What is the NOAEL for C.I. Pigment Yellow 16?
C.I. Pigment Yellow 16 has 4 NOAEL studies in the database. The lowest reported value is R3896P1A0H UNII. Source: openFDA substances.
NOAEL Data
Cosmetic Ingredient
C.I. Pigment Yellow 16
Also known as: Butanamide, N,N'-(3,3'-dimethyl[1,1'-biphenyl]-4,4'-diyl)bis[2-[2-(2,4-dichlorophenyl)diazenyl]-3-oxo-, N,N'-(3,3'-Dimethyl(1,1'-biphenyl)-4,4'-diyl)bis(2-((2,4-dichlorophenyl)azo)-3-oxobutyramide), Butanamide, N,N'-(3,3'-dimethyl(1,1'-biphenyl)-4,4'-diyl)bis(2-((2,4-dichlorophenyl)azo)-3-oxo-, Chromatex Yellow JN, EINECS 227-783-3 (+15 more)
CAS 5979-28-2
C.I. Pigment Yellow 16 (CAS 5979-28-2) is a chemical substance. Key regulatory status: 2 regulatory/inventory lists, cosmetic ingredient cross-reference; source data from EPA ToxValDB, EPA CPDat, AICIS.
View cosmetic safety profile for CI 20040 (Pigment Yellow 16) →
Cross-Vertical Regulatory Divergence
C.I. Pigment Yellow 16 is classified GHS Danger (H350) in the chemicals database but is restricted in EU cosmetics at max Annex IV listed; permitted as colorant exclusively in rinse-off cosmetics; no maximum concentration specified.
SOURCE
Cross-vertical comparison
Cosmetics: ingredients.eu_status/eu_max; Chemicals: ghs_classifications.signal_word/hazard_statement_code
SOURCE
noael studies public
NOAEL studies
4
SOURCE
chemical inventory jurisdictions
Regulatory lists
2
SOURCE
eu clp annex vi
GHS signal
Not classified
Chemical Identity
CAS, identifiers, formula, and alternate names for the matched substance record.
SOURCE
DSSTox identifiers
26 fields
Name
C.I. Pigment Yellow 16
CAS Number
5979-28-2
DTXSID
DTXSID6021452
Molecular Formula
C34H28Cl4N6O4
InChI Key
JFMYRCRXYIIGBB-UHFFFAOYSA-N
Monoisotopic Mass
724.092614
Synonyms
Butanamide, N,N'-(3,3'-dimethyl[1,1'-biphenyl]-4,4'-diyl)bis[2-[2-(2,4-dichlorophenyl)diazenyl]-3-oxo-N,N'-(3,3'-Dimethyl(1,1'-biphenyl)-4,4'-diyl)bis(2-((2,4-dichlorophenyl)azo)-3-oxobutyramide)Butanamide, N,N'-(3,3'-dimethyl(1,1'-biphenyl)-4,4'-diyl)bis(2-((2,4-dichlorophenyl)azo)-3-oxo-Chromatex Yellow JNEINECS 227-783-3Helio Fast Yellow FPVHostaperm Yellow NCGIrgalite Fast Yellow GCLight Yellow JNNSC 521238Permanent Yellow NCGPigment Fast Yellow 3GL
Functional Uses
Industrial and product-use categories associated with this substance.
SOURCE
EPA CPDat
2 records
Dye
Regulatory Lists
Inventory, screening, and regulatory list matches from public chemical databases.
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EPA CPDat
2 records
| List | Keyword | Source |
|---|---|---|
| inert_ingredient; non_food_use; Pesticides | EPA | CPCat |
| Europe; Personal care | European Commission | CosIng |
NOAEL Studies
Toxicology endpoints rendered from public NOAEL study rows.
SOURCE
NOAEL studies
Showing 4 of 4 studies
| Value | Unit | Endpoint | Route | Species | Source |
|---|---|---|---|---|---|
| R3896P1A0H | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| R3896P1A0H | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| R3896P1A0H | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| R3896P1A0H | UNII | FDA UNII substance identifier | - | - | openFDA substances |
Showing 4 of 4 studies
Australian Status (AICIS)
Australian industrial chemicals inventory status and applicable conditions.
SOURCE
AICIS inventory
1 records
Inventory Status
listed
Cosmetic Safety Profile
Same-CAS cosmetic ingredient record for cross-vertical context.
SOURCE
CosIng / Ingredients DB
EU Status
restricted
Max
Annex IV listed; permitted as colorant exclusively in rinse-off cosmetics; no maximum concentration specified
Category
Colorants
Frequently Asked Questions
What regulatory lists include C.I. Pigment Yellow 16?
C.I. Pigment Yellow 16 appears on 2 regulatory/inventory lists including inert_ingredient; non_food_use; Pesticides, Europe; Personal care. Source: EPA CPDat.
Is C.I. Pigment Yellow 16 used in cosmetics?
Yes, C.I. Pigment Yellow 16 is also indexed as a cosmetic ingredient under the name CI 20040 (Pigment Yellow 16). View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.
Where does the safety data for C.I. Pigment Yellow 16 come from?
Safety data is sourced from EPA ToxValDB, EPA CPDat, AICIS (Australian Industrial Chemicals Introduction Scheme), EPA DSSTox, CosIng / Ingredients DB. All data traces to primary regulatory sources and is updated from official government databases.
Does C.I. Pigment Yellow 16 have different safety status in cosmetics vs industrial chemicals?
C.I. Pigment Yellow 16 is classified GHS Danger (H350) in the chemicals database but is restricted in EU cosmetics at max Annex IV listed; permitted as colorant exclusively in rinse-off cosmetics; no maximum concentration specified.
Is C.I. Pigment Yellow 16 used outside industrial chemicals?
C.I. Pigment Yellow 16 also appears in cosmetics databases.