NOAEL Data Cosmetic Ingredient

Beta-Thujaplicin

Also known as: 4-08-00-00488, BRN 2045206, EINECS 207-880-7, Hinokitol, beta-Isopropyltropolon (+5 more)

CAS 499-44-5

Beta-Thujaplicin (CAS 499-44-5) is a chemical substance. Key regulatory status: 2 regulatory/inventory lists, cosmetic ingredient cross-reference; source data from EPA ToxValDB, EPA CPDat, AICIS.

View cosmetic safety profile for Hinokitiol →

SOURCE noael studies public
NOAEL studies
4
SOURCE chemical inventory jurisdictions
Regulatory lists
2
SOURCE eu clp annex vi
GHS signal
Not classified

Chemical Identity

CAS, identifiers, formula, and alternate names for the matched substance record.

SOURCE DSSTox identifiers 16 fields
Name
Beta-Thujaplicin
CAS Number
499-44-5
DTXSID
DTXSID6043911
Molecular Formula
C10H12O2
InChI Key
FUWUEFKEXZQKKA-UHFFFAOYSA-N
Monoisotopic Mass
164.08373
Synonyms
4-08-00-00488BRN 2045206EINECS 207-880-7Hinokitolbeta-IsopropyltropolonTHUJAPLICIN, BETAbeta-ThujaplicineTropolone, 4-isopropyl-UNII-U5335D6EBIHyka 1

Functional Uses

Industrial and product-use categories associated with this substance.

SOURCE EPA CPDat 7 records
Anti-static agentSoftener and conditionerFragrance

Regulatory Lists

Inventory, screening, and regulatory list matches from public chemical databases.

SOURCE EPA CPDat 2 records
ListKeywordSource
IFRA TransparencyIFRAIFRA
active_ingredient; Europe; PesticidesCommission of the European CommunitiesCPCat

NOAEL Studies

Toxicology endpoints rendered from public NOAEL study rows.

SOURCE NOAEL studies Showing 4 of 4 studies
ValueUnitEndpointRouteSpeciesSource
U5335D6EBIUNIIFDA UNII substance identifier--openFDA substances
U5335D6EBIUNIIFDA UNII substance identifier--openFDA substances
U5335D6EBIUNIIFDA UNII substance identifier--openFDA substances
U5335D6EBIUNIIFDA UNII substance identifier--openFDA substances

Showing 4 of 4 studies

Australian Status (AICIS)

Australian industrial chemicals inventory status and applicable conditions.

SOURCE AICIS inventory 1 records
Inventory Status
listed

Cosmetic Safety Profile

Same-CAS cosmetic ingredient record for cross-vertical context.

SOURCE CosIng / Ingredients DB
EU Status
permitted
Max
-
Category
Other
View full cosmetic safety profile →

Pharmaceutical Data

Same-CAS pharmaceutical records from drug and bioactivity sources.

SOURCE EMBL-EBI ChEMBL HINOKITIOL
ChEMBL Phase
Not listed
Adverse Events
0
Bioactivity
7
View full pharmaceutical profile →

Frequently Asked Questions

What is the NOAEL for Beta-Thujaplicin?

Beta-Thujaplicin has 4 NOAEL studies in the database. The lowest reported value is U5335D6EBI UNII. Source: openFDA substances.

What regulatory lists include Beta-Thujaplicin?

Beta-Thujaplicin appears on 2 regulatory/inventory lists including IFRA Transparency, active_ingredient; Europe; Pesticides. Source: EPA CPDat.

Is Beta-Thujaplicin used in cosmetics?

Yes, Beta-Thujaplicin is also indexed as a cosmetic ingredient under the name Hinokitiol. View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.

Where does the safety data for Beta-Thujaplicin come from?

Safety data is sourced from EPA ToxValDB, EPA CPDat, AICIS (Australian Industrial Chemicals Introduction Scheme), EPA DSSTox, CosIng / Ingredients DB, ChEMBL / DailyMed. All data traces to primary regulatory sources and is updated from official government databases.

Is Beta-Thujaplicin used outside industrial chemicals?

Beta-Thujaplicin also appears in cosmetics, pharmaceutical databases.