NOAEL Data Cosmetic Ingredient

2'-Hydroxy-4'-methoxyacetophenone

Also known as: Ethanone, 1-(2-hydroxy-4-methoxyphenyl)-, 1-(2-Hydroxy-4-methoxyphenyl)ethan-1-one, 1-(4-Methoxy-2-hydroxyphenyl)ethanone, 4-08-00-01793, BRN 1282794 (+4 more)

CAS 552-41-0

2'-Hydroxy-4'-methoxyacetophenone (CAS 552-41-0) is a chemical substance. Key regulatory status: cosmetic ingredient cross-reference; source data from EPA ToxValDB, EPA CPDat.

View cosmetic safety profile for PAEONOL →

SOURCE noael studies public
NOAEL studies
4
SOURCE chemical inventory jurisdictions
Regulatory lists
0
SOURCE eu clp annex vi
GHS signal
Not classified

Chemical Identity

CAS, identifiers, formula, and alternate names for the matched substance record.

SOURCE DSSTox identifiers 15 fields
Name
2'-Hydroxy-4'-methoxyacetophenone
CAS Number
552-41-0
DTXSID
DTXSID1022059
Molecular Formula
C9H10O3
InChI Key
UILPJVPSNHJFIK-UHFFFAOYSA-N
Monoisotopic Mass
166.062994
Synonyms
Ethanone, 1-(2-hydroxy-4-methoxyphenyl)-1-(2-Hydroxy-4-methoxyphenyl)ethan-1-one1-(4-Methoxy-2-hydroxyphenyl)ethanone4-08-00-01793BRN 1282794EINECS 209-012-2Resacetophenone, 4-O-methyl esterResacetophenone-4-methyl etherUNII-3R834EPI82

Functional Uses

Industrial and product-use categories associated with this substance.

SOURCE EPA CPDat 2 records
AntioxidantSoftener and conditioner

NOAEL Studies

Toxicology endpoints rendered from public NOAEL study rows.

SOURCE NOAEL studies Showing 4 of 4 studies
ValueUnitEndpointRouteSpeciesSource
3R834EPI82UNIIFDA UNII substance identifier--openFDA substances
3R834EPI82UNIIFDA UNII substance identifier--openFDA substances
3R834EPI82UNIIFDA UNII substance identifier--openFDA substances
3R834EPI82UNIIFDA UNII substance identifier--openFDA substances

Showing 4 of 4 studies

Cosmetic Safety Profile

Same-CAS cosmetic ingredient record for cross-vertical context.

SOURCE CosIng / Ingredients DB
EU Status
permitted
Max
-
Category
Antioxidant
View full cosmetic safety profile →

Pharmaceutical Data

Same-CAS pharmaceutical records from drug and bioactivity sources.

SOURCE EMBL-EBI ChEMBL PAEONOL
ChEMBL Phase
Not listed
Adverse Events
0
Bioactivity
2
View full pharmaceutical profile →

Frequently Asked Questions

What is the NOAEL for 2'-Hydroxy-4'-methoxyacetophenone?

2'-Hydroxy-4'-methoxyacetophenone has 4 NOAEL studies in the database. The lowest reported value is 3R834EPI82 UNII. Source: openFDA substances.

Is 2'-Hydroxy-4'-methoxyacetophenone used in cosmetics?

Yes, 2'-Hydroxy-4'-methoxyacetophenone is also indexed as a cosmetic ingredient under the name PAEONOL. View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.

Where does the safety data for 2'-Hydroxy-4'-methoxyacetophenone come from?

Safety data is sourced from EPA ToxValDB, EPA CPDat, EPA DSSTox, CosIng / Ingredients DB, ChEMBL / DailyMed. All data traces to primary regulatory sources and is updated from official government databases.

Is 2'-Hydroxy-4'-methoxyacetophenone used outside industrial chemicals?

2'-Hydroxy-4'-methoxyacetophenone also appears in cosmetics, pharmaceutical databases.