What is the NOAEL for L-Methionine, N-acetyl-?
L-Methionine, N-acetyl- has 7 NOAEL studies in the database. The lowest reported value is 9J12WX5B6A UNII. Source: openFDA substances.
NOAEL Data
Cosmetic Ingredient
L-Methionine, N-acetyl-
CAS 65-82-7
L-Methionine, N-acetyl- (CAS 65-82-7) is a chemical substance. Key regulatory status: 4 regulatory/inventory lists, cosmetic ingredient cross-reference; source data from EPA ToxValDB, EPA CPDat.
Cross-Vertical Regulatory Divergence
L-Methionine, N-acetyl- is classified GHS Danger (H315, H318, H319, H335) in the chemicals database but is allowed in EU cosmetics.
SOURCE
Cross-vertical comparison
Cosmetics: ingredients.eu_status; Chemicals: ghs_classifications.signal_word/hazard_statement_code
SOURCE
noael studies public
NOAEL studies
7
SOURCE
chemical inventory jurisdictions
Regulatory lists
4
SOURCE
eu clp annex vi
GHS signal
Not classified
Chemical Identity
CAS, identifiers, formula, and alternate names for the matched substance record.
SOURCE
DSSTox identifiers
6 fields
Name
L-Methionine, N-acetyl-
CAS Number
65-82-7
DTXSID
DTXSID00883214
Molecular Formula
C7H13NO3S
InChI Key
XUYPXLNMDZIRQH-LURJTMIESA-N
Monoisotopic Mass
191.061614
Functional Uses
Industrial and product-use categories associated with this substance.
SOURCE
EPA CPDat
2 records
Softener and conditionerFlavouring and nutrient
Regulatory Lists
Inventory, screening, and regulatory list matches from public chemical databases.
SOURCE
EPA CPDat
4 records
| List | Keyword | Source |
|---|---|---|
| Canada; Personal care; Substances in PCP - Canada (4/2014) | Government of Canada | CPCat |
| active_ingredient; animal_products; Europe; pharmaceutical; residue | EU | CPCat |
| food_additive; Substances Added to Food (formerly EAFUS) (2/2019) | FDA | United States Food and Drug Administration (FDA) |
| Canada; pharmaceutical | DrugBank | DrugBank |
NOAEL Studies
Toxicology endpoints rendered from public NOAEL study rows.
SOURCE
NOAEL studies
Showing 7 of 7 studies
| Value | Unit | Endpoint | Route | Species | Source |
|---|---|---|---|---|---|
| 9J12WX5B6A | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 9J12WX5B6A | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 9J12WX5B6A | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 9J12WX5B6A | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 1200 | mg/kg bw/day | NOAEL | oral | rat | COSMOS_DB |
| 2000 | mg/kg bw/day | NOAEL | oral | rat | COSMOS_DB |
| 3850 | mg/kg bw/day | NOAEL | oral | rat | COSMOS_DB |
Showing 7 of 7 studies
Cosmetic Safety Profile
Same-CAS cosmetic ingredient record for cross-vertical context.
SOURCE
CosIng / Ingredients DB
EU Status
permitted
Max
-
Category
conditioning-agent
Cannabis Data
Same-CAS cannabis compliance and lab records where available.
SOURCE
Cannabis regulatory / lab data
efsa substances
1 cannabis record found in efsa substances.
View full cannabis profile →Frequently Asked Questions
What regulatory lists include L-Methionine, N-acetyl-?
L-Methionine, N-acetyl- appears on 4 regulatory/inventory lists including Canada; Personal care; Substances in PCP - Canada (4/2014), active_ingredient; animal_products; Europe; pharmaceutical; residue, food_additive; Substances Added to Food (formerly EAFUS) (2/2019), and 1 more. Source: EPA CPDat.
Is L-Methionine, N-acetyl- used in cosmetics?
Yes, L-Methionine, N-acetyl- is also indexed as a cosmetic ingredient under the name Acetyl Methionine. View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.
Where does the safety data for L-Methionine, N-acetyl- come from?
Safety data is sourced from EPA ToxValDB, EPA CPDat, EPA DSSTox, CosIng / Ingredients DB, cannabis regulatory/lab databases. All data traces to primary regulatory sources and is updated from official government databases.
Does L-Methionine, N-acetyl- have different safety status in cosmetics vs industrial chemicals?
L-Methionine, N-acetyl- is classified GHS Danger (H315, H318, H319, H335) in the chemicals database but is allowed in EU cosmetics.
Is L-Methionine, N-acetyl- used outside industrial chemicals?
L-Methionine, N-acetyl- also appears in cosmetics, cannabis databases.