What is the NOAEL for (-)-alpha-Cedrene?
(-)-alpha-Cedrene has 7 NOAEL studies in the database. The lowest reported value is 50D4A81G8T UNII. Source: openFDA substances.
NOAEL Data
Cosmetic Ingredient
(-)-alpha-Cedrene
Also known as: (-)-Cedrene, 1H-3a,7-Methanoazulene, 2,3,4,7,8,8a-hexahydro-3,6,8,8-tetramethyl-, (3R,3aS,7S,8aS)-, 1H-3a,7-Methanoazulene, 2,3,4,7,8,8a-hexahydro-3,6,8,8-tetramethyl-, [3R-(3α,3aβ,7β,8aα)]-, Cedr-8-ene, α-Cedrene (+11 more)
CAS 469-61-4
(-)-alpha-Cedrene (CAS 469-61-4) is a chemical substance. Key regulatory status: 5 regulatory/inventory lists, cosmetic ingredient cross-reference; source data from EPA ToxValDB, EPA CPDat, AICIS.
Cross-Vertical Regulatory Divergence
(-)-alpha-Cedrene is classified GHS Danger (H226, H304, H400, H410) in the chemicals database but is allowed in EU cosmetics.
SOURCE
Cross-vertical comparison
Cosmetics: ingredients.eu_status; Chemicals: ghs_classifications.signal_word/hazard_statement_code
SOURCE
noael studies public
NOAEL studies
7
SOURCE
chemical inventory jurisdictions
Regulatory lists
5
SOURCE
eu clp annex vi
GHS signal
Not classified
Chemical Identity
CAS, identifiers, formula, and alternate names for the matched substance record.
SOURCE
DSSTox identifiers
22 fields
Name
(-)-alpha-Cedrene
CAS Number
469-61-4
DTXSID
DTXSID0047032
Molecular Formula
C15H24
InChI Key
IRAQOCYXUMOFCW-OSFYFWSMSA-N
Monoisotopic Mass
204.187801
Synonyms
(-)-Cedrene1H-3a,7-Methanoazulene, 2,3,4,7,8,8a-hexahydro-3,6,8,8-tetramethyl-, (3R,3aS,7S,8aS)-1H-3a,7-Methanoazulene, 2,3,4,7,8,8a-hexahydro-3,6,8,8-tetramethyl-, [3R-(3α,3aβ,7β,8aα)]-Cedr-8-eneα-CedreneLevo-α-cedrene[3R-(3α,3aβ,7β,8αa)]-2,3,4,7,8,8a-Hexahydro-3,6,8,8-tetramethyl-1H-3a,7-methanoazulene[3R-(3α,3aβ,7β,8aα)]-2,3,4,7,8,8a-hexahydro-3,6,8,8-tetramethyl-1H-3a,7-methanoazulene[3R-(3α,3aβ,7β,8aα)]-2,3,4,7,8,8a-Hexahydro-3,6,8,8-tetramethyl-1H-3a,7-methanoazulen[3R-(3α,3aβ,7β,8aα)]-2,3,4,7,8,8a-hexahidro-3,6,8,8-tetrametil-1H-3a,7-metanoazuleno3-05-00-01095BRN 3196861
Functional Uses
Industrial and product-use categories associated with this substance.
SOURCE
EPA CPDat
41 records
FragranceFlavouring and nutrient
Regulatory Lists
Inventory, screening, and regulatory list matches from public chemical databases.
SOURCE
EPA CPDat
5 records
| List | Keyword | Source |
|---|---|---|
| IFRA Transparency | IFRA | IFRA |
| Europe | European Commission | Fl@vis |
| Cleaning products and household care - air freshener; Europe | Danish Environmental Protection Agency | Danish EPA |
| Europe | European Chemicals Agency | European Chemicals Agency (ECHA) |
| consumer_product | P&G | Proctor & Gamble |
NOAEL Studies
Toxicology endpoints rendered from public NOAEL study rows.
SOURCE
NOAEL studies
Showing 7 of 7 studies
| Value | Unit | Endpoint | Route | Species | Source |
|---|---|---|---|---|---|
| 50D4A81G8T | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 50D4A81G8T | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 50D4A81G8T | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 50D4A81G8T | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| - | % | Incidence of positive responses | Dermal | Human | NTP_ICE_skin_sensitization |
| 3240 | ug/cm2 | Induction dose per skin area | Dermal | Human | NTP_ICE_skin_sensitization |
| 3 | unitless | Relative reliability score | Dermal | Human | NTP_ICE_skin_sensitization |
Showing 7 of 7 studies
Australian Status (AICIS)
Australian industrial chemicals inventory status and applicable conditions.
SOURCE
AICIS inventory
1 records
Inventory Status
listed
Cosmetic Safety Profile
Same-CAS cosmetic ingredient record for cross-vertical context.
SOURCE
CosIng / Ingredients DB
EU Status
permitted
Max
-
Category
Fragrance
Cannabis Data
Same-CAS cannabis compliance and lab records where available.
SOURCE
Cannabis regulatory / lab data
efsa substances
1 cannabis record found in efsa substances.
View full cannabis profile →Frequently Asked Questions
What regulatory lists include (-)-alpha-Cedrene?
(-)-alpha-Cedrene appears on 4 regulatory/inventory lists including IFRA Transparency, Europe, Cleaning products and household care - air freshener; Europe, and 1 more. Source: EPA CPDat.
Is (-)-alpha-Cedrene used in cosmetics?
Yes, (-)-alpha-Cedrene is also indexed as a cosmetic ingredient under the name Alpha-Cedrene. View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.
Where does the safety data for (-)-alpha-Cedrene come from?
Safety data is sourced from EPA ToxValDB, EPA CPDat, AICIS (Australian Industrial Chemicals Introduction Scheme), EPA DSSTox, CosIng / Ingredients DB, cannabis regulatory/lab databases. All data traces to primary regulatory sources and is updated from official government databases.
Does (-)-alpha-Cedrene have different safety status in cosmetics vs industrial chemicals?
(-)-alpha-Cedrene is classified GHS Danger (H226, H304, H400, H410) in the chemicals database but is allowed in EU cosmetics.
Is (-)-alpha-Cedrene used outside industrial chemicals?
(-)-alpha-Cedrene also appears in cosmetics, cannabis databases.