NOAEL Data Cosmetic Ingredient

Pterostilbene

Also known as: 3,5-Dimethoxy-4'-hydroxy-trans-stilbene, 4-Stilbenol, 3',5'-dimethoxy-, (E)-, 4-((E)-2-(3,5-Dimethoxyphenyl)ethenyl)phenol, (E)-1-hydroxy-4-(3,5-dimethoxy)styrylbenzene, (E)-3',5'-dimethoxy-4-stilbenol (+6 more)

CAS 537-42-8

Pterostilbene (CAS 537-42-8) is a chemical substance. Key regulatory status: cosmetic ingredient cross-reference; source data from EPA ToxValDB, EPA CPDat.

View cosmetic safety profile for Pterostilbene →

SOURCE noael studies public
NOAEL studies
4
SOURCE chemical inventory jurisdictions
Regulatory lists
0
SOURCE eu clp annex vi
GHS signal
Not classified

Chemical Identity

CAS, identifiers, formula, and alternate names for the matched substance record.

SOURCE DSSTox identifiers 17 fields
Name
Pterostilbene
CAS Number
537-42-8
DTXSID
DTXSID9041106
Molecular Formula
C16H16O3
InChI Key
VLEUZFDZJKSGMX-ONEGZZNKSA-N
Monoisotopic Mass
256.109944
Synonyms
3,5-Dimethoxy-4'-hydroxy-trans-stilbene4-Stilbenol, 3',5'-dimethoxy-, (E)-4-((E)-2-(3,5-Dimethoxyphenyl)ethenyl)phenol(E)-1-hydroxy-4-(3,5-dimethoxy)styrylbenzene(E)-3',5'-dimethoxy-4-stilbenol(E)-4'-hydroxy-3,5-dimethoxystilbene3',5'-dimethoxy-4-stilbenol3',5'-dimethoxy-resveratrol4-(2-(3,5-Dimethoxyphenyl)ethenyl)phenol4-[(E)-2-(3,5-dimethoxyphenyl)vinyl]phenoltrans-pterostilbene

Functional Uses

Industrial and product-use categories associated with this substance.

SOURCE EPA CPDat 2 records
AntioxidantSoftener and conditioner

NOAEL Studies

Toxicology endpoints rendered from public NOAEL study rows.

SOURCE NOAEL studies Showing 4 of 4 studies
ValueUnitEndpointRouteSpeciesSource
26R60S6A5IUNIIFDA UNII substance identifier--openFDA substances
26R60S6A5IUNIIFDA UNII substance identifier--openFDA substances
26R60S6A5IUNIIFDA UNII substance identifier--openFDA substances
26R60S6A5IUNIIFDA UNII substance identifier--openFDA substances

Showing 4 of 4 studies

Cosmetic Safety Profile

Same-CAS cosmetic ingredient record for cross-vertical context.

SOURCE CosIng / Ingredients DB
EU Status
permitted
Max
-
Category
Antioxidant
View full cosmetic safety profile →

Pharmaceutical Data

Same-CAS pharmaceutical records from drug and bioactivity sources.

SOURCE EMBL-EBI ChEMBL PTEROSTILBENE
ChEMBL Phase
2
Adverse Events
0
Bioactivity
10
View full pharmaceutical profile →

Frequently Asked Questions

What is the NOAEL for Pterostilbene?

Pterostilbene has 4 NOAEL studies in the database. The lowest reported value is 26R60S6A5I UNII. Source: openFDA substances.

Is Pterostilbene used in cosmetics?

Yes, Pterostilbene is also indexed as a cosmetic ingredient under the name Pterostilbene. View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.

Where does the safety data for Pterostilbene come from?

Safety data is sourced from EPA ToxValDB, EPA CPDat, EPA DSSTox, CosIng / Ingredients DB, ChEMBL / DailyMed. All data traces to primary regulatory sources and is updated from official government databases.

Does Pterostilbene have different safety status in cosmetics vs industrial chemicals?

Pterostilbene is classified GHS Danger (H318, H411) in the chemicals database but is allowed in EU cosmetics.

Is Pterostilbene used outside industrial chemicals?

Pterostilbene also appears in cosmetics, pharmaceutical databases.