What is the NOAEL for Tangeretin?
Tangeretin has 4 NOAEL studies in the database. The lowest reported value is I4TLA1DLX6 UNII. Source: openFDA substances.
NOAEL Data
Cosmetic Ingredient
Tangeretin
Also known as: 5-18-05-00491, 4H-1-Benzopyran-4-one, 5,6,7,8-tetramethoxy-2-(p-methoxyphenyl)-, BRN 0351695, EINECS 207-570-1, 2-(4-Methoxyphenyl)-5,6,7,8-tetramethoxy-4H-1-benzopyran-4-one (+8 more)
CAS 481-53-8
Tangeretin (CAS 481-53-8) is a chemical substance. Key regulatory status: cosmetic ingredient cross-reference; source data from EPA ToxValDB, EPA CPDat.
Cross-Vertical Regulatory Divergence
Tangeretin is classified GHS Danger (H300) in the chemicals database but is allowed in EU cosmetics.
SOURCE
Cross-vertical comparison
Cosmetics: ingredients.eu_status; Chemicals: ghs_classifications.signal_word/hazard_statement_code
SOURCE
noael studies public
NOAEL studies
4
SOURCE
chemical inventory jurisdictions
Regulatory lists
0
SOURCE
eu clp annex vi
GHS signal
Not classified
Chemical Identity
CAS, identifiers, formula, and alternate names for the matched substance record.
SOURCE
DSSTox identifiers
19 fields
Name
Tangeretin
CAS Number
481-53-8
DTXSID
DTXSID30197417
Molecular Formula
C20H20O7
InChI Key
ULSUXBXHSYSGDT-UHFFFAOYSA-N
Monoisotopic Mass
372.120903
Synonyms
5-18-05-004914H-1-Benzopyran-4-one, 5,6,7,8-tetramethoxy-2-(p-methoxyphenyl)-BRN 0351695EINECS 207-570-12-(4-Methoxyphenyl)-5,6,7,8-tetramethoxy-4H-1-benzopyran-4-oneNSC 53909Pentamethoxyflavone4',5,6,7,8-PentamethoxyflavonePonkanetinUNII-I4TLA1DLX65,6,7,8,4'-Pentamethoxyflavone5,6,7,8-tetramethoxy-2-(4-methoxyphenyl)-4H-1-benzopyran-4-one
Functional Uses
Industrial and product-use categories associated with this substance.
SOURCE
EPA CPDat
2 records
AntioxidantSoftener and conditioner
NOAEL Studies
Toxicology endpoints rendered from public NOAEL study rows.
SOURCE
NOAEL studies
Showing 4 of 4 studies
| Value | Unit | Endpoint | Route | Species | Source |
|---|---|---|---|---|---|
| I4TLA1DLX6 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| I4TLA1DLX6 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| I4TLA1DLX6 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| I4TLA1DLX6 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
Showing 4 of 4 studies
Cosmetic Safety Profile
Same-CAS cosmetic ingredient record for cross-vertical context.
SOURCE
CosIng / Ingredients DB
EU Status
permitted
Max
-
Category
Antioxidant
Pharmaceutical Data
Same-CAS pharmaceutical records from drug and bioactivity sources.
SOURCE
EMBL-EBI ChEMBL
TANGERETIN
ChEMBL Phase
Not listed
Adverse Events
0
Bioactivity
8
Food Safety Data
Same-CAS food additive, ADI, and GRAS records where available.
SOURCE
EFSA / FDA GRAS
1 records
1 food-safety record found.
View full food safety profile →Cannabis Data
Same-CAS cannabis compliance and lab records where available.
SOURCE
Cannabis regulatory / lab data
efsa substances
1 cannabis record found in efsa substances.
View full cannabis profile →Frequently Asked Questions
Is Tangeretin used in cosmetics?
Yes, Tangeretin is also indexed as a cosmetic ingredient under the name Tangeritin. View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.
Where does the safety data for Tangeretin come from?
Safety data is sourced from EPA ToxValDB, EPA CPDat, EPA DSSTox, CosIng / Ingredients DB, ChEMBL / DailyMed, EFSA / FDA GRAS, cannabis regulatory/lab databases. All data traces to primary regulatory sources and is updated from official government databases.
Does Tangeretin have different safety status in cosmetics vs industrial chemicals?
Tangeretin is classified GHS Danger (H300) in the chemicals database but is allowed in EU cosmetics.
Is Tangeretin used outside industrial chemicals?
Tangeretin also appears in cosmetics, pharmaceutical, food safety, cannabis databases.