What is the NOAEL for 2-Octynoic acid, 2-propen-1-yl ester?
2-Octynoic acid, 2-propen-1-yl ester has 13 NOAEL studies in the database. The lowest reported value is 0 % via Dermal in Human. Source: NTP_ICE_skin_sensitization.
NOAEL Data
Cosmetic Ingredient
2-Octynoic acid, 2-propen-1-yl ester
CAS 73157-43-4
2-Octynoic acid, 2-propen-1-yl ester (CAS 73157-43-4) is a chemical substance. Key regulatory status: 2 regulatory/inventory lists, cosmetic ingredient cross-reference; source data from EPA ToxValDB, EPA CPDat, AICIS.
Cross-Vertical Regulatory Divergence
2-Octynoic acid, 2-propen-1-yl ester is classified GHS Danger (H302, H311, H312, H315, H317) in the chemicals database but is restricted in EU cosmetics.
SOURCE
Cross-vertical comparison
Cosmetics: ingredients.eu_status; Chemicals: ghs_classifications.signal_word/hazard_statement_code
SOURCE
noael studies public
NOAEL studies
13
SOURCE
chemical inventory jurisdictions
Regulatory lists
2
SOURCE
eu clp annex vi
GHS signal
Not classified
Chemical Identity
CAS, identifiers, formula, and alternate names for the matched substance record.
SOURCE
DSSTox identifiers
6 fields
Name
2-Octynoic acid, 2-propen-1-yl ester
CAS Number
73157-43-4
DTXSID
DTXSID30868231
Molecular Formula
C11H16O2
InChI Key
YJHAHRNANWIZTN-UHFFFAOYSA-N
Monoisotopic Mass
180.11503
Functional Uses
Industrial and product-use categories associated with this substance.
SOURCE
EPA CPDat
2 records
Fragrance
Regulatory Lists
Inventory, screening, and regulatory list matches from public chemical databases.
SOURCE
EPA CPDat
2 records
| List | Keyword | Source |
|---|---|---|
| consumer_product | P&G | Proctor & Gamble |
| Europe; Personal care; restricted | European Commission | CosIng |
NOAEL Studies
Toxicology endpoints rendered from public NOAEL study rows.
SOURCE
NOAEL studies
Showing 13 of 13 studies
| Value | Unit | Endpoint | Route | Species | Source |
|---|---|---|---|---|---|
| 0.5625 | % | Concentration, 5% incidence of positive responses | Dermal | Human | NTP_ICE_skin_sensitization |
| 1.025 | % | Concentration, 5% incidence of positive responses | Dermal | Human | NTP_ICE_skin_sensitization |
| 0.5 | % | Concentration, one positive response | Dermal | Human | NTP_ICE_skin_sensitization |
| 1.25 | % | Concentration, one positive response | Dermal | Human | NTP_ICE_skin_sensitization |
| - | % | Incidence of positive responses | Dermal | Human | NTP_ICE_skin_sensitization |
| 2.439 | % | Incidence of positive responses | Dermal | Human | NTP_ICE_skin_sensitization |
| 11.11 | % | Incidence of positive responses | Dermal | Human | NTP_ICE_skin_sensitization |
| 77.5 | ug/cm2 | Induction dose per skin area | Dermal | Human | NTP_ICE_skin_sensitization |
| 310 | ug/cm2 | Induction dose per skin area | Dermal | Human | NTP_ICE_skin_sensitization |
| 775 | ug/cm2 | Induction dose per skin area | Dermal | Human | NTP_ICE_skin_sensitization |
| 348.8 | ug/cm2 | Induction dose per skin area, 5% incidence of positive responses | Dermal | Human | NTP_ICE_skin_sensitization |
| 635.5 | ug/cm2 | Induction dose per skin area, 5% incidence of positive responses | Dermal | Human | NTP_ICE_skin_sensitization |
| 3 | unitless | Relative reliability score | Dermal | Human | NTP_ICE_skin_sensitization |
Showing 13 of 13 studies
Australian Status (AICIS)
Australian industrial chemicals inventory status and applicable conditions.
SOURCE
AICIS inventory
1 records
Inventory Status
listed
Cosmetic Safety Profile
Same-CAS cosmetic ingredient record for cross-vertical context.
SOURCE
CosIng / Ingredients DB
EU Status
restricted
Max
-
Category
Fragrance
Frequently Asked Questions
What regulatory lists include 2-Octynoic acid, 2-propen-1-yl ester?
2-Octynoic acid, 2-propen-1-yl ester appears on 2 regulatory/inventory lists including consumer_product, Europe; Personal care; restricted. Source: EPA CPDat.
Is 2-Octynoic acid, 2-propen-1-yl ester used in cosmetics?
Yes, 2-Octynoic acid, 2-propen-1-yl ester is also indexed as a cosmetic ingredient under the name Allyl Heptine Carbonate. View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.
Where does the safety data for 2-Octynoic acid, 2-propen-1-yl ester come from?
Safety data is sourced from EPA ToxValDB, EPA CPDat, AICIS (Australian Industrial Chemicals Introduction Scheme), EPA DSSTox, CosIng / Ingredients DB. All data traces to primary regulatory sources and is updated from official government databases.
Does 2-Octynoic acid, 2-propen-1-yl ester have different safety status in cosmetics vs industrial chemicals?
2-Octynoic acid, 2-propen-1-yl ester is classified GHS Danger (H302, H311, H312, H315, H317) in the chemicals database but is restricted in EU cosmetics.
Is 2-Octynoic acid, 2-propen-1-yl ester used outside industrial chemicals?
2-Octynoic acid, 2-propen-1-yl ester also appears in cosmetics databases.