What is the NOAEL for 2-Phenylpropan-2-ol?
2-Phenylpropan-2-ol has 7 NOAEL studies in the database. The lowest reported value is JE030BGE05 UNII. Source: openFDA substances.
NOAEL Data
REACH Registered
Cosmetic Ingredient
2-Phenylpropan-2-ol
Also known as: Benzenemethanol, .alpha.,.alpha.-dimethyl-, 4-06-00-03219, BRN 1905012, alpha,alpha-Dimethylbenzyl alcohol, EINECS 210-539-5 (+4 more)
CAS 617-94-7
2-Phenylpropan-2-ol (CAS 617-94-7) is a chemical substance. Key regulatory status: REACH registered, 6 regulatory/inventory lists, cosmetic ingredient cross-reference; source data from EPA ToxValDB, EPA CPDat, AICIS, ECHA REACH.
Cross-Vertical Regulatory Divergence
2-Phenylpropan-2-ol is classified GHS Danger (H302, H315, H319, H311) in the chemicals database but is allowed in EU cosmetics.
SOURCE
Cross-vertical comparison
Cosmetics: ingredients.eu_status; Chemicals: ghs_classifications.signal_word/hazard_statement_code
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noael studies public
NOAEL studies
7
SOURCE
chemical inventory jurisdictions
Regulatory lists
6
SOURCE
eu clp annex vi
GHS signal
Not classified
Chemical Identity
CAS, identifiers, formula, and alternate names for the matched substance record.
SOURCE
DSSTox identifiers
15 fields
Name
2-Phenylpropan-2-ol
CAS Number
617-94-7
DTXSID
DTXSID3027247
Molecular Formula
C9H12O
InChI Key
BDCFWIDZNLCTMF-UHFFFAOYSA-N
Monoisotopic Mass
136.088815
Synonyms
Benzenemethanol, .alpha.,.alpha.-dimethyl-4-06-00-03219BRN 1905012alpha,alpha-Dimethylbenzyl alcoholEINECS 210-539-5UNII-JE030BGE05alpha,alpha-dimethylbenzenemethanolalpha,alpha-dimethylbenzyl aldoholalpha-cumyl alcohol
Functional Uses
Industrial and product-use categories associated with this substance.
SOURCE
EPA CPDat
3 records
FragranceFlavouring and nutrient
Regulatory Lists
Inventory, screening, and regulatory list matches from public chemical databases.
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EPA CPDat
6 records
| List | Keyword | Source |
|---|---|---|
| IFRA Transparency | IFRA | IFRA |
| Europe | European Commission | Fl@vis |
| Cons electronics mech appliances and machinery; detected; Europe | Danish EPA | Danish EPA |
| air; detected; emissions; Europe; Other indirect contact consumer goods | Danish Environmental Protection Agency | Danish EPA |
| detected; Europe; Toys and children's products | Danish Environmental Protection Agency | Danish EPA |
| detected; Europe; Toys and children's products | Danish Environmental Protection Agency | Danish EPA |
NOAEL Studies
Toxicology endpoints rendered from public NOAEL study rows.
SOURCE
NOAEL studies
Showing 7 of 7 studies
| Value | Unit | Endpoint | Route | Species | Source |
|---|---|---|---|---|---|
| JE030BGE05 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| JE030BGE05 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| JE030BGE05 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| JE030BGE05 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| - | % | Incidence of positive responses | Dermal | Human | NTP_ICE_skin_sensitization |
| 2700 | ug/cm2 | Induction dose per skin area | Dermal | Human | NTP_ICE_skin_sensitization |
| 3 | unitless | Relative reliability score | Dermal | Human | NTP_ICE_skin_sensitization |
Showing 7 of 7 studies
REACH Registration
Registration status from the ECHA REACH registered substances database.
SOURCE
ECHA (EU)
1 records
| Status | Name | EC Number | Link |
|---|---|---|---|
| Registered | 2-phenylpropan-2-ol | 210-539-5 | ECHA overview → |
Australian Status (AICIS)
Australian industrial chemicals inventory status and applicable conditions.
SOURCE
AICIS inventory
1 records
Inventory Status
listed
Cosmetic Safety Profile
Same-CAS cosmetic ingredient record for cross-vertical context.
SOURCE
CosIng / Ingredients DB
EU Status
permitted
Max
-
Category
Fragrance
Pharmaceutical Data
Same-CAS pharmaceutical records from drug and bioactivity sources.
SOURCE
EMBL-EBI ChEMBL
CHEMBL3185495
ChEMBL Phase
Not listed
Adverse Events
0
Bioactivity
0
Cannabis Data
Same-CAS cannabis compliance and lab records where available.
SOURCE
Cannabis regulatory / lab data
efsa substances
1 cannabis record found in efsa substances.
View full cannabis profile →Frequently Asked Questions
What regulatory lists include 2-Phenylpropan-2-ol?
2-Phenylpropan-2-ol appears on 5 regulatory/inventory lists including IFRA Transparency, Europe, Cons electronics mech appliances and machinery; detected; Europe, and 2 more. Source: EPA CPDat.
Is 2-Phenylpropan-2-ol used in cosmetics?
Yes, 2-Phenylpropan-2-ol is also indexed as a cosmetic ingredient under the name Dimethylphenyl Carbinol. View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.
Where does the safety data for 2-Phenylpropan-2-ol come from?
Safety data is sourced from EPA ToxValDB, EPA CPDat, AICIS (Australian Industrial Chemicals Introduction Scheme), EPA DSSTox, ECHA REACH, CosIng / Ingredients DB, ChEMBL / DailyMed, cannabis regulatory/lab databases. All data traces to primary regulatory sources and is updated from official government databases.
Does 2-Phenylpropan-2-ol have different safety status in cosmetics vs industrial chemicals?
2-Phenylpropan-2-ol is classified GHS Danger (H302, H315, H319, H311) in the chemicals database but is allowed in EU cosmetics.
Is 2-Phenylpropan-2-ol used outside industrial chemicals?
2-Phenylpropan-2-ol also appears in cosmetics, pharmaceutical, cannabis databases.