What is the NOAEL for Ethanedioic acid, dimethyl ester?
Ethanedioic acid, dimethyl ester has 4 NOAEL studies in the database. The lowest reported value is IQ3Q79344S UNII. Source: openFDA substances.
NOAEL Data
REACH Registered
Cosmetic Ingredient
Ethanedioic acid, dimethyl ester
Also known as: EINECS 209-053-6, Oxalic acid dimethyl ester, UNII-IQ3Q79344S
CAS 553-90-2
Ethanedioic acid, dimethyl ester (CAS 553-90-2) is a chemical substance. Key regulatory status: REACH registered, cosmetic ingredient cross-reference; source data from EPA ToxValDB, EPA CPDat, AICIS, ECHA REACH.
Cross-Vertical Regulatory Divergence
Ethanedioic acid, dimethyl ester is prohibited in EU cosmetics but has active industrial GHS classifications (H302, H314, H315, H318, H319, H373).
SOURCE
Cross-vertical comparison
Cosmetics: ingredients.eu_status; Chemicals: ghs_classifications.signal_word/hazard_statement_code
SOURCE
noael studies public
NOAEL studies
4
SOURCE
chemical inventory jurisdictions
Regulatory lists
0
SOURCE
eu clp annex vi
GHS signal
Not classified
Chemical Identity
CAS, identifiers, formula, and alternate names for the matched substance record.
SOURCE
DSSTox identifiers
9 fields
Name
Ethanedioic acid, dimethyl ester
CAS Number
553-90-2
DTXSID
DTXSID9060287
Molecular Formula
C4H6O4
InChI Key
LOMVENUNSWAXEN-UHFFFAOYSA-N
Monoisotopic Mass
118.026609
Synonyms
EINECS 209-053-6Oxalic acid dimethyl esterUNII-IQ3Q79344S
Functional Uses
Industrial and product-use categories associated with this substance.
SOURCE
EPA CPDat
3 records
SolventPlasticizerChelating agent
NOAEL Studies
Toxicology endpoints rendered from public NOAEL study rows.
SOURCE
NOAEL studies
Showing 4 of 4 studies
| Value | Unit | Endpoint | Route | Species | Source |
|---|---|---|---|---|---|
| IQ3Q79344S | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| IQ3Q79344S | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| IQ3Q79344S | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| IQ3Q79344S | UNII | FDA UNII substance identifier | - | - | openFDA substances |
Showing 4 of 4 studies
REACH Registration
Registration status from the ECHA REACH registered substances database.
SOURCE
ECHA (EU)
1 records
| Status | Name | EC Number | Link |
|---|---|---|---|
| Registered | Dimethyl oxalate | 209-053-6 | ECHA overview → |
Australian Status (AICIS)
Australian industrial chemicals inventory status and applicable conditions.
SOURCE
AICIS inventory
1 records
Inventory Status
listed
Cosmetic Safety Profile
Same-CAS cosmetic ingredient record for cross-vertical context.
SOURCE
CosIng / Ingredients DB
EU Status
prohibited
Max
-
Category
Fragrance
Frequently Asked Questions
Is Ethanedioic acid, dimethyl ester used in cosmetics?
Yes, Ethanedioic acid, dimethyl ester is also indexed as a cosmetic ingredient under the name Dimethyl Oxalate. View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.
Where does the safety data for Ethanedioic acid, dimethyl ester come from?
Safety data is sourced from EPA ToxValDB, EPA CPDat, AICIS (Australian Industrial Chemicals Introduction Scheme), EPA DSSTox, ECHA REACH, CosIng / Ingredients DB. All data traces to primary regulatory sources and is updated from official government databases.
Does Ethanedioic acid, dimethyl ester have different safety status in cosmetics vs industrial chemicals?
Ethanedioic acid, dimethyl ester is prohibited in EU cosmetics but has active industrial GHS classifications (H302, H314, H315, H318, H319, H373).
Is Ethanedioic acid, dimethyl ester used outside industrial chemicals?
Ethanedioic acid, dimethyl ester also appears in cosmetics databases.