NOAEL Data REACH Registered Cosmetic Ingredient

(3S)-1,3,4-Trihydroxy-2-butanone

Also known as: L-Erythrulose, 2-​Butanone, 1,​3,​4-​trihydroxy-​, (3S)​-, 2-Butanone, 1,3,4-trihydroxy-, (S)-, L-glycero-Tetrulose, (3S)-1,3,4-Trihydroxybutan-2-one (+1 more)

CAS 533-50-6

(3S)-1,3,4-Trihydroxy-2-butanone (CAS 533-50-6) is a chemical substance. Key regulatory status: REACH registered, cosmetic ingredient cross-reference; source data from EPA ToxValDB, AICIS, ECHA REACH.

View cosmetic safety profile for Erythrulose →

SOURCE NOAEL studies
NOAEL studies
4
SOURCE Chemical inventory jurisdictions
Regulatory lists
0
SOURCE EU CLP Annex VI
GHS signal
Not classified

Chemical Identity

CAS, identifiers, formula, and alternate names for the matched substance record.

SOURCE DSSTox identifiers 12 fields
Name
(3S)-1,3,4-Trihydroxy-2-butanone
CAS Number
533-50-6
DTXSID
DTXSID801019042
Molecular Formula
C4H8O4
InChI Key
UQPHVQVXLPRNCX-VKHMYHEASA-N
Monoisotopic Mass
120.042259
Synonyms
L-Erythrulose2-​Butanone, 1,​3,​4-​trihydroxy-​, (3S)​-2-Butanone, 1,3,4-trihydroxy-, (S)-L-glycero-Tetrulose(3S)-1,3,4-Trihydroxybutan-2-oneEC No.: 610-990-1

NOAEL Studies

Toxicology endpoints rendered from public NOAEL study rows.

SOURCE NOAEL studies Showing 4 of 4 studies
ValueUnitEndpointRouteSpeciesSource
WKK1W5B83OUNIIFDA UNII substance identifier--openFDA substances
WKK1W5B83OUNIIFDA UNII substance identifier--openFDA substances
WKK1W5B83OUNIIFDA UNII substance identifier--openFDA substances
WKK1W5B83OUNIIFDA UNII substance identifier--openFDA substances

Showing 4 of 4 studies

REACH Registration

Registration status from the ECHA REACH registered substances database.

SOURCE ECHA 1 records
StatusNameEC NumberLink
Registered(3S)-1,3,4-Trihydroxy-2-butanone443-800-9ECHA overview →

Australian Status (AICIS)

Australian industrial chemicals inventory status and applicable conditions.

SOURCE AICIS inventory 1 records
Inventory Status
listed_with_terms
Conditions
Specific information requirements: Obligations to provide information apply. You must tell us within 28 days if the circumstances of your importation or manufacture (introduction) are different to those in our assessment.

Cosmetic Safety Profile

Same-CAS cosmetic ingredient record for cross-vertical context.

SOURCE CosIng / Ingredients DB
EU Status
permitted
Max
-
Category
Humectants
View full cosmetic safety profile →

Food Safety Data

Same-CAS food additive, ADI, and GRAS records where available.

SOURCE EFSA 1 records

1 food-safety record found.

View full food safety profile →

Frequently Asked Questions

What is the NOAEL for (3S)-1,3,4-Trihydroxy-2-butanone?

(3S)-1,3,4-Trihydroxy-2-butanone has 4 NOAEL studies in the database. The lowest reported value is WKK1W5B83O UNII. Source: openFDA substances.

Is (3S)-1,3,4-Trihydroxy-2-butanone used in cosmetics?

Yes, (3S)-1,3,4-Trihydroxy-2-butanone is also indexed as a cosmetic ingredient under the name Erythrulose. View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.

Where does the safety data for (3S)-1,3,4-Trihydroxy-2-butanone come from?

Safety data is sourced from EPA ToxValDB, AICIS (Australian Industrial Chemicals Introduction Scheme), EPA DSSTox, ECHA REACH, CosIng / Ingredients DB, EFSA / FDA GRAS. All data traces to primary regulatory sources and is updated from official government databases.

Is (3S)-1,3,4-Trihydroxy-2-butanone used outside industrial chemicals?

(3S)-1,3,4-Trihydroxy-2-butanone also appears in cosmetics, food safety databases.