What is the NOAEL for Polyoxyethylene 2,6,8-trimethyl-4-nonyl ether?
Polyoxyethylene 2,6,8-trimethyl-4-nonyl ether has 13 NOAEL studies in the database. The lowest reported value is 0URO31WRVV UNII. Source: openFDA substances.
NOAEL Data
Cosmetic Ingredient
Polyoxyethylene 2,6,8-trimethyl-4-nonyl ether
Also known as: Poly(oxy-1,2-ethanediyl), .alpha.-[3,5-dimethyl-1-(2-methylpropyl)hexyl]-.omega.-hydroxy-, alpha-[3,5-Dimethyl-1-(2-methylpropyl)hexyl]-omega-hydroxy-poly(oxy-1,2-ethandiyl), Poly(oxy-1,2-ethanediyl), alpha-(3,5-dimethyl-1-(2-methylpropyl)hexyl)-omega-hydroxy-, alpha-Alkyl-omega-hydroxypoly(oxypropylene) and/or poly(oxyethylene) polymers where the alkyl chain contains a minimum of six carbons, minimum number average molecular weight (in amu) 1,100, Glycols, polyethylene mono(trimethylnonyl) (+3 more)
CAS 60828-78-6
Polyoxyethylene 2,6,8-trimethyl-4-nonyl ether (CAS 60828-78-6) is a chemical substance. Key regulatory status: 5 regulatory/inventory lists, cosmetic ingredient cross-reference; source data from EPA ToxValDB, EPA CPDat, AICIS.
Cross-Vertical Regulatory Divergence
Polyoxyethylene 2,6,8-trimethyl-4-nonyl ether is classified GHS Danger (H318, H319, H412) in the chemicals database but is allowed in EU cosmetics.
SOURCE
Cross-vertical comparison
Cosmetics: ingredients.eu_status; Chemicals: ghs_classifications.signal_word/hazard_statement_code
SOURCE
noael studies public
NOAEL studies
13
SOURCE
chemical inventory jurisdictions
Regulatory lists
5
SOURCE
eu clp annex vi
GHS signal
Not classified
Chemical Identity
CAS, identifiers, formula, and alternate names for the matched substance record.
SOURCE
DSSTox identifiers
11 fields
Name
Polyoxyethylene 2,6,8-trimethyl-4-nonyl ether
CAS Number
60828-78-6
DTXSID
DTXSID9049829
Synonyms
Poly(oxy-1,2-ethanediyl), .alpha.-[3,5-dimethyl-1-(2-methylpropyl)hexyl]-.omega.-hydroxy-alpha-[3,5-Dimethyl-1-(2-methylpropyl)hexyl]-omega-hydroxy-poly(oxy-1,2-ethandiyl)Poly(oxy-1,2-ethanediyl), alpha-(3,5-dimethyl-1-(2-methylpropyl)hexyl)-omega-hydroxy-alpha-Alkyl-omega-hydroxypoly(oxypropylene) and/or poly(oxyethylene) polymers where the alkyl chain contains a minimum of six carbons, minimum number average molecular weight (in amu) 1,100Glycols, polyethylene mono(trimethylnonyl)Poly(oxy-1,2-ethanediyl)-alpha-(3,5-dimethyl-1-(2-methylpropyl)hexyl)-omega-hydroxy-Tergitol TMN-6Polyethylene glycol mono(3,5-dimethyl-1-isobutylhexyl) ether
Functional Uses
Industrial and product-use categories associated with this substance.
SOURCE
EPA CPDat
27 records
Surfactant (surface active agent)EmulsifierFragranceBinderCleaning agentWetting agent (non-aqueous)
Regulatory Lists
Inventory, screening, and regulatory list matches from public chemical databases.
SOURCE
EPA CPDat
5 records
| List | Keyword | Source |
|---|---|---|
| consumer_product; Europe | Danish Environmental Protection Agency | Danish EPA |
| IFRA Transparency | IFRA | IFRA |
| fracking; water | NY Department of Conservation | CPCat |
| inert_ingredient; Pesticides | EPA | CPCat |
| inert_ingredient; non_food_use; Pesticides | EPA | CPCat |
NOAEL Studies
Toxicology endpoints rendered from public NOAEL study rows.
SOURCE
NOAEL studies
Showing 13 of 13 studies
| Value | Unit | Endpoint | Route | Species | Source |
|---|---|---|---|---|---|
| 0URO31WRVV | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 0URO31WRVV | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 0URO31WRVV | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 0URO31WRVV | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 52587ZU1O9 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 52587ZU1O9 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 52587ZU1O9 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 52587ZU1O9 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| K6BVH271CZ | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| K6BVH271CZ | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| K6BVH271CZ | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| K6BVH271CZ | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| =5650 | mg/kg bw | LD50 | oral | Rat | NTP_ICE_acute_oral |
Showing 13 of 13 studies
Australian Status (AICIS)
Australian industrial chemicals inventory status and applicable conditions.
SOURCE
AICIS inventory
1 records
Inventory Status
listed
Cosmetic Safety Profile
Same-CAS cosmetic ingredient record for cross-vertical context.
SOURCE
CosIng / Ingredients DB
EU Status
permitted
Max
-
Category
Surfactant
Frequently Asked Questions
What regulatory lists include Polyoxyethylene 2,6,8-trimethyl-4-nonyl ether?
Polyoxyethylene 2,6,8-trimethyl-4-nonyl ether appears on 5 regulatory/inventory lists including consumer_product; Europe, IFRA Transparency, fracking; water, and 2 more. Source: EPA CPDat.
Is Polyoxyethylene 2,6,8-trimethyl-4-nonyl ether used in cosmetics?
Yes, Polyoxyethylene 2,6,8-trimethyl-4-nonyl ether is also indexed as a cosmetic ingredient under the name Isolaureth-10. View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.
Where does the safety data for Polyoxyethylene 2,6,8-trimethyl-4-nonyl ether come from?
Safety data is sourced from EPA ToxValDB, EPA CPDat, AICIS (Australian Industrial Chemicals Introduction Scheme), EPA DSSTox, CosIng / Ingredients DB. All data traces to primary regulatory sources and is updated from official government databases.
Does Polyoxyethylene 2,6,8-trimethyl-4-nonyl ether have different safety status in cosmetics vs industrial chemicals?
Polyoxyethylene 2,6,8-trimethyl-4-nonyl ether is classified GHS Danger (H318, H319, H412) in the chemicals database but is allowed in EU cosmetics.
Is Polyoxyethylene 2,6,8-trimethyl-4-nonyl ether used outside industrial chemicals?
Polyoxyethylene 2,6,8-trimethyl-4-nonyl ether also appears in cosmetics databases.