NOAEL Data Cosmetic Ingredient

Propanedioic acid, 2-[(4-hydroxy-3,5-dimethoxyphenyl)methylene]-, 1,3-bis(2-ethylhexyl) ester

Also known as: Diethylhexyl syringylidenemalonate, 1,3-bis(2-ethylhexyl) 2-[(4-hydroxy-3,5-dimethoxyphenyl)methylidene]propanedioate, Oxynex ST

CAS 444811-29-4

Propanedioic acid, 2-[(4-hydroxy-3,5-dimethoxyphenyl)methylene]-, 1,3-bis(2-ethylhexyl) ester (CAS 444811-29-4) is a chemical substance. Key regulatory status: cosmetic ingredient cross-reference; source data from EPA ToxValDB, EPA CPDat.

View cosmetic safety profile for Diethylhexyl Syringylidenemalonate →

SOURCE noael studies public
NOAEL studies
5
SOURCE chemical inventory jurisdictions
Regulatory lists
0
SOURCE eu clp annex vi
GHS signal
Not classified

Chemical Identity

CAS, identifiers, formula, and alternate names for the matched substance record.

SOURCE DSSTox identifiers 9 fields
Name
Propanedioic acid, 2-[(4-hydroxy-3,5-dimethoxyphenyl)methylene]-, 1,3-bis(2-ethylhexyl) ester
CAS Number
444811-29-4
DTXSID
DTXSID301021563
Molecular Formula
C28H44O7
InChI Key
NSBAXYINVVKQQI-UHFFFAOYNA-N
Monoisotopic Mass
492.308704
Synonyms
Diethylhexyl syringylidenemalonate1,3-bis(2-ethylhexyl) 2-[(4-hydroxy-3,5-dimethoxyphenyl)methylidene]propanedioateOxynex ST

Functional Uses

Industrial and product-use categories associated with this substance.

SOURCE EPA CPDat 3 records
Humectant

NOAEL Studies

Toxicology endpoints rendered from public NOAEL study rows.

SOURCE NOAEL studies Showing 5 of 5 studies
ValueUnitEndpointRouteSpeciesSource
3V5U97P248UNIIFDA UNII substance identifier--openFDA substances
3V5U97P248UNIIFDA UNII substance identifier--openFDA substances
3V5U97P248UNIIFDA UNII substance identifier--openFDA substances
3V5U97P248UNIIFDA UNII substance identifier--openFDA substances
=200mg/kg bw/dayNOAELoralRatToxValDB_ECHA_IUCLID

Showing 5 of 5 studies

Cosmetic Safety Profile

Same-CAS cosmetic ingredient record for cross-vertical context.

SOURCE CosIng / Ingredients DB
EU Status
permitted
Max
-
Category
antioxidant
View full cosmetic safety profile →

Frequently Asked Questions

What is the NOAEL for Propanedioic acid, 2-[(4-hydroxy-3,5-dimethoxyphenyl)methylene]-, 1,3-bis(2-ethylhexyl) ester?

Propanedioic acid, 2-[(4-hydroxy-3,5-dimethoxyphenyl)methylene]-, 1,3-bis(2-ethylhexyl) ester has 5 NOAEL studies in the database. The lowest reported value is 3V5U97P248 UNII. Source: openFDA substances.

Is Propanedioic acid, 2-[(4-hydroxy-3,5-dimethoxyphenyl)methylene]-, 1,3-bis(2-ethylhexyl) ester used in cosmetics?

Yes, Propanedioic acid, 2-[(4-hydroxy-3,5-dimethoxyphenyl)methylene]-, 1,3-bis(2-ethylhexyl) ester is also indexed as a cosmetic ingredient under the name Diethylhexyl Syringylidenemalonate. View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.

Where does the safety data for Propanedioic acid, 2-[(4-hydroxy-3,5-dimethoxyphenyl)methylene]-, 1,3-bis(2-ethylhexyl) ester come from?

Safety data is sourced from EPA ToxValDB, EPA CPDat, EPA DSSTox, CosIng / Ingredients DB. All data traces to primary regulatory sources and is updated from official government databases.

Is Propanedioic acid, 2-[(4-hydroxy-3,5-dimethoxyphenyl)methylene]-, 1,3-bis(2-ethylhexyl) ester used outside industrial chemicals?

Propanedioic acid, 2-[(4-hydroxy-3,5-dimethoxyphenyl)methylene]-, 1,3-bis(2-ethylhexyl) ester also appears in cosmetics databases.