What is the NOAEL for Benzoxazole, 2,2'-(1,4-naphthalenediyl)bis-?
Benzoxazole, 2,2'-(1,4-naphthalenediyl)bis- has 4 NOAEL studies in the database. The lowest reported value is Z945S0K4ZW UNII. Source: openFDA substances.
NOAEL Data
REACH Registered
Cosmetic Ingredient
Benzoxazole, 2,2'-(1,4-naphthalenediyl)bis-
Also known as: EINECS 225-803-5, UNII-Z945S0K4ZW
CAS 5089-22-5
Benzoxazole, 2,2'-(1,4-naphthalenediyl)bis- (CAS 5089-22-5) is a chemical substance. Key regulatory status: REACH registered, cosmetic ingredient cross-reference; source data from EPA ToxValDB, EPA CPDat, AICIS, ECHA REACH.
View cosmetic safety profile for Fluorescent Brightening Agent 367 →
Cross-Vertical Regulatory Divergence
Benzoxazole, 2,2'-(1,4-naphthalenediyl)bis- is prohibited in EU cosmetics but has active industrial GHS classifications (H413).
SOURCE
Cross-vertical comparison
Cosmetics: ingredients.eu_status; Chemicals: ghs_classifications.signal_word/hazard_statement_code
SOURCE
noael studies public
NOAEL studies
4
SOURCE
chemical inventory jurisdictions
Regulatory lists
0
SOURCE
eu clp annex vi
GHS signal
Not classified
Chemical Identity
CAS, identifiers, formula, and alternate names for the matched substance record.
SOURCE
DSSTox identifiers
8 fields
Name
Benzoxazole, 2,2'-(1,4-naphthalenediyl)bis-
CAS Number
5089-22-5
DTXSID
DTXSID6063698
Molecular Formula
C24H14N2O2
InChI Key
WFYSPVCBIJCZPX-UHFFFAOYSA-N
Monoisotopic Mass
362.105528
Synonyms
EINECS 225-803-5UNII-Z945S0K4ZW
Functional Uses
Industrial and product-use categories associated with this substance.
SOURCE
EPA CPDat
10 records
Brightener
NOAEL Studies
Toxicology endpoints rendered from public NOAEL study rows.
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NOAEL studies
Showing 4 of 4 studies
| Value | Unit | Endpoint | Route | Species | Source |
|---|---|---|---|---|---|
| Z945S0K4ZW | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| Z945S0K4ZW | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| Z945S0K4ZW | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| Z945S0K4ZW | UNII | FDA UNII substance identifier | - | - | openFDA substances |
Showing 4 of 4 studies
REACH Registration
Registration status from the ECHA REACH registered substances database.
SOURCE
ECHA (EU)
1 records
| Status | Name | EC Number | Link |
|---|---|---|---|
| Registered | 2,2'-(naphthalene-1,4-diyl)bis(benzoxazole) | 225-803-5 | ECHA overview → |
Australian Status (AICIS)
Australian industrial chemicals inventory status and applicable conditions.
SOURCE
AICIS inventory
1 records
Inventory Status
listed
Cosmetic Safety Profile
Same-CAS cosmetic ingredient record for cross-vertical context.
SOURCE
CosIng / Ingredients DB
EU Status
prohibited
Max
-
Category
Synthetic Polymers
Frequently Asked Questions
Is Benzoxazole, 2,2'-(1,4-naphthalenediyl)bis- used in cosmetics?
Yes, Benzoxazole, 2,2'-(1,4-naphthalenediyl)bis- is also indexed as a cosmetic ingredient under the name Fluorescent Brightening Agent 367. View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.
Where does the safety data for Benzoxazole, 2,2'-(1,4-naphthalenediyl)bis- come from?
Safety data is sourced from EPA ToxValDB, EPA CPDat, AICIS (Australian Industrial Chemicals Introduction Scheme), EPA DSSTox, ECHA REACH, CosIng / Ingredients DB. All data traces to primary regulatory sources and is updated from official government databases.
Does Benzoxazole, 2,2'-(1,4-naphthalenediyl)bis- have different safety status in cosmetics vs industrial chemicals?
Benzoxazole, 2,2'-(1,4-naphthalenediyl)bis- is prohibited in EU cosmetics but has active industrial GHS classifications (H413).
Is Benzoxazole, 2,2'-(1,4-naphthalenediyl)bis- used outside industrial chemicals?
Benzoxazole, 2,2'-(1,4-naphthalenediyl)bis- also appears in cosmetics databases.