What is the NOAEL for Creatinine?
Creatinine has 4 NOAEL studies in the database. The lowest reported value is AYI8EX34EU UNII. Source: openFDA substances.
NOAEL Data
REACH Registered
Cosmetic Ingredient
Creatinine
Also known as: Creatinine,heated, EINECS 200-466-7, UNII-AYI8EX34EU, 2-amino-1-methyl-5H-imidazol-4-one, Creatine anhydride (+2 more)
CAS 60-27-5
Creatinine (CAS 60-27-5) is a chemical substance. Key regulatory status: REACH registered, 1 regulatory/inventory list, cosmetic ingredient cross-reference; source data from EPA ToxValDB, EPA CPDat, ECHA REACH.
View cosmetic safety profile for 1-Methylhydantoin-2-imide (Creatinine) →
SOURCE
noael studies public
NOAEL studies
4
SOURCE
chemical inventory jurisdictions
Regulatory lists
1
SOURCE
eu clp annex vi
GHS signal
Not classified
Chemical Identity
CAS, identifiers, formula, and alternate names for the matched substance record.
SOURCE
DSSTox identifiers
13 fields
Name
Creatinine
CAS Number
60-27-5
DTXSID
DTXSID8045987
Molecular Formula
C4H7N3O
InChI Key
DDRJAANPRJIHGJ-UHFFFAOYSA-N
Monoisotopic Mass
113.058912
Synonyms
Creatinine,heatedEINECS 200-466-7UNII-AYI8EX34EU2-amino-1-methyl-5H-imidazol-4-oneCreatine anhydrideKreatinincreatinina
Functional Uses
Industrial and product-use categories associated with this substance.
SOURCE
EPA CPDat
1 records
Softener and conditioner
Regulatory Lists
Inventory, screening, and regulatory list matches from public chemical databases.
SOURCE
EPA CPDat
1 records
| List | Keyword | Source |
|---|---|---|
| Canada; pharmaceutical | DrugBank | DrugBank |
NOAEL Studies
Toxicology endpoints rendered from public NOAEL study rows.
SOURCE
NOAEL studies
Showing 4 of 4 studies
| Value | Unit | Endpoint | Route | Species | Source |
|---|---|---|---|---|---|
| AYI8EX34EU | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| AYI8EX34EU | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| AYI8EX34EU | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| AYI8EX34EU | UNII | FDA UNII substance identifier | - | - | openFDA substances |
Showing 4 of 4 studies
REACH Registration
Registration status from the ECHA REACH registered substances database.
SOURCE
ECHA (EU)
1 records
| Status | Name | EC Number | Link |
|---|---|---|---|
| Registered | 2-imino-1-methylimidazolidin-4-one | 200-466-7 | ECHA overview → |
Cosmetic Safety Profile
Same-CAS cosmetic ingredient record for cross-vertical context.
SOURCE
CosIng / Ingredients DB
EU Status
permitted
Max
-
Category
Skin Conditioning
Pharmaceutical Data
Same-CAS pharmaceutical records from drug and bioactivity sources.
SOURCE
EMBL-EBI ChEMBL
CREATININE
ChEMBL Phase
3
Adverse Events
41
Bioactivity
3
Frequently Asked Questions
What regulatory lists include Creatinine?
Creatinine appears on 1 regulatory/inventory list including Canada; pharmaceutical. Source: EPA CPDat.
Is Creatinine used in cosmetics?
Yes, Creatinine is also indexed as a cosmetic ingredient under the name 1-Methylhydantoin-2-imide (Creatinine). View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.
Where does the safety data for Creatinine come from?
Safety data is sourced from EPA ToxValDB, EPA CPDat, EPA DSSTox, ECHA REACH, CosIng / Ingredients DB, ChEMBL / DailyMed. All data traces to primary regulatory sources and is updated from official government databases.
Is Creatinine used outside industrial chemicals?
Creatinine also appears in cosmetics, pharmaceutical databases.