What is the NOAEL for 3-Methyl-1,2-cyclopentanedione?
3-Methyl-1,2-cyclopentanedione has 7 NOAEL studies in the database. The lowest reported value is 627E92X64B UNII. Source: openFDA substances.
NOAEL Data
Cosmetic Ingredient
3-Methyl-1,2-cyclopentanedione
Also known as: 1,2-Cyclopentanedione, 3-methyl-, EINECS 212-154-8, FEMA No. 2700, Methylcyclopentenolone
CAS 765-70-8
3-Methyl-1,2-cyclopentanedione (CAS 765-70-8) is a chemical substance. Key regulatory status: 5 regulatory/inventory lists, cosmetic ingredient cross-reference; source data from EPA ToxValDB, EPA CPDat, AICIS.
View cosmetic safety profile for Methylcyclopentenolone (Maple Lactone / MCP) →
SOURCE
noael studies public
NOAEL studies
7
SOURCE
chemical inventory jurisdictions
Regulatory lists
5
SOURCE
eu clp annex vi
GHS signal
Not classified
Chemical Identity
CAS, identifiers, formula, and alternate names for the matched substance record.
SOURCE
DSSTox identifiers
10 fields
Name
3-Methyl-1,2-cyclopentanedione
CAS Number
765-70-8
DTXSID
DTXSID3047716
Molecular Formula
C6H8O2
InChI Key
OACYKCIZDVVNJL-UHFFFAOYSA-N
Monoisotopic Mass
112.052429
Synonyms
1,2-Cyclopentanedione, 3-methyl-EINECS 212-154-8FEMA No. 2700Methylcyclopentenolone
Functional Uses
Industrial and product-use categories associated with this substance.
SOURCE
EPA CPDat
4 records
No specific technical functionFragranceFlavouring and nutrient
Regulatory Lists
Inventory, screening, and regulatory list matches from public chemical databases.
SOURCE
EPA CPDat
5 records
| List | Keyword | Source |
|---|---|---|
| Cleaning products and household care - air freshener; Europe | Danish Environmental Protection Agency | Danish EPA |
| IFRA Transparency | IFRA | IFRA |
| Australia; Food and drug - smoking-related products | New Zealand ESR | CPCat |
| food_additive; Substances Added to Food (formerly EAFUS) (2/2019) | FDA | United States Food and Drug Administration (FDA) |
| consumer_product | P&G | Proctor & Gamble |
NOAEL Studies
Toxicology endpoints rendered from public NOAEL study rows.
SOURCE
NOAEL studies
Showing 7 of 7 studies
| Value | Unit | Endpoint | Route | Species | Source |
|---|---|---|---|---|---|
| 627E92X64B | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 627E92X64B | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 627E92X64B | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 627E92X64B | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| - | % | Incidence of positive responses | Dermal | Human | NTP_ICE_skin_sensitization |
| 2025 | ug/cm2 | Induction dose per skin area | Dermal | Human | NTP_ICE_skin_sensitization |
| 3 | unitless | Relative reliability score | Dermal | Human | NTP_ICE_skin_sensitization |
Showing 7 of 7 studies
Australian Status (AICIS)
Australian industrial chemicals inventory status and applicable conditions.
SOURCE
AICIS inventory
1 records
Inventory Status
listed
Cosmetic Safety Profile
Same-CAS cosmetic ingredient record for cross-vertical context.
SOURCE
CosIng / Ingredients DB
EU Status
permitted
Max
-
Category
Fragrance
Frequently Asked Questions
What regulatory lists include 3-Methyl-1,2-cyclopentanedione?
3-Methyl-1,2-cyclopentanedione appears on 5 regulatory/inventory lists including Cleaning products and household care - air freshener; Europe, IFRA Transparency, Australia; Food and drug - smoking-related products, and 2 more. Source: EPA CPDat.
Is 3-Methyl-1,2-cyclopentanedione used in cosmetics?
Yes, 3-Methyl-1,2-cyclopentanedione is also indexed as a cosmetic ingredient under the name Methylcyclopentenolone (Maple Lactone / MCP). View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.
Where does the safety data for 3-Methyl-1,2-cyclopentanedione come from?
Safety data is sourced from EPA ToxValDB, EPA CPDat, AICIS (Australian Industrial Chemicals Introduction Scheme), EPA DSSTox, CosIng / Ingredients DB. All data traces to primary regulatory sources and is updated from official government databases.
Is 3-Methyl-1,2-cyclopentanedione used outside industrial chemicals?
3-Methyl-1,2-cyclopentanedione also appears in cosmetics databases.