies in the database. The lowest reported value is 4.29 mg/m3 via inhalation in Human. Source: ToxValDB_GESTIS_DNEL.

Is Diethyl pyridine-2,4-dicarboxylate used in cosmetics?

Yes, Diethyl pyridine-2,4-dicarboxylate is also indexed as a cosmetic ingredient under the name Stemoxydine. View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.

Where does the safety data for Diethyl pyridine-2,4-dicarboxylate come from?

Safety data is sourced from EPA ToxValDB, EPA CPDat, AICIS (Australian Industrial Chemicals Introduction Scheme), EPA DSSTox, ECHA REACH, CosIng / Ingredients DB. All data traces to primary regulatory sources and is updated from official government databases.

Is Diethyl pyridine-2,4-dicarboxylate used outside industrial chemicals?

Diethyl pyridine-2,4-dicarboxylate also appears in cosmetics databases.