What is the NOAEL for 3,7-Dimethyl-2,6-nonadienenitrile?
3,7-Dimethyl-2,6-nonadienenitrile has 13 NOAEL studies in the database. The lowest reported value is 5.48 mg/m3 via inhalation in Human. Source: ToxValDB_GESTIS_DNEL.
NOAEL Data
REACH Registered
Cosmetic Ingredient
3,7-Dimethyl-2,6-nonadienenitrile
Also known as: 2,6-Nonadienenitrile, 3,7-dimethyl-, 3,7-Dimethylnona-2,6-dienenitrile, EC No.: 263-214-5, EINECS 263-214-5, Lemonile (+2 more)
CAS 61792-11-8
3,7-Dimethyl-2,6-nonadienenitrile (CAS 61792-11-8) is a chemical substance. Key regulatory status: REACH registered, 1 regulatory/inventory list, cosmetic ingredient cross-reference; source data from EPA ToxValDB, EPA CPDat, AICIS, ECHA REACH.
SOURCE
noael studies public
NOAEL studies
13
SOURCE
chemical inventory jurisdictions
Regulatory lists
1
SOURCE
eu clp annex vi
GHS signal
Not classified
Chemical Identity
CAS, identifiers, formula, and alternate names for the matched substance record.
SOURCE
DSSTox identifiers
13 fields
Name
3,7-Dimethyl-2,6-nonadienenitrile
CAS Number
61792-11-8
DTXSID
DTXSID1052296
Molecular Formula
C11H17N
InChI Key
DHJVLXVXNFUSMU-UHFFFAOYSA-N
Monoisotopic Mass
163.1361
Synonyms
2,6-Nonadienenitrile, 3,7-dimethyl-3,7-Dimethylnona-2,6-dienenitrileEC No.: 263-214-5EINECS 263-214-5Lemonile263-214-5BRN 11330491
Functional Uses
Industrial and product-use categories associated with this substance.
SOURCE
EPA CPDat
37 records
Fragrance
Regulatory Lists
Inventory, screening, and regulatory list matches from public chemical databases.
SOURCE
EPA CPDat
1 records
| List | Keyword | Source |
|---|---|---|
| IFRA Transparency | IFRA | IFRA |
NOAEL Studies
Toxicology endpoints rendered from public NOAEL study rows.
SOURCE
NOAEL studies
Showing 13 of 13 studies
| Value | Unit | Endpoint | Route | Species | Source |
|---|---|---|---|---|---|
| =5.48 | mg/m3 | DNEL systemic | inhalation | Human | ToxValDB_GESTIS_DNEL |
| B8MK5EZU56 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| B8MK5EZU56 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| B8MK5EZU56 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| B8MK5EZU56 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| - | % | Incidence of positive responses | Dermal | Human | NTP_ICE_skin_sensitization |
| 4050 | ug/cm2 | Induction dose per skin area | Dermal | Human | NTP_ICE_skin_sensitization |
| =2600 | mg/kg bw | LD50 | oral | Rat | NTP_ICE_acute_oral |
| >=111 | mg/kg bw/day | NOAEL | oral | Rat | ToxValDB_ECHA_IUCLID |
| >=128 | mg/kg bw/day | NOAEL | oral | Rat | ToxValDB_ECHA_IUCLID |
| >=1000 | ppm | NOAEL | oral | Rat | ToxValDB_ECHA_IUCLID |
| >=1200 | ppm | NOAEL | oral | Rat | ToxValDB_ECHA_IUCLID |
| 3 | unitless | Relative reliability score | Dermal | Human | NTP_ICE_skin_sensitization |
Showing 13 of 13 studies
REACH Registration
Registration status from the ECHA REACH registered substances database.
SOURCE
ECHA (EU)
1 records
| Status | Name | EC Number | Link |
|---|---|---|---|
| Registered | 3,7-dimethylnona-2,6-dienenitrile | 263-214-5 | ECHA overview → |
Australian Status (AICIS)
Australian industrial chemicals inventory status and applicable conditions.
SOURCE
AICIS inventory
1 records
Inventory Status
listed
Cosmetic Safety Profile
Same-CAS cosmetic ingredient record for cross-vertical context.
SOURCE
CosIng / Ingredients DB
EU Status
permitted
Max
-
Category
Fragrance
Frequently Asked Questions
What regulatory lists include 3,7-Dimethyl-2,6-nonadienenitrile?
3,7-Dimethyl-2,6-nonadienenitrile appears on 1 regulatory/inventory list including IFRA Transparency. Source: EPA CPDat.
Is 3,7-Dimethyl-2,6-nonadienenitrile used in cosmetics?
Yes, 3,7-Dimethyl-2,6-nonadienenitrile is also indexed as a cosmetic ingredient under the name Homogeranyl Nitrile. View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.
Where does the safety data for 3,7-Dimethyl-2,6-nonadienenitrile come from?
Safety data is sourced from EPA ToxValDB, EPA CPDat, AICIS (Australian Industrial Chemicals Introduction Scheme), EPA DSSTox, ECHA REACH, CosIng / Ingredients DB. All data traces to primary regulatory sources and is updated from official government databases.
Is 3,7-Dimethyl-2,6-nonadienenitrile used outside industrial chemicals?
3,7-Dimethyl-2,6-nonadienenitrile also appears in cosmetics databases.