What is the NOAEL for (-)-Epicatechin?
(-)-Epicatechin has 4 NOAEL studies in the database. The lowest reported value is 34PHS7TU43 UNII. Source: openFDA substances.
NOAEL Data
Cosmetic Ingredient
(-)-Epicatechin
Also known as: EINECS 207-710-1, UNII-34PHS7TU43, (2R,3R)-2-(3,4-dihydroxyphenyl)-3,4-dihydro-2H-1-benzopyran-3,5,7-triol, 3,3',4',5,7-Pentahydroxyflavane, Epigallocatechin (+2 more)
CAS 490-46-0
(-)-Epicatechin (CAS 490-46-0) is a chemical substance. Key regulatory status: 3 regulatory/inventory lists, cosmetic ingredient cross-reference; source data from EPA ToxValDB, EPA CPDat.
SOURCE
NOAEL studies
NOAEL studies
4
SOURCE
Chemical inventory jurisdictions
Regulatory lists
3
SOURCE
EU CLP Annex VI
GHS signal
Not classified
Chemical Identity
CAS, identifiers, formula, and alternate names for the matched substance record.
SOURCE
DSSTox identifiers
13 fields
Name
(-)-Epicatechin
CAS Number
490-46-0
DTXSID
DTXSID4045133
Molecular Formula
C15H14O6
InChI Key
PFTAWBLQPZVEMU-UKRRQHHQSA-N
Monoisotopic Mass
290.079038
Synonyms
EINECS 207-710-1UNII-34PHS7TU43(2R,3R)-2-(3,4-dihydroxyphenyl)-3,4-dihydro-2H-1-benzopyran-3,5,7-triol3,3',4',5,7-PentahydroxyflavaneEpigallocatechinL(-)-Epicatechinalpha-Catechin
Regulatory Lists
Inventory, screening, and regulatory list matches from public chemical databases.
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EPA CPDat
3 records
| List | Keyword | Source |
|---|---|---|
| Canada; pharmaceutical | DrugBank | DrugBank |
| Canada; pharmaceutical | DrugBank | DrugBank |
| Canada; pharmaceutical | DrugBank | DrugBank |
NOAEL Studies
Toxicology endpoints rendered from public NOAEL study rows.
SOURCE
NOAEL studies
Showing 4 of 4 studies
| Value | Unit | Endpoint | Route | Species | Source |
|---|---|---|---|---|---|
| 34PHS7TU43 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 34PHS7TU43 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 34PHS7TU43 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 34PHS7TU43 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
Showing 4 of 4 studies
Cosmetic Safety Profile
Same-CAS cosmetic ingredient record for cross-vertical context.
SOURCE
CosIng / Ingredients DB
EU Status
permitted
Max
0.5–5% (as component of green tea extract)
Category
antioxidant
Pharmaceutical Data
Same-CAS pharmaceutical records from drug and bioactivity sources.
SOURCE
ChEMBL / DailyMed
(-)-EPICATECHIN
ChEMBL Phase
2
Adverse Events
0
Bioactivity
9
Food Safety Data
Same-CAS food additive, ADI, and GRAS records where available.
SOURCE
EFSA
1 records
1 food-safety record found.
View full food safety profile →Cannabis Data
Same-CAS cannabis compliance and lab records where available.
SOURCE
Cannabis regulatory / lab data
efsa substances
1 cannabis record found in efsa substances.
View full cannabis profile →Frequently Asked Questions
What regulatory lists include (-)-Epicatechin?
(-)-Epicatechin appears on 1 regulatory/inventory list including Canada; pharmaceutical. Source: EPA CPDat.
Is (-)-Epicatechin used in cosmetics?
Yes, (-)-Epicatechin is also indexed as a cosmetic ingredient under the name Epicatechin. View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.
Where does the safety data for (-)-Epicatechin come from?
Safety data is sourced from EPA ToxValDB, EPA CPDat, EPA DSSTox, CosIng / Ingredients DB, ChEMBL / DailyMed, EFSA / FDA GRAS, cannabis regulatory/lab databases. All data traces to primary regulatory sources and is updated from official government databases.
Is (-)-Epicatechin used outside industrial chemicals?
(-)-Epicatechin also appears in cosmetics, pharmaceutical, food safety, cannabis databases.