What is the NOAEL for 2,2,4,4,6,8,8-Heptamethylnonane?
2,2,4,4,6,8,8-Heptamethylnonane has 5 NOAEL studies in the database. The lowest reported value is 8LP0677305 UNII. Source: openFDA substances.
NOAEL Data
REACH Registered
Cosmetic Ingredient
2,2,4,4,6,8,8-Heptamethylnonane
Also known as: EINECS 224-506-8, UNII-918X1OUF1E, heptamethylnonane, isocetane
CAS 4390-04-9
2,2,4,4,6,8,8-Heptamethylnonane (CAS 4390-04-9) is a chemical substance. Key regulatory status: REACH registered, 1 regulatory/inventory list, cosmetic ingredient cross-reference; source data from EPA ToxValDB, EPA CPDat, AICIS, ECHA REACH.
Cross-Vertical Regulatory Divergence
2,2,4,4,6,8,8-Heptamethylnonane is classified GHS Danger (H301, H304, H311, H315, H319, H350) in the chemicals database but is allowed in EU cosmetics.
SOURCE
Cross-vertical comparison
Cosmetics: ingredients.eu_status; Chemicals: ghs_classifications.signal_word/hazard_statement_code
SOURCE
noael studies public
NOAEL studies
5
SOURCE
chemical inventory jurisdictions
Regulatory lists
1
SOURCE
eu clp annex vi
GHS signal
Not classified
Chemical Identity
CAS, identifiers, formula, and alternate names for the matched substance record.
SOURCE
DSSTox identifiers
10 fields
Name
2,2,4,4,6,8,8-Heptamethylnonane
CAS Number
4390-04-9
DTXSID
DTXSID7052101
Molecular Formula
C16H34
InChI Key
VCLJODPNBNEBKW-UHFFFAOYSA-N
Monoisotopic Mass
226.266051
Synonyms
EINECS 224-506-8UNII-918X1OUF1Eheptamethylnonaneisocetane
Functional Uses
Industrial and product-use categories associated with this substance.
SOURCE
EPA CPDat
1 records
Fragrance
Regulatory Lists
Inventory, screening, and regulatory list matches from public chemical databases.
SOURCE
EPA CPDat
1 records
| List | Keyword | Source |
|---|---|---|
| IFRA Transparency | IFRA | IFRA |
NOAEL Studies
Toxicology endpoints rendered from public NOAEL study rows.
SOURCE
NOAEL studies
Showing 5 of 5 studies
| Value | Unit | Endpoint | Route | Species | Source |
|---|---|---|---|---|---|
| 8LP0677305 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 8LP0677305 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 8LP0677305 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 8LP0677305 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| >5000 | mg/kg bw | LD50 | oral | Rat | NTP_ICE_acute_oral |
Showing 5 of 5 studies
REACH Registration
Registration status from the ECHA REACH registered substances database.
SOURCE
ECHA (EU)
1 records
| Status | Name | EC Number | Link |
|---|---|---|---|
| Registered | 2,2,4,4,6,8,8-heptamethylnonane | 224-506-8 | ECHA overview → |
Australian Status (AICIS)
Australian industrial chemicals inventory status and applicable conditions.
SOURCE
AICIS inventory
1 records
Inventory Status
listed
Cosmetic Safety Profile
Same-CAS cosmetic ingredient record for cross-vertical context.
SOURCE
CosIng / Ingredients DB
EU Status
permitted
Max
-
Category
emollient
Pharmaceutical Data
Same-CAS pharmaceutical records from drug and bioactivity sources.
SOURCE
EMBL-EBI ChEMBL
CHEMBL3561882
ChEMBL Phase
Not listed
Adverse Events
0
Bioactivity
0
Frequently Asked Questions
What regulatory lists include 2,2,4,4,6,8,8-Heptamethylnonane?
2,2,4,4,6,8,8-Heptamethylnonane appears on 1 regulatory/inventory list including IFRA Transparency. Source: EPA CPDat.
Is 2,2,4,4,6,8,8-Heptamethylnonane used in cosmetics?
Yes, 2,2,4,4,6,8,8-Heptamethylnonane is also indexed as a cosmetic ingredient under the name Isohexadecane. View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.
Where does the safety data for 2,2,4,4,6,8,8-Heptamethylnonane come from?
Safety data is sourced from EPA ToxValDB, EPA CPDat, AICIS (Australian Industrial Chemicals Introduction Scheme), EPA DSSTox, ECHA REACH, CosIng / Ingredients DB, ChEMBL / DailyMed. All data traces to primary regulatory sources and is updated from official government databases.
Does 2,2,4,4,6,8,8-Heptamethylnonane have different safety status in cosmetics vs industrial chemicals?
2,2,4,4,6,8,8-Heptamethylnonane is classified GHS Danger (H301, H304, H311, H315, H319, H350) in the chemicals database but is allowed in EU cosmetics.
Is 2,2,4,4,6,8,8-Heptamethylnonane used outside industrial chemicals?
2,2,4,4,6,8,8-Heptamethylnonane also appears in cosmetics, pharmaceutical databases.