What is the NOAEL for 2H-Pyran-2-one, 4,6-dimethyl-?
2H-Pyran-2-one, 4,6-dimethyl- has 4 NOAEL studies in the database. The lowest reported value is G2MA4KIQ1B UNII. Source: openFDA substances.
NOAEL Data
Cosmetic Ingredient
2H-Pyran-2-one, 4,6-dimethyl-
Also known as: 5-17-09-00409, BRN 0002468, 4,6-Dimethylcoumalin, 2,4-Dimethyl-alpha-pyrone, 4,6-Dimethyl-alpha-pyrone (+4 more)
CAS 675-09-2
2H-Pyran-2-one, 4,6-dimethyl- (CAS 675-09-2) is a chemical substance. Key regulatory status: 1 regulatory/inventory list, cosmetic ingredient cross-reference; source data from EPA ToxValDB, EPA CPDat, AICIS.
SOURCE
noael studies public
NOAEL studies
4
SOURCE
chemical inventory jurisdictions
Regulatory lists
1
SOURCE
eu clp annex vi
GHS signal
Not classified
Chemical Identity
CAS, identifiers, formula, and alternate names for the matched substance record.
SOURCE
DSSTox identifiers
15 fields
Name
2H-Pyran-2-one, 4,6-dimethyl-
CAS Number
675-09-2
DTXSID
DTXSID6060973
Molecular Formula
C7H8O2
InChI Key
IXYLIUKQQQXXON-UHFFFAOYSA-N
Monoisotopic Mass
124.052429
Synonyms
5-17-09-00409BRN 00024684,6-Dimethylcoumalin2,4-Dimethyl-alpha-pyrone4,6-Dimethyl-alpha-pyrone4,6-Dimethyl-2-pyroneEINECS 211-618-7Mesitene lactoneNSC 402790
Functional Uses
Industrial and product-use categories associated with this substance.
SOURCE
EPA CPDat
2 records
Fragrance
Regulatory Lists
Inventory, screening, and regulatory list matches from public chemical databases.
SOURCE
EPA CPDat
1 records
| List | Keyword | Source |
|---|---|---|
| IFRA Transparency | IFRA | IFRA |
NOAEL Studies
Toxicology endpoints rendered from public NOAEL study rows.
SOURCE
NOAEL studies
Showing 4 of 4 studies
| Value | Unit | Endpoint | Route | Species | Source |
|---|---|---|---|---|---|
| G2MA4KIQ1B | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| G2MA4KIQ1B | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| G2MA4KIQ1B | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| G2MA4KIQ1B | UNII | FDA UNII substance identifier | - | - | openFDA substances |
Showing 4 of 4 studies
Australian Status (AICIS)
Australian industrial chemicals inventory status and applicable conditions.
SOURCE
AICIS inventory
1 records
Inventory Status
listed
Cosmetic Safety Profile
Same-CAS cosmetic ingredient record for cross-vertical context.
SOURCE
CosIng / Ingredients DB
EU Status
permitted
Max
-
Category
Fragrance
Pharmaceutical Data
Same-CAS pharmaceutical records from drug and bioactivity sources.
SOURCE
EMBL-EBI ChEMBL
CHEMBL372284
ChEMBL Phase
Not listed
Adverse Events
0
Bioactivity
1
Frequently Asked Questions
What regulatory lists include 2H-Pyran-2-one, 4,6-dimethyl-?
2H-Pyran-2-one, 4,6-dimethyl- appears on 1 regulatory/inventory list including IFRA Transparency. Source: EPA CPDat.
Is 2H-Pyran-2-one, 4,6-dimethyl- used in cosmetics?
Yes, 2H-Pyran-2-one, 4,6-dimethyl- is also indexed as a cosmetic ingredient under the name 4,6-Dimethyl-Pyran-2-One. View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.
Where does the safety data for 2H-Pyran-2-one, 4,6-dimethyl- come from?
Safety data is sourced from EPA ToxValDB, EPA CPDat, AICIS (Australian Industrial Chemicals Introduction Scheme), EPA DSSTox, CosIng / Ingredients DB, ChEMBL / DailyMed. All data traces to primary regulatory sources and is updated from official government databases.
Is 2H-Pyran-2-one, 4,6-dimethyl- used outside industrial chemicals?
2H-Pyran-2-one, 4,6-dimethyl- also appears in cosmetics, pharmaceutical databases.