What is the NOAEL for Magnesium stearate?
Magnesium stearate has 5 NOAEL studies in the database. The lowest reported value is 70097M6I30 UNII. Source: openFDA substances.
NOAEL Data
Cosmetic Ingredient
Magnesium stearate
Also known as: Octadecanoic acid, magnesium salt, AFCO-Chem MGS, Aurabrite MA 76, Daiwax SMO, EM 100 (salt) (+11 more)
CAS 557-04-0
Magnesium stearate (CAS 557-04-0) is a chemical substance. Key regulatory status: 9 regulatory/inventory lists, cosmetic ingredient cross-reference; source data from EPA ToxValDB, EPA CPDat, AICIS, ILO ICSC.
SOURCE
noael studies public
NOAEL studies
5
SOURCE
chemical inventory jurisdictions
Regulatory lists
9
SOURCE
eu clp annex vi
GHS signal
Not classified
Chemical Identity
CAS, identifiers, formula, and alternate names for the matched substance record.
SOURCE
DSSTox identifiers
22 fields
Name
Magnesium stearate
CAS Number
557-04-0
DTXSID
DTXSID2027208
Molecular Formula
2C18H36O2.Mg
InChI Key
HQKMJHAJHXVSDF-UHFFFAOYSA-L
Monoisotopic Mass
592.528102
Synonyms
Octadecanoic acid, magnesium saltAFCO-Chem MGSAurabrite MA 76Daiwax SMOEM 100 (salt)HyQualKemilub EM-F-VLiga MF 2VLigastar MG 700Palmstar 325BP/EPParteck LUBParteck LUB-MST
ICSC Chemical Safety
International Chemical Safety Card hazard and exposure summary.
SOURCE
ILO/WHO International Chemical Safety Cards
1 records
| Field | Value |
|---|---|
| Routes of Exposure | The substance can be absorbed into the body by inhalation. |
Functional Uses
Industrial and product-use categories associated with this substance.
SOURCE
EPA CPDat
60 records
Surfactant (surface active agent)Anti-caking agentDyeFillerHumectantThickening agentBinderLubricating agentFlavouring and nutrientAnti-adhesive/cohesiveProcessing aids not otherwise specified
Regulatory Lists
Inventory, screening, and regulatory list matches from public chemical databases.
SOURCE
EPA CPDat
9 records
| List | Keyword | Source |
|---|---|---|
| active_ingredient; animal_products; Europe; pharmaceutical; residue | EU | CPCat |
| food_additive; Substances Added to Food (formerly EAFUS) (2/2019) | FDA | United States Food and Drug Administration (FDA) |
| SCIL (9/2019) | USEPA | Safer Chemical Ingredients List |
| Canada; pharmaceutical | DrugBank | DrugBank |
| Cleaning products and household care - dishwasher and dishes - automatic dishwashing detergent; Europe | Danish EPA | Danish EPA |
| Canada; consumer_product; Substances in Products - Canada (4/2014) | Government of Canada | CPCat |
| inert_ingredient; Pesticides | EPA | CPCat |
| inert_ingredient; Pesticides | EPA | CPCat |
| inert_ingredient; non_food_use; Pesticides | EPA | CPCat |
NOAEL Studies
Toxicology endpoints rendered from public NOAEL study rows.
SOURCE
NOAEL studies
Showing 5 of 5 studies
| Value | Unit | Endpoint | Route | Species | Source |
|---|---|---|---|---|---|
| 70097M6I30 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 70097M6I30 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 70097M6I30 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 70097M6I30 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| >2.5 | mg/kg bw/day | NOAEL | oral | Rabbit | ToxValDB_ECHA_IUCLID |
Showing 5 of 5 studies
Australian Status (AICIS)
Australian industrial chemicals inventory status and applicable conditions.
SOURCE
AICIS inventory
1 records
Inventory Status
listed
Cosmetic Safety Profile
Same-CAS cosmetic ingredient record for cross-vertical context.
SOURCE
CosIng / Ingredients DB
EU Status
permitted
Max
-
Category
emollient
Pharmaceutical Data
Same-CAS pharmaceutical records from drug and bioactivity sources.
SOURCE
EMBL-EBI ChEMBL
MAGNESIUM STEARATE
ChEMBL Phase
1
Adverse Events
0
Bioactivity
0
Food Safety Data
Same-CAS food additive, ADI, and GRAS records where available.
SOURCE
EFSA / FDA GRAS
1 records
E470b — ADI: NOT SPECIFIED mg/kg bw
View full food safety profile →Frequently Asked Questions
What regulatory lists include Magnesium stearate?
Magnesium stearate appears on 8 regulatory/inventory lists including active_ingredient; animal_products; Europe; pharmaceutical; residue, food_additive; Substances Added to Food (formerly EAFUS) (2/2019), SCIL (9/2019), and 5 more. Source: EPA CPDat.
Is Magnesium stearate used in cosmetics?
Yes, Magnesium stearate is also indexed as a cosmetic ingredient under the name Magnesium Stearate. View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.
Where does the safety data for Magnesium stearate come from?
Safety data is sourced from EPA ToxValDB, EPA CPDat, AICIS (Australian Industrial Chemicals Introduction Scheme), EPA DSSTox, ILO/WHO ICSC, CosIng / Ingredients DB, ChEMBL / DailyMed, EFSA / FDA GRAS. All data traces to primary regulatory sources and is updated from official government databases.
Is Magnesium stearate used outside industrial chemicals?
Magnesium stearate also appears in cosmetics, pharmaceutical, food safety databases.