What is the NOAEL for 3-Methyl-2-butenyl benzoate?
3-Methyl-2-butenyl benzoate has 8 NOAEL studies in the database. The lowest reported value is O577ZIE86G UNII. Source: openFDA substances.
NOAEL Data
Cosmetic Ingredient
3-Methyl-2-butenyl benzoate
Also known as: Benzoic acid, 3-methyl-2-butenyl ester, BRN 2046710, EINECS 225-998-7, 3-Methylbut-2-enyl benzoate, UNII-O577ZIE86G
CAS 5205-11-8
3-Methyl-2-butenyl benzoate (CAS 5205-11-8) is a chemical substance. Key regulatory status: 4 regulatory/inventory lists, cosmetic ingredient cross-reference; source data from EPA ToxValDB, EPA CPDat, AICIS.
SOURCE
noael studies public
NOAEL studies
8
SOURCE
chemical inventory jurisdictions
Regulatory lists
4
SOURCE
eu clp annex vi
GHS signal
Not classified
Chemical Identity
CAS, identifiers, formula, and alternate names for the matched substance record.
SOURCE
DSSTox identifiers
11 fields
Name
3-Methyl-2-butenyl benzoate
CAS Number
5205-11-8
DTXSID
DTXSID8047131
Molecular Formula
C12H14O2
InChI Key
INVWRXWYYVMFQC-UHFFFAOYSA-N
Monoisotopic Mass
190.09938
Synonyms
Benzoic acid, 3-methyl-2-butenyl esterBRN 2046710EINECS 225-998-73-Methylbut-2-enyl benzoateUNII-O577ZIE86G
Functional Uses
Industrial and product-use categories associated with this substance.
SOURCE
EPA CPDat
5 records
FragranceFlavouring and nutrient
Regulatory Lists
Inventory, screening, and regulatory list matches from public chemical databases.
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EPA CPDat
4 records
| List | Keyword | Source |
|---|---|---|
| IFRA Transparency | IFRA | IFRA |
| consumer_product | P&G | Proctor & Gamble |
| Europe | European Commission | Fl@vis |
| food_additive; Substances Added to Food (formerly EAFUS) (2/2019) | FDA | United States Food and Drug Administration (FDA) |
NOAEL Studies
Toxicology endpoints rendered from public NOAEL study rows.
SOURCE
NOAEL studies
Showing 8 of 8 studies
| Value | Unit | Endpoint | Route | Species | Source |
|---|---|---|---|---|---|
| O577ZIE86G | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| O577ZIE86G | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| O577ZIE86G | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| O577ZIE86G | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| - | % | Incidence of positive responses | Dermal | Human | NTP_ICE_skin_sensitization |
| 13500 | ug/cm2 | Induction dose per skin area | Dermal | Human | NTP_ICE_skin_sensitization |
| =4700 | mg/kg bw | LD50 | oral | Rat | NTP_ICE_acute_oral |
| 3 | unitless | Relative reliability score | Dermal | Human | NTP_ICE_skin_sensitization |
Showing 8 of 8 studies
Australian Status (AICIS)
Australian industrial chemicals inventory status and applicable conditions.
SOURCE
AICIS inventory
1 records
Inventory Status
listed
Cosmetic Safety Profile
Same-CAS cosmetic ingredient record for cross-vertical context.
SOURCE
CosIng / Ingredients DB
EU Status
permitted
Max
0.24%
Category
Fragrance
Pharmaceutical Data
Same-CAS pharmaceutical records from drug and bioactivity sources.
SOURCE
EMBL-EBI ChEMBL
BENZOIC ACID 3-METHYL-2-BUTENYL ESTER
ChEMBL Phase
Not listed
Adverse Events
0
Bioactivity
0
Food Safety Data
Same-CAS food additive, ADI, and GRAS records where available.
SOURCE
EFSA / FDA GRAS
1 records
ADI: No safety concern at current levels of intake when used as a flavouring agent mg/kg bw
View full food safety profile →Cannabis Data
Same-CAS cannabis compliance and lab records where available.
SOURCE
Cannabis regulatory / lab data
efsa substances
1 cannabis record found in efsa substances.
View full cannabis profile →Frequently Asked Questions
What regulatory lists include 3-Methyl-2-butenyl benzoate?
3-Methyl-2-butenyl benzoate appears on 4 regulatory/inventory lists including IFRA Transparency, consumer_product, Europe, and 1 more. Source: EPA CPDat.
Is 3-Methyl-2-butenyl benzoate used in cosmetics?
Yes, 3-Methyl-2-butenyl benzoate is also indexed as a cosmetic ingredient under the name Prenyl Benzoate. View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.
Where does the safety data for 3-Methyl-2-butenyl benzoate come from?
Safety data is sourced from EPA ToxValDB, EPA CPDat, AICIS (Australian Industrial Chemicals Introduction Scheme), EPA DSSTox, CosIng / Ingredients DB, ChEMBL / DailyMed, EFSA / FDA GRAS, cannabis regulatory/lab databases. All data traces to primary regulatory sources and is updated from official government databases.
Is 3-Methyl-2-butenyl benzoate used outside industrial chemicals?
3-Methyl-2-butenyl benzoate also appears in cosmetics, pharmaceutical, food safety, cannabis databases.