NOAEL Data REACH Registered Cosmetic Ingredient

3-Methylcyclopentadecan-1-one

Also known as: Cyclopentadecanone, 3-methyl-, Muscone, (+/-)-Muscone, Muskone, dl-Muscone (+8 more)

CAS 541-91-3

3-Methylcyclopentadecan-1-one (CAS 541-91-3) is a chemical substance. Key regulatory status: REACH registered, 4 regulatory/inventory lists, cosmetic ingredient cross-reference; source data from EPA ToxValDB, EPA CPDat, AICIS, ECHA REACH.

View cosmetic safety profile for Muscone →

SOURCE noael studies public
NOAEL studies
7
SOURCE chemical inventory jurisdictions
Regulatory lists
4
SOURCE eu clp annex vi
GHS signal
Not classified

Chemical Identity

CAS, identifiers, formula, and alternate names for the matched substance record.

SOURCE DSSTox identifiers 19 fields
Name
3-Methylcyclopentadecan-1-one
CAS Number
541-91-3
DTXSID
DTXSID8052192
Molecular Formula
C16H30O
InChI Key
ALHUZKCOMYUFRB-UHFFFAOYSA-N
Monoisotopic Mass
238.229666
Synonyms
Cyclopentadecanone, 3-methyl-Muscone(+/-)-MusconeMuskonedl-MusconeEINECS 208-795-8FEMA No. 34343-Methylcyclopentadecanone3-Methyl-1-cyclopentadecanone5-Methyl-1-cyclopentadecanoneMethylexaltoneMoschus ketone

Functional Uses

Industrial and product-use categories associated with this substance.

SOURCE EPA CPDat 15 records
DeodorizerFragranceFlavouring and nutrient

Regulatory Lists

Inventory, screening, and regulatory list matches from public chemical databases.

SOURCE EPA CPDat 4 records
ListKeywordSource
IFRA TransparencyIFRAIFRA
food_additive; Substances Added to Food (formerly EAFUS) (2/2019)FDAUnited States Food and Drug Administration (FDA)
consumer_productP&GProctor & Gamble
EuropeEuropean CommissionFl@vis

NOAEL Studies

Toxicology endpoints rendered from public NOAEL study rows.

SOURCE NOAEL studies Showing 7 of 7 studies
ValueUnitEndpointRouteSpeciesSource
5JO79R7S9RUNIIFDA UNII substance identifier--openFDA substances
5JO79R7S9RUNIIFDA UNII substance identifier--openFDA substances
5JO79R7S9RUNIIFDA UNII substance identifier--openFDA substances
5JO79R7S9RUNIIFDA UNII substance identifier--openFDA substances
-%Incidence of positive responsesDermalHumanNTP_ICE_skin_sensitization
20250ug/cm2Induction dose per skin areaDermalHumanNTP_ICE_skin_sensitization
3unitlessRelative reliability scoreDermalHumanNTP_ICE_skin_sensitization

Showing 7 of 7 studies

REACH Registration

Registration status from the ECHA REACH registered substances database.

SOURCE ECHA (EU) 1 records
StatusNameEC NumberLink
Registered3-methylcyclopentadecan-1-one208-795-8ECHA overview →

Australian Status (AICIS)

Australian industrial chemicals inventory status and applicable conditions.

SOURCE AICIS inventory 1 records
Inventory Status
listed

Cosmetic Safety Profile

Same-CAS cosmetic ingredient record for cross-vertical context.

SOURCE CosIng / Ingredients DB
EU Status
permitted
Max
-
Category
musk
View full cosmetic safety profile →

Cannabis Data

Same-CAS cannabis compliance and lab records where available.

SOURCE Cannabis regulatory / lab data efsa substances

1 cannabis record found in efsa substances.

View full cannabis profile →

Frequently Asked Questions

What is the NOAEL for 3-Methylcyclopentadecan-1-one?

3-Methylcyclopentadecan-1-one has 7 NOAEL studies in the database. The lowest reported value is 5JO79R7S9R UNII. Source: openFDA substances.

What regulatory lists include 3-Methylcyclopentadecan-1-one?

3-Methylcyclopentadecan-1-one appears on 4 regulatory/inventory lists including IFRA Transparency, food_additive; Substances Added to Food (formerly EAFUS) (2/2019), consumer_product, and 1 more. Source: EPA CPDat.

Is 3-Methylcyclopentadecan-1-one used in cosmetics?

Yes, 3-Methylcyclopentadecan-1-one is also indexed as a cosmetic ingredient under the name Muscone. View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.

Where does the safety data for 3-Methylcyclopentadecan-1-one come from?

Safety data is sourced from EPA ToxValDB, EPA CPDat, AICIS (Australian Industrial Chemicals Introduction Scheme), EPA DSSTox, ECHA REACH, CosIng / Ingredients DB, cannabis regulatory/lab databases. All data traces to primary regulatory sources and is updated from official government databases.

Is 3-Methylcyclopentadecan-1-one used outside industrial chemicals?

3-Methylcyclopentadecan-1-one also appears in cosmetics, cannabis databases.