What is the NOAEL for Hexadecane?
Hexadecane has 5 NOAEL studies in the database. The lowest reported value is F8Z00SHP6Q UNII. Source: openFDA substances.
NOAEL Data
REACH Registered
Cosmetic Ingredient
Hexadecane
Also known as: 4-01-00-00537, BRN 1736592, EINECS 208-878-9, UNII-F8Z00SHP6Q, CNS
CAS 544-76-3
Hexadecane (CAS 544-76-3) is a chemical substance. Key regulatory status: REACH registered, 7 regulatory/inventory lists, cosmetic ingredient cross-reference; source data from EPA ToxValDB, EPA CPDat, AICIS, ECHA REACH.
Cross-Vertical Regulatory Divergence
Hexadecane is classified GHS Danger (H304, H315) in the chemicals database but is allowed in EU cosmetics.
SOURCE
Cross-vertical comparison
Cosmetics: ingredients.eu_status; Chemicals: ghs_classifications.signal_word/hazard_statement_code
SOURCE
noael studies public
NOAEL studies
5
SOURCE
chemical inventory jurisdictions
Regulatory lists
7
SOURCE
eu clp annex vi
GHS signal
Not classified
Chemical Identity
CAS, identifiers, formula, and alternate names for the matched substance record.
SOURCE
DSSTox identifiers
11 fields
Name
Hexadecane
CAS Number
544-76-3
DTXSID
DTXSID0027195
Molecular Formula
C16H34
InChI Key
DCAYPVUWAIABOU-UHFFFAOYSA-N
Monoisotopic Mass
226.266051
Synonyms
4-01-00-00537BRN 1736592EINECS 208-878-9UNII-F8Z00SHP6QCNS
Functional Uses
Industrial and product-use categories associated with this substance.
SOURCE
EPA CPDat
6 records
FragranceFlavouring and nutrientNo specific technical functionSolvent
Regulatory Lists
Inventory, screening, and regulatory list matches from public chemical databases.
SOURCE
EPA CPDat
7 records
| List | Keyword | Source |
|---|---|---|
| detected; Other direct contact consumer goods; Other indirect contact consumer goods | Danish Environmental Protection Agency | Danish EPA |
| air; Arts and crafts/Office supplies - children's art and toys - modeling clay; detected; emissions; Europe | Danish Environmental Protection Agency | Danish EPA |
| air; emissions; Europe; nondetect; Other direct contact consumer goods | Danish Environmental Protection Agency | Danish EPA |
| air; detected; emissions; Europe; Toys and children's products | Danish Environmental Protection Agency | Danish EPA |
| IFRA Transparency | IFRA | IFRA |
| Europe | European Commission | Fl@vis |
| consumer_product | P&G | Proctor & Gamble |
NOAEL Studies
Toxicology endpoints rendered from public NOAEL study rows.
SOURCE
NOAEL studies
Showing 5 of 5 studies
| Value | Unit | Endpoint | Route | Species | Source |
|---|---|---|---|---|---|
| F8Z00SHP6Q | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| F8Z00SHP6Q | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| F8Z00SHP6Q | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| F8Z00SHP6Q | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| - | unitless | Model Score | - | - | NTP_ICE_endocrine |
Showing 5 of 5 studies
REACH Registration
Registration status from the ECHA REACH registered substances database.
SOURCE
ECHA (EU)
1 records
| Status | Name | EC Number | Link |
|---|---|---|---|
| Registered | Hexadecane | 208-878-9 | ECHA overview → |
Australian Status (AICIS)
Australian industrial chemicals inventory status and applicable conditions.
SOURCE
AICIS inventory
1 records
Inventory Status
listed
Cosmetic Safety Profile
Same-CAS cosmetic ingredient record for cross-vertical context.
SOURCE
CosIng / Ingredients DB
EU Status
permitted
Max
-
Category
Emollient
Pharmaceutical Data
Same-CAS pharmaceutical records from drug and bioactivity sources.
SOURCE
EMBL-EBI ChEMBL
HEXADECANE
ChEMBL Phase
Not listed
Adverse Events
0
Bioactivity
1
Cannabis Data
Same-CAS cannabis compliance and lab records where available.
SOURCE
Cannabis regulatory / lab data
efsa substances
1 cannabis record found in efsa substances.
View full cannabis profile →Frequently Asked Questions
What regulatory lists include Hexadecane?
Hexadecane appears on 7 regulatory/inventory lists including detected; Other direct contact consumer goods; Other indirect contact consumer goods, air; Arts and crafts/Office supplies - children's art and toys - modeling clay; detected; emissions; Europe, air; emissions; Europe; nondetect; Other direct contact consumer goods, and 4 more. Source: EPA CPDat.
Is Hexadecane used in cosmetics?
Yes, Hexadecane is also indexed as a cosmetic ingredient under the name Hexadecane. View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.
Where does the safety data for Hexadecane come from?
Safety data is sourced from EPA ToxValDB, EPA CPDat, AICIS (Australian Industrial Chemicals Introduction Scheme), EPA DSSTox, ECHA REACH, CosIng / Ingredients DB, ChEMBL / DailyMed, cannabis regulatory/lab databases. All data traces to primary regulatory sources and is updated from official government databases.
Does Hexadecane have different safety status in cosmetics vs industrial chemicals?
Hexadecane is classified GHS Danger (H304, H315) in the chemicals database but is allowed in EU cosmetics.
Is Hexadecane used outside industrial chemicals?
Hexadecane also appears in cosmetics, pharmaceutical, cannabis databases.