NOAEL Data Cosmetic Ingredient

Hordenine

Also known as: EINECS 208-710-4, UNII-K3489CA082, 4-[2-(Dimethylamino)ethyl]phenol, N,N-Dimethyl-2-(4-hydroxyphenyl)ethylamine, N,N-Dimethyl-4-hydroxy-beta-phenethylamine (+2 more)

CAS 539-15-1

Hordenine (CAS 539-15-1) is a chemical substance. Key regulatory status: cosmetic ingredient cross-reference; source data from EPA ToxValDB, EPA CPDat.

View cosmetic safety profile for Hordenine →

SOURCE noael studies public
NOAEL studies
4
SOURCE chemical inventory jurisdictions
Regulatory lists
0
SOURCE eu clp annex vi
GHS signal
Not classified

Chemical Identity

CAS, identifiers, formula, and alternate names for the matched substance record.

SOURCE DSSTox identifiers 13 fields
Name
Hordenine
CAS Number
539-15-1
DTXSID
DTXSID2046096
Molecular Formula
C10H15NO
InChI Key
KUBCEEMXQZUPDQ-UHFFFAOYSA-N
Monoisotopic Mass
165.115364
Synonyms
EINECS 208-710-4UNII-K3489CA0824-[2-(Dimethylamino)ethyl]phenolN,N-Dimethyl-2-(4-hydroxyphenyl)ethylamineN,N-Dimethyl-4-hydroxy-beta-phenethylamineN,N-Dimethyltyraminep-(2-Dimethylaminoethyl)phenol

Functional Uses

Industrial and product-use categories associated with this substance.

SOURCE EPA CPDat 1 records
Humectant

NOAEL Studies

Toxicology endpoints rendered from public NOAEL study rows.

SOURCE NOAEL studies Showing 4 of 4 studies
ValueUnitEndpointRouteSpeciesSource
K3489CA082UNIIFDA UNII substance identifier--openFDA substances
K3489CA082UNIIFDA UNII substance identifier--openFDA substances
K3489CA082UNIIFDA UNII substance identifier--openFDA substances
K3489CA082UNIIFDA UNII substance identifier--openFDA substances

Showing 4 of 4 studies

Cosmetic Safety Profile

Same-CAS cosmetic ingredient record for cross-vertical context.

SOURCE CosIng / Ingredients DB
EU Status
permitted
Max
-
Category
Skin Conditioning
View full cosmetic safety profile →

Pharmaceutical Data

Same-CAS pharmaceutical records from drug and bioactivity sources.

SOURCE EMBL-EBI ChEMBL HORDENINE
ChEMBL Phase
Not listed
Adverse Events
0
Bioactivity
3
View full pharmaceutical profile →

Food Safety Data

Same-CAS food additive, ADI, and GRAS records where available.

SOURCE EFSA / FDA GRAS 1 records

1 food-safety record found.

View full food safety profile →

Frequently Asked Questions

What is the NOAEL for Hordenine?

Hordenine has 4 NOAEL studies in the database. The lowest reported value is K3489CA082 UNII. Source: openFDA substances.

Is Hordenine used in cosmetics?

Yes, Hordenine is also indexed as a cosmetic ingredient under the name Hordenine. View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.

Where does the safety data for Hordenine come from?

Safety data is sourced from EPA ToxValDB, EPA CPDat, EPA DSSTox, CosIng / Ingredients DB, ChEMBL / DailyMed, EFSA / FDA GRAS. All data traces to primary regulatory sources and is updated from official government databases.

Is Hordenine used outside industrial chemicals?

Hordenine also appears in cosmetics, pharmaceutical, food safety databases.