Warning GHS08 NOAEL Data Cosmetic Ingredient

2-Ethylhexyl 2-ethylhexanoate

Also known as: 2-Ethylhexanoic acid, 2-ethylhexyl ester, 2-Ethylhexylester kyseliny 2-ethylkapronove, Hexanoic acid, 2-ethyl-, 2-ethylhexyl ester, BRN 1777190, EINECS 231-057-1 (+1 more)

CAS 7425-14-1

2-Ethylhexyl 2-ethylhexanoate (CAS 7425-14-1) is a chemical substance with GHS signal word Warning; key hazard signal: H361d ***. Key regulatory status: 2 regulatory/inventory lists, cosmetic ingredient cross-reference; source data from ECHA CLP, EPA ToxValDB, EPA CPDat, AICIS.

View cosmetic safety profile for Ethylhexyl Ethylhexanoate ⚠️ →

SOURCE noael studies public
NOAEL studies
5
SOURCE chemical inventory jurisdictions
Regulatory lists
2
SOURCE eu clp annex vi
GHS signal
Warning

Chemical Identity

CAS, identifiers, formula, and alternate names for the matched substance record.

SOURCE DSSTox identifiers 12 fields
Name
2-Ethylhexyl 2-ethylhexanoate
CAS Number
7425-14-1
DTXSID
DTXSID9052478
Molecular Formula
C16H32O2
InChI Key
OUCGJMIVSYHBEC-UHFFFAOYSA-N
Monoisotopic Mass
256.24023
Synonyms
2-Ethylhexanoic acid, 2-ethylhexyl ester2-Ethylhexylester kyseliny 2-ethylkapronoveHexanoic acid, 2-ethyl-, 2-ethylhexyl esterBRN 1777190EINECS 231-057-1UNII-430RJA6715

GHS / CLP Classification

EU harmonized hazard classification, hazard statements, pictograms, and signal word.

SOURCE EU CLP Annex VI (ECHA) 1 classifications
Hazard ClassH-StatementsPictogramsSignal
Repr. 2H361d ***GHS08Warning

Functional Uses

Industrial and product-use categories associated with this substance.

SOURCE EPA CPDat 5 records
Softener and conditionerFragranceLubricating agent

Regulatory Lists

Inventory, screening, and regulatory list matches from public chemical databases.

SOURCE EPA CPDat 2 records
ListKeywordSource
air; detected; emissions; Europe; Other direct contact consumer goodsDanish Environmental Protection AgencyDanish EPA
banned; Europe; Personal careEuropean CommissionCosIng

NOAEL Studies

Toxicology endpoints rendered from public NOAEL study rows.

SOURCE NOAEL studies Showing 5 of 5 studies
ValueUnitEndpointRouteSpeciesSource
430RJA6715UNIIFDA UNII substance identifier--openFDA substances
430RJA6715UNIIFDA UNII substance identifier--openFDA substances
430RJA6715UNIIFDA UNII substance identifier--openFDA substances
430RJA6715UNIIFDA UNII substance identifier--openFDA substances
=27000mg/kg bwLD50oralRatNTP_ICE_acute_oral

Showing 5 of 5 studies

Australian Status (AICIS)

Australian industrial chemicals inventory status and applicable conditions.

SOURCE AICIS inventory 1 records
Inventory Status
listed

Cosmetic Safety Profile

Same-CAS cosmetic ingredient record for cross-vertical context.

SOURCE CosIng / Ingredients DB
EU Status
prohibited
Max
-
Category
Fragrance
View full cosmetic safety profile →

Frequently Asked Questions

What is the GHS hazard classification for 2-Ethylhexyl 2-ethylhexanoate?

2-Ethylhexyl 2-ethylhexanoate (CAS 7425-14-1) is classified under EU CLP Annex VI as Repr. 2 with signal word Warning. Hazard statements: H361d ***. Source: EU CLP Annex VI (ECHA).

What is the NOAEL for 2-Ethylhexyl 2-ethylhexanoate?

2-Ethylhexyl 2-ethylhexanoate has 5 NOAEL studies in the database. The lowest reported value is 430RJA6715 UNII. Source: openFDA substances.

What regulatory lists include 2-Ethylhexyl 2-ethylhexanoate?

2-Ethylhexyl 2-ethylhexanoate appears on 2 regulatory/inventory lists including air; detected; emissions; Europe; Other direct contact consumer goods, banned; Europe; Personal care. Source: EPA CPDat.

Is 2-Ethylhexyl 2-ethylhexanoate used in cosmetics?

Yes, 2-Ethylhexyl 2-ethylhexanoate is also indexed as a cosmetic ingredient under the name Ethylhexyl Ethylhexanoate ⚠️. View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.

Where does the safety data for 2-Ethylhexyl 2-ethylhexanoate come from?

Safety data is sourced from ECHA CLP Annex VI, EPA ToxValDB, EPA CPDat, AICIS (Australian Industrial Chemicals Introduction Scheme), EPA DSSTox, CosIng / Ingredients DB. All data traces to primary regulatory sources and is updated from official government databases.

Does 2-Ethylhexyl 2-ethylhexanoate have different safety status in cosmetics vs industrial chemicals?

2-Ethylhexyl 2-ethylhexanoate is prohibited in EU cosmetics but has active industrial GHS classifications (H361d).

Is 2-Ethylhexyl 2-ethylhexanoate used outside industrial chemicals?

2-Ethylhexyl 2-ethylhexanoate also appears in cosmetics databases.