What is the NOAEL for 3,7-Dimethyloct-6-enenitrile?
3,7-Dimethyloct-6-enenitrile has 9 NOAEL studies in the database. The lowest reported value is 17.6 mg/m3 via inhalation in Human. Source: ToxValDB_GESTIS_DNEL.
NOAEL Data
REACH Registered
Cosmetic Ingredient
3,7-Dimethyloct-6-enenitrile
Also known as: 6-Octenenitrile, 3,7-dimethyl-, Citronellonitrile, Citronellyl nitrile, 3,7-Dimethyl-6-octene-1-nitrile, EINECS 257-288-8
CAS 51566-62-2
3,7-Dimethyloct-6-enenitrile (CAS 51566-62-2) is a chemical substance. Key regulatory status: REACH registered, 1 regulatory/inventory list, cosmetic ingredient cross-reference; source data from EPA ToxValDB, EPA CPDat, AICIS, ECHA REACH.
SOURCE
noael studies public
NOAEL studies
9
SOURCE
chemical inventory jurisdictions
Regulatory lists
1
SOURCE
eu clp annex vi
GHS signal
Not classified
Chemical Identity
CAS, identifiers, formula, and alternate names for the matched substance record.
SOURCE
DSSTox identifiers
11 fields
Name
3,7-Dimethyloct-6-enenitrile
CAS Number
51566-62-2
DTXSID
DTXSID7052155
Molecular Formula
C10H17N
InChI Key
MTDAKBBUYMYKAR-UHFFFAOYSA-N
Monoisotopic Mass
151.1361
Synonyms
6-Octenenitrile, 3,7-dimethyl-CitronellonitrileCitronellyl nitrile3,7-Dimethyl-6-octene-1-nitrileEINECS 257-288-8
Functional Uses
Industrial and product-use categories associated with this substance.
SOURCE
EPA CPDat
60 records
Fragrance
Regulatory Lists
Inventory, screening, and regulatory list matches from public chemical databases.
SOURCE
EPA CPDat
1 records
| List | Keyword | Source |
|---|---|---|
| IFRA Transparency | IFRA | IFRA |
NOAEL Studies
Toxicology endpoints rendered from public NOAEL study rows.
SOURCE
NOAEL studies
Showing 9 of 9 studies
| Value | Unit | Endpoint | Route | Species | Source |
|---|---|---|---|---|---|
| =17.6 | mg/m3 | DNEL systemic | inhalation | Human | ToxValDB_GESTIS_DNEL |
| GP9AT16H16 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| GP9AT16H16 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| GP9AT16H16 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| GP9AT16H16 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| - | % | Incidence of positive responses | Dermal | Human | NTP_ICE_skin_sensitization |
| 4050 | ug/cm2 | Induction dose per skin area | Dermal | Human | NTP_ICE_skin_sensitization |
| =5300 | mg/kg bw | LD50 | oral | Rat | NTP_ICE_acute_oral |
| 3 | unitless | Relative reliability score | Dermal | Human | NTP_ICE_skin_sensitization |
Showing 9 of 9 studies
REACH Registration
Registration status from the ECHA REACH registered substances database.
SOURCE
ECHA (EU)
1 records
| Status | Name | EC Number | Link |
|---|---|---|---|
| Registered | 3,7-dimethyloct-6-enenitrile | 257-288-8 | ECHA overview → |
Australian Status (AICIS)
Australian industrial chemicals inventory status and applicable conditions.
SOURCE
AICIS inventory
1 records
Inventory Status
listed
Cosmetic Safety Profile
Same-CAS cosmetic ingredient record for cross-vertical context.
SOURCE
CosIng / Ingredients DB
EU Status
permitted
Max
-
Category
Fragrance
Frequently Asked Questions
What regulatory lists include 3,7-Dimethyloct-6-enenitrile?
3,7-Dimethyloct-6-enenitrile appears on 1 regulatory/inventory list including IFRA Transparency. Source: EPA CPDat.
Is 3,7-Dimethyloct-6-enenitrile used in cosmetics?
Yes, 3,7-Dimethyloct-6-enenitrile is also indexed as a cosmetic ingredient under the name Citronellyl Nitrile. View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.
Where does the safety data for 3,7-Dimethyloct-6-enenitrile come from?
Safety data is sourced from EPA ToxValDB, EPA CPDat, AICIS (Australian Industrial Chemicals Introduction Scheme), EPA DSSTox, ECHA REACH, CosIng / Ingredients DB. All data traces to primary regulatory sources and is updated from official government databases.
Is 3,7-Dimethyloct-6-enenitrile used outside industrial chemicals?
3,7-Dimethyloct-6-enenitrile also appears in cosmetics databases.