What is the NOAEL for Methyl 2-hydroxypropanoate?
Methyl 2-hydroxypropanoate has 5 NOAEL studies in the database. The lowest reported value is H10S91526X UNII. Source: openFDA substances.
NOAEL Data
Cosmetic Ingredient
Methyl 2-hydroxypropanoate
Also known as: Propanoic acid, 2-hydroxy-, methyl ester, EINECS 208-930-0, EINECS 218-449-8, 2-Hydroxypropanoic acid methyl ester, Methyl alpha-hydroxypropionate (+7 more)
CAS 547-64-8
Methyl 2-hydroxypropanoate (CAS 547-64-8) is a chemical substance. Key regulatory status: 4 regulatory/inventory lists, cosmetic ingredient cross-reference; source data from EPA ToxValDB, EPA CPDat.
SOURCE
NOAEL studies
NOAEL studies
5
SOURCE
Chemical inventory jurisdictions
Regulatory lists
4
SOURCE
EU CLP Annex VI
GHS signal
Not classified
Chemical Identity
CAS, identifiers, formula, and alternate names for the matched substance record.
SOURCE
DSSTox identifiers
17 fields
Name
Methyl 2-hydroxypropanoate
CAS Number
547-64-8
Molecular Formula
C4H8O3
InChI Key
LPEKGGXMPWTOCB-UHFFFAOYSA-N
Monoisotopic Mass
104.047344
Synonyms
Propanoic acid, 2-hydroxy-, methyl esterEINECS 208-930-0EINECS 218-449-82-Hydroxypropanoic acid methyl esterMethyl alpha-hydroxypropionateNSC 406248(+/-)-Methyl 2-hydroxypropanoate(+/-)-Methyl 2-hydroxypropionate(+/-)-Methyl lactateDL-Methyl lactatemethyl lactatemethyl 2-hydroxypropionate
Functional Uses
Industrial and product-use categories associated with this substance.
SOURCE
EPA CPDat
7 records
SolventFlavouring and nutrientFragranceDeodorizer
Regulatory Lists
Inventory, screening, and regulatory list matches from public chemical databases.
SOURCE
EPA CPDat
4 records
| List | Keyword | Source |
|---|---|---|
| Cons electronics mech appliances and machinery; detected; Europe | Danish EPA | Danish EPA |
| Cons electronics mech appliances and machinery; detected; Europe | Danish EPA | Danish EPA |
| artificial_saliva; detected; emissions; Europe; Toys and children's products | Danish Environmental Protection Agency | Danish EPA |
| artificial_saliva; detected; emissions; Europe; Toys and children's products | Danish Environmental Protection Agency | Danish EPA |
NOAEL Studies
Toxicology endpoints rendered from public NOAEL study rows.
SOURCE
NOAEL studies
Showing 5 of 5 studies
| Value | Unit | Endpoint | Route | Species | Source |
|---|---|---|---|---|---|
| H10S91526X | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| >2000 | mg/kg bw | LD50 | oral | Rat | NTP ICE acute oral |
| =75 | mg/m3 | LOAEL | - | Rat | WHO/JECFA |
| =0.5 | mg/kg bw | NOAEL | oral | - | WHO/JECFA |
| =200 | mg/m3 | NOAEL | inhalation | - | WHO/JECFA |
Showing 5 of 5 studies
Cosmetic Safety Profile
Same-CAS cosmetic ingredient record for cross-vertical context.
SOURCE
CosIng / Ingredients DB
EU Status
permitted
Max
-
Category
Fragrance
Pharmaceutical Data
Same-CAS pharmaceutical records from drug and bioactivity sources.
SOURCE
ChEMBL / DailyMed
CHEMBL3183351
ChEMBL Phase
Not listed
Adverse Events
0
Bioactivity
0
Frequently Asked Questions
What regulatory lists include Methyl 2-hydroxypropanoate?
Methyl 2-hydroxypropanoate appears on 2 regulatory/inventory lists including Cons electronics mech appliances and machinery; detected; Europe, artificial_saliva; detected; emissions; Europe; Toys and children's products. Source: EPA CPDat.
Is Methyl 2-hydroxypropanoate used in cosmetics?
Yes, Methyl 2-hydroxypropanoate is also indexed as a cosmetic ingredient under the name Methyl Lactate. View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.
Where does the safety data for Methyl 2-hydroxypropanoate come from?
Safety data is sourced from EPA ToxValDB, EPA CPDat, EPA DSSTox, CosIng / Ingredients DB, ChEMBL / DailyMed. All data traces to primary regulatory sources and is updated from official government databases.
Is Methyl 2-hydroxypropanoate used outside industrial chemicals?
Methyl 2-hydroxypropanoate also appears in cosmetics, pharmaceutical databases.