What is the NOAEL for Pyridoxine?
Pyridoxine has 6 NOAEL studies in the database. The lowest reported value is 0 uL/min/10^6 cells in Human. Source: NTP ICE adme parameters.
NOAEL Data
REACH Registered
Cosmetic Ingredient
Pyridoxine
Also known as: 3,4-Pyridinedimethanol, 5-hydroxy-6-methyl-, EINECS 200-603-0, 2-Methyl-3-hydroxy-4,5-bis(hydroxymethyl)pyridine, 2-Picoline-4,5-dimethanol, 3-hydroxy-, 2-Methyl-3-hydroxy-4,5-dihydroxymethyl-pyridin (+15 more)
CAS 65-23-6
Pyridoxine (CAS 65-23-6) is a chemical substance. Key regulatory status: REACH registered, 6 regulatory/inventory lists, cosmetic ingredient cross-reference; source data from EPA ToxValDB, EPA CPDat, ECHA REACH.
SOURCE
NOAEL studies
NOAEL studies
6
SOURCE
Chemical inventory jurisdictions
Regulatory lists
6
SOURCE
EU CLP Annex VI
GHS signal
Not classified
Chemical Identity
CAS, identifiers, formula, and alternate names for the matched substance record.
SOURCE
DSSTox identifiers
26 fields
Name
Pyridoxine
CAS Number
65-23-6
DTXSID
DTXSID4023541
Molecular Formula
C8H11NO3
InChI Key
LXNHXLLTXMVWPM-UHFFFAOYSA-N
Monoisotopic Mass
169.073893
Synonyms
3,4-Pyridinedimethanol, 5-hydroxy-6-methyl-EINECS 200-603-02-Methyl-3-hydroxy-4,5-bis(hydroxymethyl)pyridine2-Picoline-4,5-dimethanol, 3-hydroxy-2-Methyl-3-hydroxy-4,5-dihydroxymethyl-pyridinUNII-KV2JZ1BI6Z2-methyl-3-hydroxy-4,5-dihydroxymethylpyridine2-methyl-4,5-dimethylol-pyridin-3-ol3-Hydroxy-2-Picoline-4,5-dimethanol3-hydroxy-4,5-dimethylol-alpha-picoline4,5-bis(hydroxymethyl)-2-methyl-pyridin-3-ol5-hydroxy-6-methyl-3,4-pyridinedimethanol
Functional Uses
Industrial and product-use categories associated with this substance.
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EPA CPDat
8 records
Anti-static agentSoftener and conditioner
Regulatory Lists
Inventory, screening, and regulatory list matches from public chemical databases.
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EPA CPDat
6 records
| List | Keyword | Source |
|---|---|---|
| inert_ingredient; non_food_use; Pesticides | EPA | CPCat |
| pharmaceutical | US International Trade Commission | CPCat |
| food_additive; Substances Added to Food (formerly EAFUS) (2/2019) | FDA | United States Food and Drug Administration (FDA) |
| Canada; pharmaceutical | DrugBank | DrugBank |
| Canada; pharmaceutical | DrugBank | DrugBank |
| Canada; pharmaceutical | DrugBank | DrugBank |
NOAEL Studies
Toxicology endpoints rendered from public NOAEL study rows.
SOURCE
NOAEL studies
Showing 6 of 6 studies
| Value | Unit | Endpoint | Route | Species | Source |
|---|---|---|---|---|---|
| - | uL/min/10^6 cells | Clint | - | Human | NTP ICE adme parameters |
| KV2JZ1BI6Z | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| KV2JZ1BI6Z | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| KV2JZ1BI6Z | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| KV2JZ1BI6Z | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| - | unitless | Model Score | - | - | NTP ICE endocrine |
Showing 6 of 6 studies
REACH Registration
Registration status from the ECHA REACH registered substances database.
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ECHA
1 records
| Status | Name | EC Number | Link |
|---|---|---|---|
| Registered | Pyridoxine | 200-603-0 | ECHA overview → |
Cosmetic Safety Profile
Same-CAS cosmetic ingredient record for cross-vertical context.
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CosIng / Ingredients DB
EU Status
permitted
Max
-
Category
active
Pharmaceutical Data
Same-CAS pharmaceutical records from drug and bioactivity sources.
SOURCE
ChEMBL / DailyMed
PYRIDOXINE
ChEMBL Phase
4
Adverse Events
5395
Bioactivity
9
Food Safety Data
Same-CAS food additive, ADI, and GRAS records where available.
SOURCE
EFSA
1 records
1 food-safety record found.
View full food safety profile →Frequently Asked Questions
What regulatory lists include Pyridoxine?
Pyridoxine appears on 4 regulatory/inventory lists including inert_ingredient; non_food_use; Pesticides, pharmaceutical, food_additive; Substances Added to Food (formerly EAFUS) (2/2019), and 1 more. Source: EPA CPDat.
Is Pyridoxine used in cosmetics?
Yes, Pyridoxine is also indexed as a cosmetic ingredient under the name Pyridoxine. View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.
Where does the safety data for Pyridoxine come from?
Safety data is sourced from EPA ToxValDB, EPA CPDat, EPA DSSTox, ECHA REACH, CosIng / Ingredients DB, ChEMBL / DailyMed, EFSA / FDA GRAS. All data traces to primary regulatory sources and is updated from official government databases.
Is Pyridoxine used outside industrial chemicals?
Pyridoxine also appears in cosmetics, pharmaceutical, food safety databases.