What is the NOAEL for 3,7-Dimethylocta-2,6-dienoic acid?
3,7-Dimethylocta-2,6-dienoic acid has 5 NOAEL studies in the database. The lowest reported value is PL902IKN0A UNII. Source: openFDA substances.
NOAEL Data
Cosmetic Ingredient
3,7-Dimethylocta-2,6-dienoic acid
Also known as: Geranic acid, 2,6-Octadienoic acid, 3,7-dimethyl-, 3-02-00-01469, BRN 1763804, 3,7-Dimethyl-2,6(and 2,7)-octadienoic acid (+4 more)
CAS 459-80-3
3,7-Dimethylocta-2,6-dienoic acid (CAS 459-80-3) is a chemical substance. Key regulatory status: 4 regulatory/inventory lists, cosmetic ingredient cross-reference; source data from EPA ToxValDB, EPA CPDat, AICIS.
SOURCE
NOAEL studies
NOAEL studies
5
SOURCE
Chemical inventory jurisdictions
Regulatory lists
4
SOURCE
EU CLP Annex VI
GHS signal
Not classified
Chemical Identity
CAS, identifiers, formula, and alternate names for the matched substance record.
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DSSTox identifiers
14 fields
Name
3,7-Dimethylocta-2,6-dienoic acid
CAS Number
459-80-3
Molecular Formula
C10H16O2
InChI Key
ZHYZQXUYZJNEHD-UHFFFAOYSA-N
Monoisotopic Mass
168.11503
Synonyms
Geranic acid2,6-Octadienoic acid, 3,7-dimethyl-3-02-00-01469BRN 17638043,7-Dimethyl-2,6(and 2,7)-octadienoic acid3,7-Dimethyl-2,6-octadienoic acidEINECS 207-299-9NSC 229335UNII-PL902IKN0A
Functional Uses
Industrial and product-use categories associated with this substance.
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EPA CPDat
5 records
FragranceFlavouring and nutrient
Regulatory Lists
Inventory, screening, and regulatory list matches from public chemical databases.
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EPA CPDat
4 records
| List | Keyword | Source |
|---|---|---|
| IFRA Transparency | IFRA | IFRA |
| Europe | European Commission | Fl@vis |
| food_additive; Substances Added to Food (formerly EAFUS) (2/2019) | FDA | United States Food and Drug Administration (FDA) |
| consumer_product | P&G | Proctor & Gamble |
NOAEL Studies
Toxicology endpoints rendered from public NOAEL study rows.
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NOAEL studies
Showing 5 of 5 studies
| Value | Unit | Endpoint | Route | Species | Source |
|---|---|---|---|---|---|
| PL902IKN0A | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 0 | % | Incidence of positive responses | Dermal | Human | NTP ICE skin sensitization |
| 2700 | ug/cm2 | Induction dose per skin area | Dermal | Human | NTP ICE skin sensitization |
| =3700 | mg/kg bw | LD50 | oral | Rat | NTP ICE acute oral |
| 3 | unitless | Relative reliability score | Dermal | Human | NTP ICE skin sensitization |
Showing 5 of 5 studies
Australian Status (AICIS)
Australian industrial chemicals inventory status and applicable conditions.
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AICIS inventory
1 records
Inventory Status
listed
Cosmetic Safety Profile
Same-CAS cosmetic ingredient record for cross-vertical context.
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CosIng / Ingredients DB
EU Status
permitted
Max
-
Category
Fragrance
Food Safety Data
Same-CAS food additive, ADI, and GRAS records where available.
SOURCE
EFSA
1 records
1 food-safety record found.
View full food safety profile →Cannabis Data
Same-CAS cannabis compliance and lab records where available.
SOURCE
Cannabis regulatory / lab data
efsa substances
1 cannabis record found in efsa substances.
View full cannabis profile →Frequently Asked Questions
What regulatory lists include 3,7-Dimethylocta-2,6-dienoic acid?
3,7-Dimethylocta-2,6-dienoic acid appears on 4 regulatory/inventory lists including IFRA Transparency, Europe, food_additive; Substances Added to Food (formerly EAFUS) (2/2019), and 1 more. Source: EPA CPDat.
Is 3,7-Dimethylocta-2,6-dienoic acid used in cosmetics?
Yes, 3,7-Dimethylocta-2,6-dienoic acid is also indexed as a cosmetic ingredient under the name Geranic Acid. View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.
Where does the safety data for 3,7-Dimethylocta-2,6-dienoic acid come from?
Safety data is sourced from EPA ToxValDB, EPA CPDat, AICIS (Australian Industrial Chemicals Introduction Scheme), EPA DSSTox, CosIng / Ingredients DB, EFSA / FDA GRAS, cannabis regulatory/lab databases. All data traces to primary regulatory sources and is updated from official government databases.
Is 3,7-Dimethylocta-2,6-dienoic acid used outside industrial chemicals?
3,7-Dimethylocta-2,6-dienoic acid also appears in cosmetics, food safety, cannabis databases.