NOAEL Data REACH Registered Cosmetic Ingredient

C.I. Pigment Red 112

Also known as: 2-Naphthalenecarboxamide, 3-hydroxy-N-(2-methylphenyl)-4-[2-(2,4,5-trichlorophenyl)diazenyl]-, 3-Hydroxy-N-(o-tolyl)-4-((2,4,5-trichlorophenyl)azo)naphthalene-2-carboxamide, 2-Naphthalenecarboxamide, 3-hydroxy-N-(2-methylphenyl)-4-((2,4,5-trichlorophenyl)azo)-, EINECS 229-440-3, UNII-6S30UYY7FD

CAS 6535-46-2

C.I. Pigment Red 112 (CAS 6535-46-2) is a chemical substance. Key regulatory status: REACH registered, 4 regulatory/inventory lists, cosmetic ingredient cross-reference; source data from EPA ToxValDB, EPA CPDat, AICIS, ECHA REACH.

View cosmetic safety profile for CI 12370 (Pigment Red 112 / Permanent Red FGR) →

SOURCE noael studies public
NOAEL studies
5
SOURCE chemical inventory jurisdictions
Regulatory lists
4
SOURCE eu clp annex vi
GHS signal
Not classified

Chemical Identity

CAS, identifiers, formula, and alternate names for the matched substance record.

SOURCE DSSTox identifiers 11 fields
Name
C.I. Pigment Red 112
CAS Number
6535-46-2
DTXSID
DTXSID1064403
Molecular Formula
C24H16Cl3N3O2
InChI Key
JQNJCQYNSLCFAC-UHFFFAOYSA-N
Monoisotopic Mass
483.03081
Synonyms
2-Naphthalenecarboxamide, 3-hydroxy-N-(2-methylphenyl)-4-[2-(2,4,5-trichlorophenyl)diazenyl]-3-Hydroxy-N-(o-tolyl)-4-((2,4,5-trichlorophenyl)azo)naphthalene-2-carboxamide2-Naphthalenecarboxamide, 3-hydroxy-N-(2-methylphenyl)-4-((2,4,5-trichlorophenyl)azo)-EINECS 229-440-3UNII-6S30UYY7FD

Functional Uses

Industrial and product-use categories associated with this substance.

SOURCE EPA CPDat 10 records
DyePigment

Regulatory Lists

Inventory, screening, and regulatory list matches from public chemical databases.

SOURCE EPA CPDat 4 records
ListKeywordSource
Europe; Personal careEuropean CommissionCosIng
banned; Europe; Personal careEuropean CommissionCosIng
Europe; plastic_additiveEuropean Chemicals AgencyEuropean Chemicals Agency (ECHA)
Europe; Toys and children's productsDanish Environmental Protection AgencyDanish EPA

NOAEL Studies

Toxicology endpoints rendered from public NOAEL study rows.

SOURCE NOAEL studies Showing 5 of 5 studies
ValueUnitEndpointRouteSpeciesSource
=3mg/m3DNEL localinhalationHumanToxValDB_GESTIS_DNEL
6S30UYY7FDUNIIFDA UNII substance identifier--openFDA substances
6S30UYY7FDUNIIFDA UNII substance identifier--openFDA substances
6S30UYY7FDUNIIFDA UNII substance identifier--openFDA substances
6S30UYY7FDUNIIFDA UNII substance identifier--openFDA substances

Showing 5 of 5 studies

REACH Registration

Registration status from the ECHA REACH registered substances database.

SOURCE ECHA (EU) 1 records
StatusNameEC NumberLink
Registered3-hydroxy-N-(o-tolyl)-4-[(2,4,5-trichlorophenyl)azo]naphthalene-2-carboxamide229-440-3ECHA overview →

Australian Status (AICIS)

Australian industrial chemicals inventory status and applicable conditions.

SOURCE AICIS inventory 1 records
Inventory Status
listed

Cosmetic Safety Profile

Same-CAS cosmetic ingredient record for cross-vertical context.

SOURCE CosIng / Ingredients DB
EU Status
restricted
Max
-
Category
Colorants
View full cosmetic safety profile →

Frequently Asked Questions

What is the NOAEL for C.I. Pigment Red 112?

C.I. Pigment Red 112 has 5 NOAEL studies in the database. The lowest reported value is 3 mg/m3 via inhalation in Human. Source: ToxValDB_GESTIS_DNEL.

What regulatory lists include C.I. Pigment Red 112?

C.I. Pigment Red 112 appears on 4 regulatory/inventory lists including Europe; Personal care, banned; Europe; Personal care, Europe; plastic_additive, and 1 more. Source: EPA CPDat.

Is C.I. Pigment Red 112 used in cosmetics?

Yes, C.I. Pigment Red 112 is also indexed as a cosmetic ingredient under the name CI 12370 (Pigment Red 112 / Permanent Red FGR). View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.

Where does the safety data for C.I. Pigment Red 112 come from?

Safety data is sourced from EPA ToxValDB, EPA CPDat, AICIS (Australian Industrial Chemicals Introduction Scheme), EPA DSSTox, ECHA REACH, CosIng / Ingredients DB. All data traces to primary regulatory sources and is updated from official government databases.

Is C.I. Pigment Red 112 used outside industrial chemicals?

C.I. Pigment Red 112 also appears in cosmetics databases.