NOAEL Data Cosmetic Ingredient

Butylene carbonate

Also known as: 1,3-Dioxolan-2-one, 4-ethyl-, Carbonic acid, ethylethylene ester, 1,2-Butylene carbonate, 2-Oxo-4-ethyl-1,3-dioxolane, 1,2-Butanediol, cyclic carbonate (+5 more)

CAS 4437-85-8

Butylene carbonate (CAS 4437-85-8) is a chemical substance. Key regulatory status: 2 regulatory/inventory lists, cosmetic ingredient cross-reference; source data from EPA ToxValDB, EPA CPDat.

View cosmetic safety profile for Butylene Carbonate →

SOURCE noael studies public
NOAEL studies
6
SOURCE chemical inventory jurisdictions
Regulatory lists
2
SOURCE eu clp annex vi
GHS signal
Not classified

Chemical Identity

CAS, identifiers, formula, and alternate names for the matched substance record.

SOURCE DSSTox identifiers 16 fields
Name
Butylene carbonate
CAS Number
4437-85-8
DTXSID
DTXSID9040342
Molecular Formula
C5H8O3
InChI Key
ZZXUZKXVROWEIF-UHFFFAOYSA-N
Monoisotopic Mass
116.047344
Synonyms
1,3-Dioxolan-2-one, 4-ethyl-Carbonic acid, ethylethylene ester1,2-Butylene carbonate2-Oxo-4-ethyl-1,3-dioxolane1,2-Butanediol, cyclic carbonate4-19-00-01571BRN 0108553Carbonic acid, cyclic ethylethylene ester4-Ethyl-1,3-dioxolan-2-oneUNII-I64G2S50OV

Functional Uses

Industrial and product-use categories associated with this substance.

SOURCE EPA CPDat 2 records
Softener and conditionerSolvent

Regulatory Lists

Inventory, screening, and regulatory list matches from public chemical databases.

SOURCE EPA CPDat 2 records
ListKeywordSource
SCIL (9/2019)USEPASafer Chemical Ingredients List
inert_ingredient; non_food_use; PesticidesEPACPCat

NOAEL Studies

Toxicology endpoints rendered from public NOAEL study rows.

SOURCE NOAEL studies Showing 6 of 6 studies
ValueUnitEndpointRouteSpeciesSource
I64G2S50OVUNIIFDA UNII substance identifier--openFDA substances
I64G2S50OVUNIIFDA UNII substance identifier--openFDA substances
I64G2S50OVUNIIFDA UNII substance identifier--openFDA substances
I64G2S50OVUNIIFDA UNII substance identifier--openFDA substances
>5000mg/kg bwLD50oralRatNTP_ICE_acute_oral
-unitlessModel Score--NTP_ICE_endocrine

Showing 6 of 6 studies

Cosmetic Safety Profile

Same-CAS cosmetic ingredient record for cross-vertical context.

SOURCE CosIng / Ingredients DB
EU Status
permitted
Max
-
Category
Skin Conditioning
View full cosmetic safety profile →

Frequently Asked Questions

What is the NOAEL for Butylene carbonate?

Butylene carbonate has 6 NOAEL studies in the database. The lowest reported value is I64G2S50OV UNII. Source: openFDA substances.

What regulatory lists include Butylene carbonate?

Butylene carbonate appears on 2 regulatory/inventory lists including SCIL (9/2019), inert_ingredient; non_food_use; Pesticides. Source: EPA CPDat.

Is Butylene carbonate used in cosmetics?

Yes, Butylene carbonate is also indexed as a cosmetic ingredient under the name Butylene Carbonate. View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.

Where does the safety data for Butylene carbonate come from?

Safety data is sourced from EPA ToxValDB, EPA CPDat, EPA DSSTox, CosIng / Ingredients DB. All data traces to primary regulatory sources and is updated from official government databases.

Is Butylene carbonate used outside industrial chemicals?

Butylene carbonate also appears in cosmetics databases.