What is the NOAEL for Manganese(2+) dihexonate?
Manganese(2+) dihexonate has 4 NOAEL studies in the database. The lowest reported value is 7G09WJ8QIR UNII. Source: openFDA substances.
NOAEL Data
Cosmetic Ingredient
Manganese(2+) dihexonate
CAS 6485-39-8
Manganese(2+) dihexonate (CAS 6485-39-8) is a chemical substance. Key regulatory status: 5 regulatory/inventory lists, cosmetic ingredient cross-reference; source data from EPA ToxValDB, EPA CPDat, AICIS.
Cross-Vertical Regulatory Divergence
Manganese(2+) dihexonate is classified GHS Danger (H302, H318, H372, H319) in the chemicals database but is allowed in EU cosmetics.
SOURCE
Cross-vertical comparison
Cosmetics: ingredients.eu_status; Chemicals: ghs_classifications.signal_word/hazard_statement_code
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noael studies public
NOAEL studies
4
SOURCE
chemical inventory jurisdictions
Regulatory lists
5
SOURCE
eu clp annex vi
GHS signal
Not classified
Chemical Identity
CAS, identifiers, formula, and alternate names for the matched substance record.
SOURCE
DSSTox identifiers
6 fields
Name
Manganese(2+) dihexonate
CAS Number
6485-39-8
DTXSID
DTXSID30983438
Molecular Formula
2C6H12O7.Mn
InChI Key
OXHQNTSSPHKCPB-IYEMJOQQSA-L
Monoisotopic Mass
447.054649
Functional Uses
Industrial and product-use categories associated with this substance.
SOURCE
EPA CPDat
6 records
Softener and conditionerNo specific technical functionBiocideFlavouring and nutrient
Regulatory Lists
Inventory, screening, and regulatory list matches from public chemical databases.
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EPA CPDat
5 records
| List | Keyword | Source |
|---|---|---|
| active_ingredient; animal_products; Europe; pharmaceutical; residue | EU | CPCat |
| Europe; supplements | EU | CPCat |
| Europe; food_additive; supplements | EU | CPCat |
| food_additive; Substances Added to Food (formerly EAFUS) (2/2019) | FDA | United States Food and Drug Administration (FDA) |
| Canada; pharmaceutical | DrugBank | DrugBank |
NOAEL Studies
Toxicology endpoints rendered from public NOAEL study rows.
SOURCE
NOAEL studies
Showing 4 of 4 studies
| Value | Unit | Endpoint | Route | Species | Source |
|---|---|---|---|---|---|
| 7G09WJ8QIR | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 7G09WJ8QIR | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 7G09WJ8QIR | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 7G09WJ8QIR | UNII | FDA UNII substance identifier | - | - | openFDA substances |
Showing 4 of 4 studies
Australian Status (AICIS)
Australian industrial chemicals inventory status and applicable conditions.
SOURCE
AICIS inventory
1 records
Inventory Status
listed
Cosmetic Safety Profile
Same-CAS cosmetic ingredient record for cross-vertical context.
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CosIng / Ingredients DB
EU Status
permitted
Max
-
Category
Skin Conditioning
Food Safety Data
Same-CAS food additive, ADI, and GRAS records where available.
SOURCE
EFSA / FDA GRAS
1 records
1 food-safety record found.
View full food safety profile →Frequently Asked Questions
What regulatory lists include Manganese(2+) dihexonate?
Manganese(2+) dihexonate appears on 5 regulatory/inventory lists including active_ingredient; animal_products; Europe; pharmaceutical; residue, Europe; supplements, Europe; food_additive; supplements, and 2 more. Source: EPA CPDat.
Is Manganese(2+) dihexonate used in cosmetics?
Yes, Manganese(2+) dihexonate is also indexed as a cosmetic ingredient under the name Manganese Gluconate. View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.
Where does the safety data for Manganese(2+) dihexonate come from?
Safety data is sourced from EPA ToxValDB, EPA CPDat, AICIS (Australian Industrial Chemicals Introduction Scheme), EPA DSSTox, CosIng / Ingredients DB, EFSA / FDA GRAS. All data traces to primary regulatory sources and is updated from official government databases.
Does Manganese(2+) dihexonate have different safety status in cosmetics vs industrial chemicals?
Manganese(2+) dihexonate is classified GHS Danger (H302, H318, H372, H319) in the chemicals database but is allowed in EU cosmetics.
Is Manganese(2+) dihexonate used outside industrial chemicals?
Manganese(2+) dihexonate also appears in cosmetics, food safety databases.