What is the NOAEL for 5-Ethyl-3-hydroxy-4-methylfuran-2(5H)-one?
5-Ethyl-3-hydroxy-4-methylfuran-2(5H)-one has 5 NOAEL studies in the database. The lowest reported value is J007136N0N UNII. Source: openFDA substances.
NOAEL Data
Cosmetic Ingredient
5-Ethyl-3-hydroxy-4-methylfuran-2(5H)-one
Also known as: 3-Hydroxy-4-methyl-5-ethyl-2-furanone, 2(5H)-Furanone, 5-ethyl-3-hydroxy-4-methyl-, 5-Ethyl-3-hydroxy-4-methyl-2(5H)-furanone, 2,4-Dihydroxy-3-methyl-2-hexenoic acid gamma-lactone, EINECS 211-811-6 (+6 more)
CAS 698-10-2
5-Ethyl-3-hydroxy-4-methylfuran-2(5H)-one (CAS 698-10-2) is a chemical substance. Key regulatory status: 4 regulatory/inventory lists, cosmetic ingredient cross-reference; source data from EPA ToxValDB, EPA CPDat, AICIS.
View cosmetic safety profile for 5-Ethyl-3-Hydroxy-4-Methylfuran-2(5H)-One →
SOURCE
noael studies public
NOAEL studies
5
SOURCE
chemical inventory jurisdictions
Regulatory lists
4
SOURCE
eu clp annex vi
GHS signal
Not classified
Chemical Identity
CAS, identifiers, formula, and alternate names for the matched substance record.
SOURCE
DSSTox identifiers
17 fields
Name
5-Ethyl-3-hydroxy-4-methylfuran-2(5H)-one
CAS Number
698-10-2
DTXSID
DTXSID2052441
Molecular Formula
C7H10O3
InChI Key
IUFQZPBIRYFPFD-UHFFFAOYSA-N
Monoisotopic Mass
142.062994
Synonyms
3-Hydroxy-4-methyl-5-ethyl-2-furanone2(5H)-Furanone, 5-ethyl-3-hydroxy-4-methyl-5-Ethyl-3-hydroxy-4-methyl-2(5H)-furanone2,4-Dihydroxy-3-methyl-2-hexenoic acid gamma-lactoneEINECS 211-811-62-Ethyl-3-methyl-4-hydroxydihydro-(2,5)-furan-5-oneFEMA No. 31532-Hexenoic acid, 2,4-dihydroxy-3-methyl-, gamma-lactone2-Hydroxy-3-methyl-gamma-2-hexenolactone4-Methyl-5-ethyl-3-hydroxyfuranoneUNII-J007136N0N
Functional Uses
Industrial and product-use categories associated with this substance.
SOURCE
EPA CPDat
8 records
FragranceFlavouring and nutrient
Regulatory Lists
Inventory, screening, and regulatory list matches from public chemical databases.
SOURCE
EPA CPDat
4 records
| List | Keyword | Source |
|---|---|---|
| IFRA Transparency | IFRA | IFRA |
| food_additive; Substances Added to Food (formerly EAFUS) (2/2019) | FDA | United States Food and Drug Administration (FDA) |
| consumer_product | P&G | Proctor & Gamble |
| Europe | European Commission | Fl@vis |
NOAEL Studies
Toxicology endpoints rendered from public NOAEL study rows.
SOURCE
NOAEL studies
Showing 5 of 5 studies
| Value | Unit | Endpoint | Route | Species | Source |
|---|---|---|---|---|---|
| J007136N0N | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| J007136N0N | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| J007136N0N | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| J007136N0N | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 1.3 | mg/kg bw/day | NOAEL | oral | rat | COSMOS_DB |
Showing 5 of 5 studies
Australian Status (AICIS)
Australian industrial chemicals inventory status and applicable conditions.
SOURCE
AICIS inventory
1 records
Inventory Status
listed
Cosmetic Safety Profile
Same-CAS cosmetic ingredient record for cross-vertical context.
SOURCE
CosIng / Ingredients DB
EU Status
permitted
Max
-
Category
Fragrance
Cannabis Data
Same-CAS cannabis compliance and lab records where available.
SOURCE
Cannabis regulatory / lab data
efsa substances
1 cannabis record found in efsa substances.
View full cannabis profile →Frequently Asked Questions
What regulatory lists include 5-Ethyl-3-hydroxy-4-methylfuran-2(5H)-one?
5-Ethyl-3-hydroxy-4-methylfuran-2(5H)-one appears on 4 regulatory/inventory lists including IFRA Transparency, food_additive; Substances Added to Food (formerly EAFUS) (2/2019), consumer_product, and 1 more. Source: EPA CPDat.
Is 5-Ethyl-3-hydroxy-4-methylfuran-2(5H)-one used in cosmetics?
Yes, 5-Ethyl-3-hydroxy-4-methylfuran-2(5H)-one is also indexed as a cosmetic ingredient under the name 5-Ethyl-3-Hydroxy-4-Methylfuran-2(5H)-One. View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.
Where does the safety data for 5-Ethyl-3-hydroxy-4-methylfuran-2(5H)-one come from?
Safety data is sourced from EPA ToxValDB, EPA CPDat, AICIS (Australian Industrial Chemicals Introduction Scheme), EPA DSSTox, CosIng / Ingredients DB, cannabis regulatory/lab databases. All data traces to primary regulatory sources and is updated from official government databases.
Is 5-Ethyl-3-hydroxy-4-methylfuran-2(5H)-one used outside industrial chemicals?
5-Ethyl-3-hydroxy-4-methylfuran-2(5H)-one also appears in cosmetics, cannabis databases.