What is the NOAEL for Isosorbide dicaprylate?
Isosorbide dicaprylate has 6 NOAEL studies in the database. The lowest reported value is 141 mg/m3 via inhalation in Human. Source: ToxValDB_GESTIS_DNEL.
NOAEL Data
REACH Registered
Cosmetic Ingredient
Isosorbide dicaprylate
Also known as: UNII-0IK29C4889, D-Glucitol, 1,4:3,6-dianhydro-, dioctanoate, Furo(3,2-b)furan, d-glucitol deriv, Nikkol sorester 208, Synovea DOI
CAS 64896-70-4
Isosorbide dicaprylate (CAS 64896-70-4) is a chemical substance. Key regulatory status: REACH registered, cosmetic ingredient cross-reference; source data from EPA ToxValDB, EPA CPDat, ECHA REACH.
SOURCE
noael studies public
NOAEL studies
6
SOURCE
chemical inventory jurisdictions
Regulatory lists
0
SOURCE
eu clp annex vi
GHS signal
Not classified
Chemical Identity
CAS, identifiers, formula, and alternate names for the matched substance record.
SOURCE
DSSTox identifiers
11 fields
Name
Isosorbide dicaprylate
CAS Number
64896-70-4
DTXSID
DTXSID60215219
Molecular Formula
C22H38O6
InChI Key
BIOGOMUNGWOQHV-GMQQQROESA-N
Monoisotopic Mass
398.266839
Synonyms
UNII-0IK29C4889D-Glucitol, 1,4:3,6-dianhydro-, dioctanoateFuro(3,2-b)furan, d-glucitol derivNikkol sorester 208Synovea DOI
Functional Uses
Industrial and product-use categories associated with this substance.
SOURCE
EPA CPDat
2 records
Softener and conditioner
NOAEL Studies
Toxicology endpoints rendered from public NOAEL study rows.
SOURCE
NOAEL studies
Showing 6 of 6 studies
| Value | Unit | Endpoint | Route | Species | Source |
|---|---|---|---|---|---|
| =141 | mg/m3 | DNEL systemic | inhalation | Human | ToxValDB_GESTIS_DNEL |
| 0IK29C4889 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 0IK29C4889 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 0IK29C4889 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 0IK29C4889 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| >2000 | mg/kg bw | LD50 | oral | Rat | NTP_ICE_acute_oral |
Showing 6 of 6 studies
REACH Registration
Registration status from the ECHA REACH registered substances database.
SOURCE
ECHA (EU)
1 records
| Status | Name | EC Number | Link |
|---|---|---|---|
| Registered | (3R,3aR,6S,6aR)-hexahydrofuro[3,2-b]furan-3,6-diyl dioctanoate | 807-840-4 | ECHA overview → |
Cosmetic Safety Profile
Same-CAS cosmetic ingredient record for cross-vertical context.
SOURCE
CosIng / Ingredients DB
EU Status
permitted
Max
-
Category
Emollient
Frequently Asked Questions
Is Isosorbide dicaprylate used in cosmetics?
Yes, Isosorbide dicaprylate is also indexed as a cosmetic ingredient under the name Isosorbide Dicaprylate. View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.
Where does the safety data for Isosorbide dicaprylate come from?
Safety data is sourced from EPA ToxValDB, EPA CPDat, EPA DSSTox, ECHA REACH, CosIng / Ingredients DB. All data traces to primary regulatory sources and is updated from official government databases.
Is Isosorbide dicaprylate used outside industrial chemicals?
Isosorbide dicaprylate also appears in cosmetics databases.